A5087465273- Diabetes Treatment and Management
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Diabetes Management and Research
- Heart Failure Treatment and Management
- Bone health and treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes and associated disorders
- Metabolism, Diabetes, and Cancer
- Immunodeficiency and Autoimmune Disorders
- Pancreatic function and diabetes
- Lipoproteins and Cardiovascular Health
- Blood Pressure and Hypertension Studies
- Sarcoidosis and Beryllium Toxicity Research
- Nutrition and Health in Aging
- Bariatric Surgery and Outcomes
- Nutritional Studies and Diet
- Sepsis Diagnosis and Treatment
- Health and Lifestyle Studies
- Parathyroid Disorders and Treatments
- Bone and Joint Diseases
- Oral health in cancer treatment
- Inflammasome and immune disorders
- Frailty in Older Adults
- Dermatological and COVID-19 studies
Hospital Regional Universitario de Málaga
2017-2024
Instituto Murciano de Investigación Biosanitaria
2024
Instituto de Investigación Biomédica de Málaga
2019-2023
Universidad de Málaga
2019-2023
Andalusian Centre for Nanomedicine and Biotechnology
2022-2023
Sociedad Española de Medicina Interna
2019
Background and aims Obesity is linked to elevated levels of inflammatory serum markers such as C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor alpha (TNFa). Adiponectin resistin are adipokines related obesity. It has been described that adipose tissue presents a high production secretion these diverse pro-inflammatory molecules, which may have local effects on the physiology fat cells well systemic other organs. Our aim was evaluate impact lifestyle modifications, by...
Introduction: The use of dipeptidyl peptidase-4 inhibitors in hospitalized patients is an area active research. We aimed to compare the efficacy and safety basal-bolus insulin regimen versus linagliptin-basal non-critically ill non-cardiac surgery a real-world setting. Methods: enrolled with type 2 diabetes departments admission glycated haemoglobin level < 8%, blood glucose concentration 240 mg/dL, no at-home injectable treatments who were treated (n = 347) or 190) regimens between January...
Background The impact of glucagon-like peptide-1 receptor agonists on patients with heart failure has not been fully described. Our main objective was to evaluate the safety and clinical glycemic efficacy once-weekly semaglutide in obese type 2 diabetes failure. Methods In this observational, retrospective, real-world study, we enrolled outpatients diabetes, obesity, who started were followed-up at 3, 6, 12 months. Results A total 136 included. From baseline months, there a significant...
(1) Background: Acute COVID-19 infections produce alterations in the skeletal muscle, leading to acute sarcopenia, but medium- and long-term consequences are still unknown. The aim of this study was evaluate: body composition; (2) muscle strength prevalence sarcopenia; (3) relationship between with symptomatic functional evolution older patients affected by/recovered from COVID-19; Methods: A prospective, longitudinal aged ≥65 years who had suffered infection 1 March 31 May 2020, as...
Abstract Background There is little evidence on the use of sodium−glucose cotransporter 2 (SGLT2) inhibitors in older patients with heart failure. This work analyzed clinical efficacy and safety empagliflozin continuation very old type diabetes hospitalized for acute decompensated Methods We conducted a real‐world observational study between September 2015 June 2021. Patients ≥80 years were grouped by antihyperglycemic regimen: (1) preadmission combined basal insulin regimen (2) conventional...
We aimed to develop and validate a prediction model, based on clinical history examination findings initial diagnosis of coronavirus disease 2019 (COVID-19), identify patients at risk critical outcomes.
Obesity, diabetes mellitus, and cardiovascular risk are real challenges in systemic lupus erythematosus (SLE) clinical practice research. The evidence of the burden these health problems SLE patients is determined by methods used to assess them. Therefore, aim this scoping review map current approaches assessing obesity, identify existing knowledge gaps field. This rapid was conducted according Joanna Briggs Institute methodology identified 274 articles, which 73 were included. Most studies...
Valproic acid (VPA) has shown beneficial effects in vitro against SARS-CoV-2 infection, but no study analyzed its efficacy the clinical setting.This multicenter, retrospective included 165 adult patients receiving VPA at time of admission to hospital, and 330 controls matched for sex, age date admission. A number clinical, outcome laboratory parameters were recorded evaluate differences between two groups. Four major endpoints considered: development lung infiltrates, in-hospital respiratory...
Background The individual influence of a variety comorbidities on COVID-19 patient outcomes has already been analyzed in previous works an isolated way. We aim to determine if different associations diseases the inpatients with COVID-19.Methods Retrospective cohort multicenter study based clinical practice. Data were taken from SEMI-COVID-19 Registry, which includes most consecutive patients confirmed hospitalized and discharged Spain. Two machine learning algorithms applied order classify...
Summary Background There are few studies that have analyzed the characteristics of hypercalcemia in hospitalized oncological patients. Our objectives were to describe clinical patients with paraneoplastic and identify prognostic variables for mortality. Methods This was an observational, longitudinal, retrospective, bicentric study. It included adult admitted two hospitals Málaga, Spain (2014–2018). The minimum follow-up period 2 years or until death. Results A total 154 included; majority...
Arterial stiffness is linked with the development of cardiovascular and noncardiovascular diseases. In clinical practice, measurement carotid-femoral pulse wave velocity (cf-PWV) has become a widely used study for assessment risk in elderly population. Our aim was to evaluate whether maintaining healthy life, based on Mediterranean Diet (MedDiet) regular practice physical activity, are associated arterial an elderly, metabolically overweight or obesity (MHOe) population.A transversal,...
OPINION article Front. Endocrinol., 03 April 2023Sec. Clinical Diabetes Volume 14 - 2023 | https://doi.org/10.3389/fendo.2023.1125961
There is little evidence on the use of sodium−glucose cotransporter 2 inhibitors in hospitalised patients. This work aims to analyse glycaemic and clinical efficacy safety empagliflozin continuation patients with type diabetes for acute decompensated heart failure. real-world observational study includes treated using our in-hospital antihyperglycaemic regimens (basal-bolus insulin vs. empagliflozin-basal insulin) between 2017 2020. A propensity matching analysis was used match a patient one...
Our objective was to compare clinical protocols for the treatment of novel coronavirus disease 2019 (COVID-19) among different hospitals in Andalusia, Spain. We reviewed current COVID-19 15 largest Andalusia. Antiviral treatment, empirical antibacterial agents, adjunctive therapies, anticoagulant supportive care, hospital organization, and discharge recommendations were analyzed. All included latest updates as July 2020. Hydroxychloroquine monotherapy most frequent antiviral drug recommended...