Jingchun Wu

ORCID: 0000-0003-3769-0853
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About
Contact & Profiles
Research Areas
  • Wheat and Barley Genetics and Pathology
  • Plant Disease Resistance and Genetics
  • Genetic Mapping and Diversity in Plants and Animals
  • Genetics and Plant Breeding
  • Yeasts and Rust Fungi Studies
  • Galectins and Cancer Biology
  • Protease and Inhibitor Mechanisms
  • Blood properties and coagulation
  • Genetics, Aging, and Longevity in Model Organisms
  • Animal Nutrition and Physiology
  • Signaling Pathways in Disease
  • Monoclonal and Polyclonal Antibodies Research
  • Genomics, phytochemicals, and oxidative stress
  • Cell Adhesion Molecules Research
  • Veterinary medicine and infectious diseases
  • Vascular anomalies and interventions
  • CRISPR and Genetic Engineering
  • Plant pathogens and resistance mechanisms
  • RNA and protein synthesis mechanisms
  • Blood transfusion and management
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Mycotoxins in Agriculture and Food
  • Lipid metabolism and biosynthesis
  • Nitrogen and Sulfur Effects on Brassica

Shandong Agricultural University
2023-2025

Chinese Academy of Agricultural Sciences
2014-2024

Institute of Crop Sciences
2020-2024

Anhui Agricultural University
2022

Shantou University
2016-2018

Shantou University Medical College
2016-2018

Chinese Academy of Sciences
2018

Guangzhou Institutes of Biomedicine and Health
2018

Oil Crops Research Institute
2014

LaunchPoint Technologies (United States)
2005-2006

Association mapping can quickly and efficiently dissect complex agronomic traits. Rapeseed is one of the most economically important polyploid oil crops, although its genome sequence not yet published. In this study, a recently developed 60K Brassica Infinium(®) SNP array was used to analyse an association panel with 472 accessions. The single-nucleotide polymorphisms (SNPs) were in silico mapped using 'pseudomolecules' representative rapeseed establish their hypothetical order perform seed...

10.1093/dnares/dsu002 article EN cc-by-nc DNA Research 2014-02-07

Genome-wide association studies have revealed an between coronary heart disease (CHD) and genetic variation on chromosome 13q34, with the lead single nucleotide polymorphism rs4773144 residing in COL4A2 gene this genomic region. We investigated functional effects of variant. Analyses primary cultures vascular smooth muscle cells (SMCs) endothelial (ECs) from different individuals showed a difference genotypes COL4A1 expression levels, being lowest G/G genotype, intermediate A/G highest A/A....

10.1371/journal.pgen.1006127 article EN cc-by PLoS Genetics 2016-07-07

Objective- Genome-wide association studies have revealed a robust between genetic variation on chromosome 15q26.1 and coronary artery disease (CAD) susceptibility; however, the underlying biological mechanism is still unknown. The lead CAD-associated variant (rs17514846) at this locus resides in FURIN gene. In advanced atherosclerotic plaques, furin expressed primarily macrophages. We investigated whether alters expression affects monocyte/macrophage behavior. Approach Results- A...

10.1161/atvbaha.118.311030 article EN cc-by-nc-nd Arteriosclerosis Thrombosis and Vascular Biology 2018-07-05

Abstract: Rational design of blood‐wetted devices requires a careful consideration shear‐induced trauma and activation blood elements. Critical levels shear exposure may be established in vitro through the use specifically designed to prescribe both magnitude duration exposure. However, it is exceptionally difficult create homogeneous shear‐exposure history by conventional means. This study was undertaken develop Blood Shearing Instrument (BSI) with an optimized flow path which localized...

10.1111/j.1525-1594.2005.29082.x article EN Artificial Organs 2005-05-31

Identification and accurate mapping of new resistance genes are essential for gene pyramiding in wheat breeding. The YrJ22 is a dominant stripe-rust-resistance located at the distal end chromosome 2AL, which was identified leading Chinese-wheat variety, Jimai 22, showing high to CYR32, prevalent race Puccinia striiformis tritici (Pst) China. In current study, 15 F1 2273 F2 plants derived from cross 22/Avocet S were used fine-mapping YrJ22. RNA-Seq resistant susceptible bulks (designated...

10.3390/plants11233244 article EN cc-by Plants 2022-11-25

CRISPR/Cpf1 system is a novel genomic editing tool. Because of its more sophisticated components, and lower off-target rate, it has the potential to become better gene-editing Previous reports showed that could work effectively in multiple species. But our data show AsCpf1 activity big difference different vertebrates. Using vitro experiments, we finally learned between species due temperature.

10.1101/272716 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2018-02-27

1. The toxicity of Fusarium mycotoxin deoxynivalenol in poultry feeding W.A. AWAD, K. GHAREEB, J. BÖHM World's Poultry Science Journal CrossRef

10.22358/jafs/67412/2004 article EN cc-by Journal of Animal and Feed Sciences 2004-04-09

Abstract Stripe rust, caused by Puccinia striiformis f. sp. tritici (PST), is a worldwide wheat disease that causes large losses in production. Fine mapping and cloning of resistance genes are important for accurate marker-assisted breeding. Here, we report the fine candidate gene analysis stripe rust YrZM175 Chinese cultivar Zhongmai 175. Fifteen F 1 , 7,325 2 plants 117 F2:3 lines derived from cross Avocet S/Zhongmai 175 were inoculated with PST race CYR32 at seedling stage greenhouse,...

10.21203/rs.3.rs-1537017/v1 preprint EN cc-by Research Square (Research Square) 2022-04-20

<title>Abstract</title> Stripe rust caused by Puccinia striiformis f. sp. tritici (Pst) is a devastating foliar disease of wheat. Chinese landrace wheat Baidatou has shown high resistance to broad spectrum <italic>Pst</italic> races at both the seedling and adult-plant stages for decades in Longnan region Gansu province, hotspot stripe epidemics. Here, we report fine mapping candidate gene analysis <italic>YrBDT</italic> Baidatou. Analysis F<sub>1</sub>, F<sub>2</sub> plants F<sub>2:3</sub>...

10.21203/rs.3.rs-3731662/v1 preprint EN cc-by Research Square (Research Square) 2023-12-27

Continued progress towards development of the PediaFlow™, a miniature maglev turbodynamic VAD for pediatric applications has entailed rigorous computational modeling and optimization. Subsystems have been tested in-vitro to validate calibrate models, thereby leading second series numerical The first-generation PediaFlow is 51mm in length with diameter 28mm. mass appx. 100gm. At nominal flow rate 0.5lpm, generating 110.0mmHg pressure rise, rotor speed 8,000 rpm, shaft power approximately 0.9W...

10.1097/00002480-200603000-00241 article EN ASAIO Journal 2006-03-01
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