A5063140909- Microtubule and mitosis dynamics
- Genetic and Kidney Cyst Diseases
- Inflammasome and immune disorders
- Machine Learning in Bioinformatics
- Functional Brain Connectivity Studies
- Cellular Mechanics and Interactions
- Plant and Fungal Interactions Research
- Epigenetics and DNA Methylation
- Research in Cotton Cultivation
- RNA and protein synthesis mechanisms
- Ubiquitin and proteasome pathways
- Forest, Soil, and Plant Ecology in China
- Sulfur Compounds in Biology
- Satellite Communication Systems
- Phagocytosis and Immune Regulation
- Micro and Nano Robotics
- Renal and related cancers
- Plant Genetic and Mutation Studies
- vaccines and immunoinformatics approaches
- Cancer Mechanisms and Therapy
- Fetal and Pediatric Neurological Disorders
- Surgical Simulation and Training
- Environmental Changes in China
- Glutathione Transferases and Polymorphisms
- Toxic Organic Pollutants Impact
Jining Medical University
2024-2025
First Affiliated Hospital of Guangdong Pharmaceutical University
2024-2025
North Carolina State University
2025
Southern Medical University
2024
Zhujiang Hospital
2024
Sinopec (China)
2023
Shandong Tumor Hospital
2022-2023
Shandong First Medical University
2022-2023
Third Affiliated Hospital of Nanchang University
2023
Nanchang University
2023
Abstract Background Increasing evidence suggests that immunotherapy, especially immune checkpoint inhibitors (ICIs), has the potential to facilitate long-term survival in various cancer besides prostate cancer. Emerging indicated pyroptosis, an immunogenic form of cell death, could trigger anti-tumor microenvironment and enhance effectiveness immunotherapy. Nevertheless, mechanism underlying regulation pyroptosis signaling remains unclear. Methods The differential expression human E3 ligases...
Abstract In this study we characterized a panel of 1,264 maize near-isogenic lines (NILs), developed from crosses between 18 diverse inbred and the recurrent parent B73, referred to as nested NILs (nNILs). 884 nNILs were genotyped using genotyping-by-sequencing (GBS). Subsequently, 24 these nNILs, all parental lines, re-genotyped high-density SNP chip. A novel pipeline for calling introgressions, which does not rely on knowing donor each nNIL, was based hidden Markov model (HMM) algorithm....
Acrylamide (ACR) is a chemical compound with severe neurotoxicity, genotoxicity, carcinogenicity and reproductive toxicity. Recent studies showed that ACR impairs the function of organs, e.g., epididymis testes. In vitro maturation mouse oocyte sensitive assay to identify potential hazard female fertility. The aim this study was evaluate adverse effects on nuclear cumulus cells apoptosis oocytes in vitro. Cumulus–oocyte complexes were incubated medium containing 0, 5, 10 20 μM ACR....
Background BANF1 is well known as a natural opponent of cyclic GMP-AMP synthase (cGAS) activity on genomic self-DNA. However, the roles in tumor immunity remain unclear. Here, we investigate possible impact antitumor and response to immunotherapy. Methods The Cancer Genome Atlas public data were analyzed evaluate relevance expression BANF1, patients’ survival immune cell infiltration. We monitored growth explored efficacy targeting tumor-intrinsic combination with anti-programmed death...
ABSTRACT Polychlorinated biphenyls (PCBs), as typical environmental estrogen disruptors, are a structurally‐related group of halogenated aromatic hydrocarbons that composed 209 isomers and present mixture in the environment. PCBs congener with different numbers positions chlorine atoms substituted on biphenyl moiety. Aroclor‐1254 is more than 60 PCB congeners. Previous studies have provided evidence severe negative effects reproductive functions, but spindle assembly during mouse oocyte...
Abstract 3,3′,4,4′,5‐Polychlorinated biphenyl (PCB126) is a persistent organic environmental pollutant which can affect various biological activities of organisms, such as immunity, neurological function, and reproduction. In our study, we aimed to investigate the effects PCB126 on granulosa cells (GCs). GCs were collected from ovaries in PMSG‐treated mice, after 24 hours culture. then incubated with 10 pg/mL, 100 ng/mL for another hours. Following these steps, exposed further...
As each type of satellite network has different link features, its data transmission must be designed based on features to improve the efficiency transferring. The navigation integrated services information (NISI) in a global system (GNSS) with inter-satellite links (ISLs) is studied by taking real situation communication into account. An on-demand computing and buffering centralized route strategy proposed dynamic grouping topology evolution law GNSS within which nodes are operated manner...
The tumor suppressor protein cylindromatosis (CYLD), as a microtubule-associated deubiquitinase, plays pivotal role in wide range of cellular activities, including innate immunity, cell division, and ciliogenesis. Structural characterization reveals small zinc-binding B-box inserted within the ubiquitin specific protease (USP) domain CYLD; however, exact for this module remains yet to be elucidated. Here we identify critical facilitating intermolecular interaction subcellular localization...
Abstract Stroke affecting the basal ganglia and thalamus can lead to language deficits. In addition lesion’s direct impact on processing, connectional diaschisis involving cortical-subcortical interactions also plays a critical role. This study investigated using “dynamic meta-networking framework of language” in patients with stroke, analyzing longitudinal resting-state fMRI data collected at 2 weeks (n = 32), 3 months 19), one year post-stroke 23). As expected, we observed dynamic...
BACKGROUND: The single-subject morphological network (SSMN) provides a new approach for constructing structural connectome. However, its clinical relevance in post-stroke deficits and recovery remains unexplored. METHODS: This study utilized high-resolution 3D T1-weighted images alongside behavioral cognitive assessments across multiple domains, including language, motor, memory, attention, collected at two weeks, three months, one year post-stroke. SSMN was constructed using the AAL atlas...
Rehabilitation of lower limb amputation in developing countries is quite challenging. Though there are basic to highly advanced prostheses available India, the set-up still facing difficulties countries. Prosthetic management difficult due lack availability and reduced affordability among low income populations. In this review we highlighted prosthetic rehabilitation status India. Currently, India advancing well field, but further studies required provide more evidence recommendation.
Alternative splicing (AS) is a mechanism for generating different gene transcripts (called isoforms) from the same genomic sequence. Accurate classification of alternative important understanding regulation. Although algorithms are applied to classify AS, accuracy these still unsatisfactory. In this paper, we propose new algorithm cassette exons and constitutive with existed features based on AdaBoost algorithm. Experimental results show that higher than current algorithms. The sensitivity...