A5028819572- Malaria Research and Control
- Mosquito-borne diseases and control
- Global Maternal and Child Health
- HIV/AIDS drug development and treatment
- Parasites and Host Interactions
- Influenza Virus Research Studies
- Vibrio bacteria research studies
- Child Nutrition and Water Access
- Vaccine Coverage and Hesitancy
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Urban and Rural Development Challenges
- Pneumonia and Respiratory Infections
- Poverty, Education, and Child Welfare
- Respiratory viral infections research
- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Cassava research and cyanide
- Parasitic Diseases Research and Treatment
- Diagnosis and treatment of tuberculosis
- COVID-19 epidemiological studies
- Bacterial Infections and Vaccines
Ministry of Health
2009-2021
University of Zambia
2020
Beth Israel Deaconess Medical Center
2020
Association of Schools and Programs of Public Health
2020
World Health Organization - Pakistan
2020
University of Maryland, Baltimore
2020
Centers for Disease Control and Prevention
2020
Ministry of Health of the Russian Federation
2020
University Teaching Hospital
2020
Golden Valley Agricultural Research Trust
2020
Zambia national survey, administrative, health facility, and special study data were used to assess progress impact in malaria control between 2000 2008. financial support expanded from US$9 million 2003 US$ ~40 High prevention coverage was achieved extended poor rural areas. Increasing consistent time location with reductions child (age 6–59 months) parasitemia severe anemia (53% 68% reductions, respectively, 2006 2008) lower post-neonatal infant 1–4 years of age mortality (38% 36% 2001/2...
In line with the Global trend to improve malaria control efforts a major campaign of insecticide treated net distribution was initiated in 1999 and indoor residual spraying DDT or pyrethroids reintroduced 2000 Zambia. 2006, these were strengthened by President's Malaria Initiative. This manuscript reports on monitoring evaluation activities potential impact emerging resistance disease transmission.Mosquitoes captured daily through series 108 window exit traps located at 18 sentinel sites....
Background Tuberculosis in Zambia is a major public health problem, however the country does not have reliable baseline data on TB prevalence for impact measurement; therefore it was among priority countries identified by World Health Organization to conduct national survey Objective To estimate of tuberculosis adult Zambian population aged 15 years and above, 2013–2014. Methods A cross-sectional population-based conducted 66 clusters across all 10 provinces Zambia. Eligible participants...
Abstract Background The Zambia Malaria Indicator Survey (ZMIS) of 2006 was the first nation-wide malaria survey, which combined parasitological data with other indicators such as net use, indoor residual spraying and household related aspects. survey carried out by Zambian Ministry Health partners objective estimating coverage interventions burden in children less than five years. In this study, ZMIS were analysed order (i) to estimate an empirical high-resolution risk map country (ii)...
Zambia continues to make strides in reducing malaria burden through the use of proven interventions and has recently pledged eliminate by 2021. Case management services have been scaled up at community level with rapid diagnostic tests (RDTs) providing antigen-based detection falciparum only. Key national elimination goals is ability identify, treat all Plasmodium species. This study sought determine distribution non-falciparum assess performance for Western Southern Provinces Zambia, two...
Zambia has taken lead in implementing integrated malaria control so as to attain the National Health Strategic Plan goal of "reducing incidence by 75% and under-five mortality due 20% year 2010". The strategic interventions include use long-lasting insecticide-treated nets indoor residual spraying, artemisinin-based combination therapies (ACT) for treatment uncomplicated malaria, improving diagnostic capacity (both microscopy rapid tests), intermittent presumptive pregnant women, research,...
Lymphatic filariasis (LF) is a mosquito-borne disease, broadly endemic in Zambia, and targeted for elimination by mass drug administration (MDA) of albendazole diethylcarbamazine citrate (DEC) to at-risk populations. Anopheline mosquitoes are primary vectors LF Africa, it possible that the significant scale-up malaria vector control over past decade may have also impacted transmission, contributed decrease prevalence Zambia. We therefore aimed examine putative association between decreasing...
ABSTRACT In Zambia limited access to adequate water and sanitation is a key developmental challenge, particularly for rapidly expanding peri-urban areas. During 2016–2017, cross-sectional household survey was conducted among 12,500 households representing ~60,000 individuals assess the burden of diarrheal respiratory disease measure water, sanitation, hygiene (WASH) characteristics in Lusaka, Zambia. We found that socio-economic factors, including having an additional member, children <5...
<h3>Objective</h3> To identify the etiology of an outbreak spastic paraparesis among women and children in Western Province Zambia suspected to be konzo. <h3>Methods</h3> We conducted investigation individuals from Mongu District, Province, Zambia, who previously developed lower extremity weakness. Cases were classified with World Health Organization definition Active case finding was through door-to-door evaluation affected villages sensitization at local health clinics. Demographic,...
In April 2016, an emergency vaccination campaign using one dose of Oral Cholera Vaccine (OCV) was organized in response to a cholera outbreak that started Lusaka February 2016. December second round conducted, with the objective increasing duration protection, before high-risk period for transmission. We assessed coverage first and rounds OCV campaign.Vaccination estimated after each from sample selected targeted-areas cross-sectional survey establish status individuals recruited. The study...
Antimalarial resistance is an inevitable feature of control efforts and a key threat to achieving malaria elimination. Plasmodium falciparum, the deadliest several species causing human malaria, has developed essentially all antimalarials. This study sought investigate prevalence molecular markers associated with sulfadoxine-pyrimethamine (SP) artemether-lumefantrine (AL) in Southern Western provinces Zambia. SP used primarily for intermittent preventive treatment during pregnancy, while AL...
Anti-malarial resistance is, and continues to be a significant challenge in the fight against malaria threat achieving elimination. In Zambia, chloroquine (CQ), safe, affordable well-tolerated drug, was removed from use 2003 due high levels of evidenced with treatment failure. This study sought investigate prevalence markers Southern Western Provinces Zambia 14 years after withdrawal CQ.Data cross-sectional, all-age household survey, conducted during peak transmission season (April-May 2017)...
Abstract We conducted a matched case-control (MCC), test-negative (TNCC) and case-cohort study in 2016 Lusaka, Zambia, following mass vaccination campaign. Confirmed cholera cases served as all three designs. In the TNCC, control-subjects were with negative culture polymerase chain reaction results. Matched controls by age sex selected among neighbours of confirmed MCC study. For study, we recruited cohort randomly individuals living areas considered at-risk cholera. 211 suspected (66 145...
Malaria burden in Zambia has significantly declined over the last decade because of improved coverage several key malaria interventions (e.g., vector control, case management, bed net distributions, and enhanced surveillance/responses). Campaign-based mass drug administration (MDA) focal MDA (fMDA) were assessed a trial Southern Province, Zambia, to identify its utility elimination efforts. As part study, longitudinal cohort was visited tested (by PCR targeting 18s rRNA Plasmodium...
This article describes data on selected resistance markers for antimalarial drugs used in Zambia. Antimalarial drug has hindered the progress control and elimination of malaria. Blood samples were collected during a cross-sectional household survey, conducted peak malaria transmission, April to May 2017. Dried blood spots survey transported laboratory analysis. The analysed included polymerase chain reaction (PCR) followed by high resolution melt (HRM) mutations associated with...
Despite the availability of vaccines, invasive bacterial diseases remain a public health concern and cause childhood morbidity mortality. We investigated characteristics etiological agents causing meningitis in children <5 years pre- (2010-2012) post- (2014-2019) 10-valent pneumococcal conjugate vaccine (PCV10) introduction Zambia.