- Functional Brain Connectivity Studies
- Bone Tumor Diagnosis and Treatments
- Psychosomatic Disorders and Their Treatments
- Sarcoma Diagnosis and Treatment
- Scoliosis diagnosis and treatment
- Bone and Joint Diseases
- Lymphoma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Advanced Neuroimaging Techniques and Applications
- Neuroscience and Neuropharmacology Research
- Neurological and metabolic disorders
- Colorectal Cancer Surgical Treatments
- EEG and Brain-Computer Interfaces
- Neuroscience of respiration and sleep
- Management of metastatic bone disease
- Ion channel regulation and function
- Spine and Intervertebral Disc Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Magnesium in Health and Disease
- Educational and Psychological Assessments
- Pregnancy-related medical research
- Automotive and Human Injury Biomechanics
- Histone Deacetylase Inhibitors Research
- Potassium and Related Disorders
- Sirtuins and Resveratrol in Medicine
Beijing Institute of Technology
2024
Chinese PLA General Hospital
2020-2023
Second Military Medical University
2018-2022
Weatherford College
2020
Second Affiliated Hospital of Zhejiang University
2011-2019
Qingdao Municipal Hospital
2017-2019
Qingdao University
2017-2018
Shanghai Changzheng Hospital
2018
Zhejiang University
2008-2015
Tongji Hospital
2014
Delusions of schizophrenia have been found to be associated with alterations some brain regions in structure and task-induced activation. However, the relationship between spontaneously occurring symptoms spontaneous activity remains unclear. In current study, 14 schizophrenic patients delusions healthy controls underwent a resting-state functional magnetic resonance imaging (RS-fMRI) scan. Patients were rated Positive Negative Syndrome Scale (PANSS) Characteristics Delusional Rating (CDRS)....
Activin A, an important member of transforming growth factor-β superfamily, is reported to inhibit proliferation mature hepatocyte. However, the effect activin A on hepatic progenitor cells not fully understood. To that end, we attempted evaluate potential role in regulation cell proliferation. Using 2-acetaminofluorene/partial hepatectomy model, expression decreased immediately after partial and then increased from 9th 15th day post surgery, which associated with attenuation oval inhibited...
<i>Objectives:</i> Personality disorder functioning styles might contribute to the inconclusive findings about alexithymic features in schizophrenia. We therefore studied relationship between alexithymia and personality paranoid <i>Methods:</i> administered Chinese versions of Toronto Alexithymia Scale (TAS-20), Parker Measure (PERM), Positive Negative Syndrome as well Hamilton Anxiety Depression Scales 60 schizophrenia patients healthy control subjects....
Primary central nervous system lymphoma (PCNSL) is a rare subtype of extranodal non‑Hodgkin lymphoma, which limited to the system. Few studies are available reporting psychiatric symptoms as initial and dominant presentation PCNSL. The current study reports case PCNSL patient with history major depressive disorder coexisting rheumatoid arthritis (treated methotrexate), who initially presented recurrent that showed no response antidepressant drug therapy. Magnetic resonance imaging revealed...
Lithium intoxication can cause serious cardiac toxicity and is associated with electrocardiogram (ECG) changes. This paper described a case of 76-year-old man who was lithium intoxicated showed variety ECG abnormalities including sinus bradycardia, rapid atrial fibrillation, second-degree atrioventricular block T wave We monitored his ECGs during the after 3 days consecutively. After hemodialysis, partially eased along serum concentration decreased.
OBJECTIVE The objective of this study was to investigate the effect long-term bisphosphonate treatment on reducing local recurrence sacral giant cell tumors (GCTs) after nerve-sparing surgery. METHODS Thirty-five consecutive patients with GCTs who received in Shanghai Changzheng Hospital between January 2000 and December 2010 were included study. Between 2007 2010, 19 bisphosphonates following Before 2007, 16 surgery alone, these cases as control group. difference clinical data groups...
