- Mechanical Circulatory Support Devices
- Cardiovascular Function and Risk Factors
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Diabetes Treatment and Management
- Cardiac Imaging and Diagnostics
- Soil Geostatistics and Mapping
- Soil erosion and sediment transport
- Acute Myocardial Infarction Research
- Heart Failure Treatment and Management
- Organic and Molecular Conductors Research
- Remote Sensing in Agriculture
- Molecular Junctions and Nanostructures
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Pancreatic function and diabetes
- Geology and Paleoclimatology Research
- Cardiac Ischemia and Reperfusion
- Livestock Farming and Management
- Particle Detector Development and Performance
- Organic Light-Emitting Diodes Research
- Soil and Water Nutrient Dynamics
- 3D Modeling in Geospatial Applications
- Regional Development and Innovation
- Contact Dermatitis and Allergies
Odense University Hospital
2014-2024
University of Southern Denmark
2020-2024
Kongsberg Innovasjon (Norway)
2020
Metro Health Hospital
2018
Roskilde University
1990-2015
Center for Interdisciplinary Studies of Molecular Interactions
1993-1996
University of Copenhagen
1977-1996
Skin and Cancer Foundation
1990
Geographical Institute
1977-1984
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) improve outcomes in patients with heart failure and a reduced ejection fraction (HFrEF). The association cardiac remodeling has not been investigated.To investigate the outcome of SGLT2i empagliflozin, compared placebo, on HFrEF.This exploratory post hoc analysis included participants stable HFrEF fractions 40% or less, who were randomly enrolled an investigator-initiated, multicenter, double-blind, placebo-controlled randomized clinical...
Data from recent cardiovascular outcome trials in patients with type 2 diabetes (T2D) suggest that sodium-glucose cotransporter (SGLT2) inhibitors can prevent development of heart failure (HF) and prolong life without HF. Ongoing event-driven are investigating whether the same effect is present well-defined The mechanism behind SGLT2 T2D potential overt HF presently unknown. This a randomized, double-blinded, placebo-controlled, parallel group, clinical trial including reduced left...
Abstract Background Concomitant vasoactive drugs are often required to maintain adequate perfusion pressure in patients with acute myocardial infarction (AMI) and cardiogenic shock (CS) receiving hemodynamic support an axial flow pump (Impella CP). Objective To compare the effect of equipotent dosages epinephrine, dopamine, norepinephrine, phenylephrine on cardiac work end-organ a porcine model profound ischemic CS supported Impella CP. Methods was induced 10 pigs by stepwise intracoronary...
Stressed blood volume (SBV) is a major determinant of systemic and pulmonary venous pressures which, in turn, determine left right ventricular fillings regulates cardiac output via the Frank-Starling mechanism. It not known whether inhibition SGLT2 (sodium-glucose cotransporter-2) favorably affects SBV. We investigated effect empagliflozin on estimated SBV patients with heart failure reduced ejection fraction compared placebo.This was post hoc analysis an investigator-initiated,...
This article addresses organisational governance, including perceived reputational concerns, by health data custodians as the principal barrier to timely and transparent research. Although existing literature primarily ethics reviews site-specific research approvals, our experience with a Local Hospital Network uncovered additional active barriers within this complex system. We position these experiences in relation that has documented inefficiencies governance processes lead lost knowledge...
Background/aims Associations between retinal vein occlusion (RVO) and subsequent cardiovascular disease (CVD) or mortality have not been evaluated in a recent cohort, after novel therapeutic options increased referrals for treatment of the condition. We aimed to evaluate overall subtype-stratified risk CVD all-cause following RVO assess any alterations introduction angiostatic therapy Denmark 2011. Methods This nationwide, registry-based cohort study from 1998 2018 4 194 781 individuals....
OBJECTIVESThe clinical classification of myocardial infarction (MI) into five types was introduced in 2007 as a component the universal definition. A Type 5 MI defined related to coronary artery bypass surgery. In setting patients undergoing elective grafting, we set out (i) describe pattern multiple serial cardiac troponin I (cTnI) measurements within 72 h postoperatively and (ii) determine optimal cut-off value ruling or MI.
