- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Fungal Infections and Studies
- HIV/AIDS drug development and treatment
- Trypanosoma species research and implications
- Adolescent Sexual and Reproductive Health
- Diabetes Management and Research
- Antifungal resistance and susceptibility
- HIV-related health complications and treatments
- Research on Leishmaniasis Studies
- Acute Myocardial Infarction Research
- HIV, Drug Use, Sexual Risk
- Diabetes and associated disorders
- Adolescent and Pediatric Healthcare
- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Orthopaedic implants and arthroplasty
- Streptococcal Infections and Treatments
- SARS-CoV-2 and COVID-19 Research
- Biomedical Ethics and Regulation
- Vascular Tumors and Angiosarcomas
- Botulinum Toxin and Related Neurological Disorders
- Meta-analysis and systematic reviews
- Sepsis Diagnosis and Treatment
- Infectious Diseases and Tuberculosis
University of Colorado Anschutz Medical Campus
2020-2024
University of Colorado Denver
2019-2024
Bristol University Press
2024
South Tyneside and Sunderland NHS Foundation Trust
2020
Amsterdam University Medical Centers
2019
Vrije Universiteit Amsterdam
2019
Emma Kinderziekenhuis
2019
Lewin Group (United States)
2009
<b><i>Background:</i></b> Late-onset sepsis (LOS) in preterm infants is a leading cause of mortality and morbidity. Timely recognition initiation antibiotics are important factors for improved outcomes. Identification risk could allow selection at an increased LOS. <b><i>Objectives:</i></b> The aim was to identify <b><i>Methods:</i></b> In this multicenter case-control study, born ≤30 weeks gestation were included 9...
In this article, we estimate national health care resource use and medical costs in 2007 associated with prediabetes (PD), defined as either fasting plasma glucose between 100 125 or oral tolerance test 140 200. We Poisson regression claims for an adult population continuously insured 2004 2006 to analyze patterns of by PD status. Combining rate ratios that reflect prevalence rates from the National Health Nutrition Examination Survey, calculate etiological fractions portion PD. The findings...
Abstract Background QUANTI-TAF aimed to establish tenofovir-diphosphate (TFV-DP)/emtricitabine-triphosphate (FTC-TP) adherence benchmarks in dried blood spots (DBS) for persons with human immunodeficiency virus (PWH) receiving tenofovir alafenamide/emtricitabine (TAF/FTC)–based antiretroviral therapy (ART). Methods For 16 weeks, PWH received TAF/FTC-based ART co-encapsulated an ingestible sensor directly measure cumulative (enrollment final visit) and 10-day adherence. At monthly visits,...
Objective: Diabetes mellitus (DM) is associated with lower antiretroviral (ART) drug exposure among persons HIV (PWH) compared to PWH without DM. The association between DM and virologic control in PWH, however, remains unknown. Methods: We included participants the Multicenter AIDS Cohort Study/Women's Interagency Study Combined (MWCCS) who had initiated ART 1999 2020 a suppressed viral load (≤200 copies/ml) within 1 year of initiation. frequency incident viremia (HIV-1 RNA >200 adult...
Cryptococcal meningitis (CM) is an opportunistic fungal infection associated with human immunodeficiency virus (HIV) and other forms of immunosuppression. We lack a clear understanding CM mortality among HIV-negative, non-transplant patients in the United States (US). This article compares clinical features outcomes across HIV status laboratory-confirmed CM.A retrospective cohort study was performed that included adult treated at academic tertiary hospital between January 2000 September...
We present two cases of Leishmania (V) panamensis in returning travelers from Central America successfully treated with miltefosine. The couple presented ulcerative skin lesions nonresponsive to antibiotics. Skin biopsy polymerase chain reaction (PCR) revealed L. panamensis. To prevent the development mucosal disease and avoid inconvenience parental therapy, we both patients oral suggest that miltefosine represents an important therapeutic alternative treatment cutaneous caused by preventing...
Objective: People living with HIV (PLWH) are longer and developing more non-AIDS comorbidities, which negatively impact antiretroviral therapy (ART) adherence. Tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) is a novel pharmacologic measure of cumulative ART adherence that predictive viral suppression future viremia. However, the relationship between comorbidities this unknown. We aimed to evaluate association 3 (diabetes mellitus (DM), hypertension, hyperlipidemia) TFV-DP DBS...
Abstract Background Skin and soft tissue infections (SSTIs) are very common bacterial infections. Numerous clinical trials have compared antibiotics for SSTI treatment. However, typically non-inferiority designs that give little insight as to which antibiotic classes superior efficacy. Methods We performed a systematic literature review network meta-analysis of published treatment trials. Using standardized key words, we searched PubMed Embase from 1/1/66 5/31/22. excluded on diabetic foot...
<h3>Aims</h3> HbA1c is an established marker of glycaemic control in diabetes mellitus. A high associated with greater risk diabetic ketoacidosis, avoidable hospital admissions and long-term complications. In line national recommendation our paediatric clinic has a 'high pathway' involving intensive support to improve patients whose ≥70mmol/mol. We evaluated the impact 'High on patient outcomes. <h3>Methods</h3> Medical notes 109 young people High programme from June 2015 2017 were reviewed...