Osteosarcoma is a mesenchymally derived, high-grade bone sarcoma that the most frequently diagnosed primary malignant tumor. Today, chemoprevention regarded as promising and realistic approach in prevention of human cancer. Previous studies have suggested ellagic acid (EA) Sennoside B potential this regard. The aim present study was to elucidate anti-osteosarcoma effects EA by using Saos-2 MG63 osteosarcoma cells. It identified or treatment could inhibit growth, migration invasion cells,...
This study was to investigate the association of psychological characteristics and functional dyspepsia treatment outcome. 109 patients who met criteria for FD were enrolled. Eysenck Personality Questionnaire (EPQ), Symptom Checklist 90 (SCL90), Pittsburgh Sleep Quality Index (PSQI) used measure personality, symptoms, sleep quality in our patients. Leeds Dyspepsia (LDQ) assess dyspeptic symptoms at baseline after eight weeks treatment. The LDQ scores change therapy, degraded rate prognosis...
Osteosarcoma (OS) is a sarcoma with high rates of pulmonary metastases and mortality. The mechanisms underlying tumour generation development in OS are not well-understood. Haematopoietic cell kinase (HCK), vital member the Src family proteins, plays crucial roles cancer progression may act as an anticancer target; however, mechanism by which HCK enhances remains unexplored. Therefore, we investigated role vitro vivo. Downregulation attenuated proliferation, migration invasion increased...
Idiopathic basal ganglia calcification (IBGC) is a rare neurodegenerative disorder characterized by the deposition of calcium in brain and variable combinations movement disorders, gait impairment neuropsychiatric symptoms. Few reports have described psychiatric manifestations as early symptoms IBGC. The present study case middle-aged man with schizophrenia-like psychosis obsessive-compulsive first response patient to olanzapine fluoxetine suggests that low-dose effective should be increased...
The surgical efficacy and prognostic outcomes of patients with unspecific malignant bone tumors (UMBTs) remain unclear. study is to address: 1) What are the clinicopathological features determinants for UMBTs? 2) Can a nomogram be developed clinicians predict short long-term individuals 3) Does surgery improve UMBT who received radiotherapy or chemotherapy after balancing confounding bias?400 were filtrated from Surveillance, Epidemiology, End Results database assess features, treatments,...
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Gitelman syndrome(GS) is a rare inherited tubular disorder which characterized by hypokalemia, metabolic alkalosis, hypomagnesemia, and hypocalciuria. Here, we report case of schizophrenia-like psychosis concomitant with GS related literatures are reviewed.An 18-year-old male patient 1-week history auditory hallucinations, sense insecurity, delusions reference feelings being followed controlled others unknown, insomnia was admitted to Psychiatry department in December, 2013. Hypokalemia...
Background Osteosarcoma (OS) is a highly metastatic primary bone malignancy, and the treatment options remain inadequate. Hence, exploring innovative natural medications required. Prunetin (PRU) an isoflavone that has been proven anticancer agent in numerous cancer cell lines. However, activity of PRU against OS remains uncertain. Materials Methods Here, we studied (20 25 µM) on human cells MG-63 investigated its latent mechanism. The cytotoxicity, intracellular ROS, metastasis, apoptosis,...
To compare the efficacy and safety of retaining posterior longitudinal ligament (PLL) with resecting PLL in inside-out percutaneous endoscopic transforaminal discectomy (PETD) surgery for lumbar disc herniation (LDH).A total 135 patients symptomatic LDH who were treated by PETD from January 2015 to 2017were included this retrospective analysis. There 38 males 30 females resection group (mean age = 52.40 ± 8.73 years) 35 32 retention 53.50 9.24 years). The visual analogue scale (VAS) score,...
Osteosarcoma (OS) is a primary malignant tumor of the bone characterized by poor prognosis due to chemotherapy resistance and high recurrence rates. DJ-1 (PARK7) known as an oncogene its abnormal expression related various types tumors. It was found in this study that upregulated closely correlated with OS patients promoting proliferation, migration cells vitro through regulating activity CDK4 but not oxidation mechanism or AKT pathway. The combination promoted RB phosphorylation, leading...