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) with profound left ventricular (LV) failure is associated inadequate LV emptying. To unload the LV, VA-ECMO can be combined Impella CP (ECMELLA). We hypothesized that ECMELLA improves cardiac energetics compared in a porcine model of cardiogenic shock (CS).
Abstract. Woody vegetation was studied in 44 sites Senegal. Species composition and density were analysed with TWINSPAN Canonical Correspondence Analysis; 16 types defined. A supervised, multispectral multitemporal classification of day night, dry season NOAA‐AVHRR imagery used to identify their distribution a accuracy ranging from 60–100%.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and electrochemical properties of 1,4-dithiafulvenyl-substituted bianthrone molecules with potential application as molecular switchesMikkel Joergensen, Knud Lerstrup, Peter Frederiksen, Thomas Bjoernholm, Sommer-Larsen, Kjeld Schaumburg, Kay Brunfeldt, Klaus BechgaardCite this: J. Org. Chem. 1993, 58, 10, 2785–2790Publication Date (Print):May 1, 1993Publication History Published online1 May 2002Published inissue 1...
Abstract Background and aim This study aimed to assess right ventricular (RV) function during cardiogenic shock due acute left (LV) failure, including LV unloading with Impella CP an added moderate dose of norepinephrine. Methods Cardiogenic was induced by injecting microspheres in the main coronary artery 18 adult Danish Landrace pigs. Conductance catheters were placed both ventricles pressure-volume loops recorded simultaneously. Results failure also impaired RV performance, which...
Madsen, H. B., Nielsen, E. S., ødum, S. (eds.): The Danish Scientific Expedition to Patagonia and Tierra del Fuego 1978–1979. Geografisk Tidsskrift 80: 1–28, June 1980. paper surveys geographical, botanical zoological projects dealt with during six months of travelling fieldwork in the Argentinean Chilean Andes adjacent lowlands: Soil development relation climate. General entomological studies collecting work. Entomological especially within certain families Lepidoptera. Studies on snowbed...
Background Haemodynamic exercise testing is important for evaluating patients with dyspnoea on exertion and preserved ejection fraction. Despite very different pathologies, pressure (aortic stenosis (AS)) volume (mitral regurgitation (MR)) overload diastolic dysfunction after recent acute myocardial infarction (AMI) reach similar filling levels exercise. The pressure–flow relationships (the association between change in cardiac output (∆CO) pulmonary arterial wedge (∆PAWP) may provide...
Blue and red light-emitting diodes were constructed as devices in which a polystyrene/dye blend was sandwiched between calcium electrode transparent indium-tin oxide electrode. As dye molecules, four alkoxy-substituted derivatives of 2,5-dialkoxy-1,4-bis(2-phenylvinyl)benzene (i.e. p-phenylene vinylene oligomers), derivative bisanthracene (2,2′,3,3′-tetrachloro-9,9′-dimethoxy-10,10′-bianthracene) the laser 4-dicyanomethylene-2-methyl-6-(p-dimethylaminophenylvinyl)-4H-pyran (DCM) used. The...
Spatial deterministic simulation models such as DaisyGIS are increasingly being used for decision‐making in European planning. In Denmark specifically, there is an increasing interest at the regional level to use administrative tool. There are, however, uncertainties associated with of these models, partly due spatial variation input parametres. This study evaluates nitrate leaching assessments based on experiments carried out Marbjerg experimental site Roskilde University. The includes...
(1996). A FACILE LARGE SCALE PREPARATION OF RACEMIC 2.2′-DIHYDROXY-1,1′-BINAPHTHYL. Organic Preparations and Procedures International: Vol. 28, No. 4, pp. 484-486.
This article attempts to solve current problems of conceptual fragmentation within the field evolutionary economics. One is that suffers from an assemblage fragmented and scattered concepts (Boschma Martin 2010). We propose a solution this problem in form model exponential expansion. The outlines overall structure function economy as pictographic describes four axiomatic — interactive, directional, emerging, expanding their nature. Taken whole, it provides rudimentary aspects economic system...