A5050417193- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Neonatal Health and Biochemistry
- HIV Research and Treatment
- Respiratory viral infections research
- COVID-19 and healthcare impacts
- Influenza Virus Research Studies
- Disaster Response and Management
- Metabolism and Genetic Disorders
- HIV/AIDS drug development and treatment
- Respiratory Support and Mechanisms
- Child Nutrition and Feeding Issues
- Infection Control and Ventilation
- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Attention Deficit Hyperactivity Disorder
- Hemoglobinopathies and Related Disorders
- Autism Spectrum Disorder Research
- Nosocomial Infections in ICU
- Homelessness and Social Issues
- SARS-CoV-2 detection and testing
- Thermal Regulation in Medicine
- Viral Infections and Outbreaks Research
- Otolaryngology and Infectious Diseases
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
University of Toronto
2005-2024
Public Health Ontario
2010-2024
Sunnybrook Health Science Centre
2023-2024
Health Sciences Centre
2023-2024
Lindsay Unified School District
2023
Manhattan Institute for Policy Research
2023
New York Proton Center
2023
Communities In Schools of Orange County
2023
Oregon Medical Research Center
2023
Public Health Agency of Canada
2005-2021
Background In the 2003 Toronto SARS outbreak, SARS-CoV was transmitted in hospitals despite adherence to infection control procedures. Considerable controversy resulted regarding which procedures and behaviours were associated with greatest risk of transmission. Methods A retrospective cohort study conducted identify factors for transmission during intubation from laboratory confirmed patients HCWs involved their care. All requiring outbreak identified. who provided care intubated treatment...
Abstract To determine factors that predispose or protect healthcare workers from severe acute respiratory syndrome (SARS), we conducted a retrospective cohort study among 43 nurses who worked in two Toronto critical care units with SARS patients. Eight of 32 entered patient’s room were infected. The probability infection was 6% per shift worked. Assisting during intubation, suctioning before and manipulating the oxygen mask high-risk activities. Consistently wearing (either surgical...
There are increasing concerns regarding the role of exposure to ambient air pollution during pregnancy in development early childhood cancers.This population based study examined whether prenatal and life (<1year age) exposures pollutants, including nitrogen dioxide (NO2) particulate matter with aerodynamic diameters ≤2.5μm (PM2.5), were associated selected common cancers Canada.2,350,898 singleton live births occurring between 1988 2012 identified province Ontario, Canada. We assigned...
Abstract Despite the fact that needle exchange was introduced in Vancouver as early 1988, sharing remains common. An analysis conducted to identify determinants of borrowing used needles among subjects participating a case‐control study. IDUs had documented HIV seroconversion after 1 January, 1994 (h = 89), or repeatedly tested HIV‐seronegative this date 192). Interviewer‐administered questionnaires focused on drug use, sexual behaviours, source and depression. Subjects were asked if they...
To identify determinants of HIV seroconversion among injection drug users (IDUs) during a period rising prevalence, case-control investigation was conducted. Cases were IDUs with new positive test after 1 January 1994, and negative within the prior 18 months. Controls required 2 tests same period. Subjects completed questionnaire on demographic, psychosocial, behavioural factors. Eighty-nine cases 192 controls similar respect to gender, age, ethnicity inter-test interval. Multivariate...
The objective of this study was to identify factors associated with frequent needle exchange program (NEP) attendance by injection drug users (IDUs) in Vancouver, Canada. Data were examined from a case control recent HIV infection. IDUs documented seroconversion after January 1, 1994 (n = 89) and seronegative controls two HIV-negative test results the same period 192) asked about demographic social information, sexual behavior, NEP attendance. Logistic regression used examine effect multiple...
The proportion of injection drug users (IDUs) testing positive for Human Immunodeficiency Virus (HIV) in British Columbia has increased from 3 to 7% since January 1993 (Patrick et al ., 1997). We conducted a qualitative study as first step case control investigation aimed at identifying risk factors associated with HIV seroconversion. Sixteen subjects participated in-depth interviews which were transcribed and analysed using grounded theory methods. Three dominant themes emerged: Addiction,...
Abstract Objective: To implement and evaluate a point-of-care (POC) molecular testing platform for respiratory viruses in congregate living settings (CLS). Design: Prospective quality improvement study. Setting: Seven CLS, including three nursing homes four independent-living facilities. Participants: Residents of CLS. Methods: A POC COVID-19, influenza B, syncytial virus was implemented at participating CLS from December 1, 2022 to April 15, 2023. with symptoms underwent paired testing,...
HIV transmitted drug resistance (TDR) surveillance is usually conducted by sampling from a large population. However, overall TDR prevalence results may be inaccurate for many individual clinical setting. We analyzed genotypes at tertiary care setting in Ottawa, Ontario order to evaluate local patterns among sub-populations.Genotyping reports were digitized ART naïve patients followed the Immunodeficiency Clinic Ottawa Hospital, between 2008 and 2010. Quality controlled, sequence data...
Abstract Objective: The ethical implications of infection prevention and control (IPAC) are recognized, yet a framework to guide the application principles is lacking. We adapted an provide systematic approach for fair transparent IPAC decision making. Methods: conducted literature search existing frameworks in IPAC. Working with practicing healthcare ethicists, was use Indications were developed practice, integration process conditions specifically relevant Practical refinements made based...
Abstract Late recognition of severe acute respiratory syndrome (SARS) was associated with no known SARS contact, hospitalization before the nosocomial outbreak recognized, symptom onset while hospitalized, wards clusters, and postoperative status. is difficult to recognize in hospitalized patients a variety underlying conditions absence epidemiologic links.
To estimate the minimum incidence of congenital Zika syndrome (CZS) and severe microcephaly in Canada describe key clinical, epidemiological, aetiological outcome features these conditions.Two separate national surveillance studies were conducted on CZS using well-established Canadian Paediatric Surveillance Program from 2016 to 2019. Over 2700 paediatricians across surveyed monthly asked report demographic details, pregnancy travel history, infant anthropometry, clinical laboratory findings...
Abstract We conducted a tabletop exercise on influenza outbreak preparedness that engaged large group of congregate living settings (CLS), with improvements in self-reported knowledge and readiness. This proactive approach to responding communicable disease threats has potential build infection prevention control capacity beyond COVID-19 the CLS sector.
Older adults residing in congregate living settings (CLS) such as nursing homes and independent facilities remain at increased risk of morbidity mortality from coronavirus disease 2019. We performed a prospective multicenter study consecutive severe acute respiratory virus 2 (SARS-CoV-2) exposures to identify predictors transmission this setting.