- Cerebrospinal fluid and hydrocephalus
- Total Knee Arthroplasty Outcomes
- Stress Responses and Cortisol
- Traumatic Brain Injury and Neurovascular Disturbances
- Tryptophan and brain disorders
- Knee injuries and reconstruction techniques
- Reproductive Physiology in Livestock
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurosurgical Procedures and Complications
- Fetal and Pediatric Neurological Disorders
- Orthopaedic implants and arthroplasty
- Pregnancy and preeclampsia studies
- Gestational Diabetes Research and Management
- Cardiac Health and Mental Health
- Neonatal and fetal brain pathology
- Intracerebral and Subarachnoid Hemorrhage Research
- Intensive Care Unit Cognitive Disorders
- Neonatal Respiratory Health Research
- Eicosanoids and Hypertension Pharmacology
- Sports injuries and prevention
- Genetic and phenotypic traits in livestock
- Intracranial Aneurysms: Treatment and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Fatty Acid Research and Health
- Spinal Dysraphism and Malformations
Queensland Children’s Hospital
2024-2025
The University of Queensland
2014-2025
James Cook University
2011-2025
Mayo Clinic
1999-2024
University of California, Los Angeles
2024
Princess Alexandra Hospital
2014-2024
Townsville Hospital
2021
Vanderbilt University Medical Center
2018
International Ice Hockey Federation
2017
University of California, San Francisco
2017
Background: Most surgeons believe that graft choice for anterior cruciate ligament (ACL) reconstruction is an important factor related to outcome; however, revision may be limited due previously used grafts. Hypotheses: Autograft use would result in increased sports function, activity level, and decreased osteoarthritis symptoms (as measured by validated patient-reported outcome instruments). failure reoperation rate 2 years after ACL reconstruction. Study Design: Cohort study; Level of...
OBJECTIVE Ventricular shunt insertion is a common procedure in pediatric neurosurgical practice. In many areas of medicine there push toward rationalization healthcare resources and reduction low-value tests or procedures. The intraoperative sampling CSF at the time one traditional aspect care that has not been rigorously evaluated. Additionally, role cell counts chemistry predicting dysfunction often discussed but poorly studied. A recent meta-analysis found correlation between elevated...
Two experiments were conducted to examine influences of dietary energy and insulin on ovulation rate patterns luteinizing hormone (LH), follicle stimulating (FSH), glucose, estradiol in gilts during 6 d before estrus. In Exp. 1, 36 given al-trenogest for 14 synchronize a factorial arrangement, fed one two levels (5,771 or 9,960 kcal metabolizable (ME)/d), porcine (0 .1 IU/kg body weight iv every h). Dietary treatments began 4 1 after the last day altrenogest, respectively, lasted until 24 h...
Background: While revision anterior cruciate ligament reconstruction (ACLR) can be performed to restore knee stability and improve patient activity levels, outcomes after this surgery are reported inferior those primary ACLR. Further reoperations ACLR have an even more profound effect on satisfaction outcomes. However, there is a current lack of information regarding the rate risk factors for subsequent Purpose: To report reoperations, procedures performed, reoperation 2 years Study Design:...
In Brief The optimal anesthetic technique for outpatient knee arthroscopy remains controversial. this study, we evaluated surgical operating conditions, patient satisfaction, recovery times, and postoperative analgesic requirements associated with psoas compartment block, general anesthetic, or spinal techniques. Sixty patients were randomized to receive a propofol/nitrous oxide/fentanyl anesthesia 6 mg of bupivacaine 15 μg fentanyl, block 40 mL 1.5% mepivacaine. All received IV ketorolac...
Background: The occurrence of physiologic knee hyperextension (HE) in the revision anterior cruciate ligament reconstruction (ACLR) population and its effect on outcomes have yet to be reported. Hypothesis/Purpose: prevalence HE ACLR 2-year outcome were studied with hypothesis that preoperative ≥5° is a risk factor for (ACL) graft rupture. Study Design: Cohort study; Level evidence, 2. Methods: Patients undergoing identified prospectively enrolled between 2006 2011. inclusion criteria...
The Australasian Shunt Registry was established in 2016 with the aim of providing safety and quality data addition to enhancing capacity for research improve health outcomes patients cerebrospinal fluid shunts. Queensland Children's Hospital is largest single contributor paediatric patient maintains an independent institutional shunt database. this study validate demographic captured by against that Data from database a sample same institution held were acquired period 1 January 2017 October...
OBJECTIVE Ventriculoperitoneal shunt insertion is the primary treatment for pediatric hydrocephalus and one of most common procedures performed in neurosurgery. However, value routine postoperative imaging remains controversial. Although some evidence suggests that provides a low yield after revision, its role following initial children has not been reported. Additionally, as baseline study altering rate longer-term revision rates unexplored. METHODS A retrospective review was conducted...
The process of neurogenesis in which new neurons are generated by proliferation and differentiation neural stem/progenitor cells (NSCs/NPCs) has been a topic intensive recent investigation. Investigations the factors regulate this have recently begun to include immune including cytokines, however class proteins designated as chemokines relatively neglected. Increasing evidence for novel brain-specific mechanisms beyond their classical chemotactic functions suggested that they may play role...
Inhibition of human platelet malonyldialdehyde (an indicator prostaglandin synthesis) in platelet-rich plasma, not found after 100 mg ethanol per ml vitro, was dose-related at 200, 400 and 750 ml.
Improved discharge planning and extension of care to the general unit for patients transferring from intensive may prevent readmission prolonged hospital stays. Morbidity, mortality, costs increase in readmitted patients.To evaluate clinical effectiveness a critical nursing outreach service facilitating providing follow-up areas.A before-and-after study design (with historical controls 6-month prospective intervention) was used ascertain differences outcomes, length stay, cost/benefit....
Quantitative magnetic resonance (qMR) can be used to measure macromolecules in tissues and is a potential method of observing early cartilage changes the development posttraumatic osteoarthritis. Hypothesis/Purpose: We hypothesized that specific patient surgical factors affecting matrix composition after anterior cruciate ligament (ACL) reconstruction (ACLR) detected using T1ρ T2 relaxation times. Our purpose was demonstrate this ability multicenter feasibility study.Case series; Level...