A5046583540- Sarcoidosis and Beryllium Toxicity Research
- Chemotherapy-induced cardiotoxicity and mitigation
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Psoriasis: Treatment and Pathogenesis
- Muscle metabolism and nutrition
- Medical Research and Treatments
- Rheumatoid Arthritis Research and Therapies
- SARS-CoV-2 and COVID-19 Research
- Gut microbiota and health
- Asthma and respiratory diseases
- Chemical Reactions and Isotopes
- Diet and metabolism studies
- Allergic Rhinitis and Sensitization
- COVID-19 Clinical Research Studies
- Respiratory and Cough-Related Research
- Transgenic Plants and Applications
- Neurological Disease Mechanisms and Treatments
- Perfectionism, Procrastination, Anxiety Studies
- Pomegranate: compositions and health benefits
- Medicinal Plants and Bioactive Compounds
- Cynara cardunculus studies
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- PARP inhibition in cancer therapy
Ministry of Agriculture and Rural Affairs
2024
Jimei University
2024
Tianjin University of Traditional Chinese Medicine
2023-2024
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2019-2024
Beijing University of Chinese Medicine
2023-2024
Peking University
2024
Peking University Third Hospital
2024
Nantong University
2024
First People’s Hospital of Jingmen
2020-2024
Jingchu University of Technology
2024
Abstract Background Social anxiety has been shown to affect college students’ academic performance. However, the role of social media addiction and engagement in this association is unclear. Methods A total 2661 students completed a self-report questionnaire including Liebowitz Anxiety Scale, Bergen Media Addiction Utrecht Student Work Engagement Scale for Students, grade point average. Hayes’ PROCESS macro SPSS was employed test serial mediation effect. Results indicated that negatively...
Four male pigs (Duroc × Landrace Yorkshire; average initial (mean ± SEM) BW = 22.5 1.1 kg), fitted with permanent catheters in the portal vein, ileal vein and carotid artery, were used a 4 Latin square experimental design to measure effect of dietary starch sources on net appearance glucose amino acids. Dietary resistant (RS), maize, sticky rice brown rice. Diets provided at 0730, 1530 2330 h during 6-day adjustment period 1-day collection period. On day 7 each period, blood samples...
Sarcoidosis is a multisystem inflammatory disease characterized by the development of Th1/Th17/regulatory T cells (Tregs)-related non-caseating granulomas. Phosphoinositide-3 kinases δ/γ (PI3Kδ/γ) play an important role in maintenance effective immunity, especially for Tregs homeostasis and stability. In present study, superoxide dismutase A (SodA) stimulation was used to establish sarcoidosis mouse model. The second immune stimulus accompanied CAL-101 (PI3Kδ inhibitor) or AS-605240 (PI3Kδ/γ...
The current experiment aimed to investigate the effects of lncRNA KCNQ1OT1 on proliferation, autophagy and drug resistance hepatocellular carcinoma cells, as well potential molecular mechanism. Hepatocellular SK-HEP-1 cells DDP resistant SK-HEP-1/DDP were treated with cisplatin (DDP) different concentrations (1 nmol/L, 2 4 8 16 nmol/L). survival rate was determined by CCK8 method. QRT-PCR used detect levels miR-338-3p in normal hepatocyte HH01, cell hepatoma cisplatin-resistant SK-HEP-1/DDP....
To explore the clinical characteristics of patients infected with SARS-CoV-2 nationwide, especially effect factors asymptomatic infection and disappearance symptoms. A total 66,448 COVID-19 in China who have been diagnosed by nucleic acid test or rapid antigen were surveyed online (December 24, 2022 to January 16, 2023). Our cross-sectional study used descriptive analyses binary Logistics regression model assess correlation between relative factors, including age, gender, pre-existing...
Aim . The RelB gene plays an important role in guiding the progression of arthritis. We have previously demonstrated that expression is decreased significantly bone marrow DCs CD38 -/- mice. In this study, we demonstrate cluster differentiation (CD38) could be a potentially therapeutic target for autoimmune Method Collagen-induced arthritis (CIA) models were generated with both wild-type (WT) C57BL/6 and maturation marrow-derived dendritic cells (DCs) from WT mice detected. Antigen-specific...
Abstract Sarcoidosis is a systemic granulomatous disease associated with Th1/ regulatory T cells (Treg) paradigm. PI3K/Akt signaling, critical for maintaining Treg's homeostasis, aberrantly activated in sarcoidosis patients. Here we tested the role of PI3K inhibitors, LY294002 and BKM120, immune modulation experimental pulmonary sarcoidosis, concerning Th1/Th17/Treg profile detected by fluorescence‐activated cell sorting analysis or quantitative polymerase chain reaction, as well effect on...
Supercritical carbon dioxide (SC‐CO 2 ) extraction is carried out to simultaneously increase yield of extracted oil and the content pentacyclic triterpenes from residual parts globe artichoke. Box‐Behnken design used a set comprehensive experiments. Single interactive effects four processing variables (pressure, temperature, time, particle size) are investigated by response surface methodology (RSM), which also establish regression model according synthesis score (PTs). On other hand,...
Type 1 diabetes (T1D) is a multiple factor autoimmune disease characterized by T cell-mediated immune destruction of islet β cells. Autologous hematopoietic stem cell transplantation (AHSCT) has been novel strategy for patients with new-onset T1D, but not those later diagnosis. Disturbance regulatory cells (Tregs) likely contributes to poor response after in later-stage T1D. Inhibition phosphoinositide 3-kinases (PI3K)/Akt signaling maintains Tregs' homeostasis.We built streptozotocin...