A5034255126- Tracheal and airway disorders
- Bone Tissue Engineering Materials
- Pleural and Pulmonary Diseases
- vaccines and immunoinformatics approaches
- SARS-CoV-2 and COVID-19 Research
- CRISPR and Genetic Engineering
- Lung Cancer Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Graphene and Nanomaterials Applications
- Salivary Gland Tumors Diagnosis and Treatment
- Nanoparticle-Based Drug Delivery
- Inhalation and Respiratory Drug Delivery
- Hemostasis and retained surgical items
- 3D Printing in Biomedical Research
- Vascular Malformations and Hemangiomas
- Vascular Anomalies and Treatments
- Nerve injury and regeneration
- Bone health and treatments
- Congenital Anomalies and Fetal Surgery
- Ultrasound in Clinical Applications
- Periodontal Regeneration and Treatments
- Lymphatic Disorders and Treatments
- Lymphatic System and Diseases
- Head and Neck Anomalies
Jaipur Golden Hospital
2012-2024
University of Toronto
2020-2023
Lunenfeld-Tanenbaum Research Institute
2020-2023
Sharda University
2015-2022
Institute of Medical Sciences
2015-2022
ESIC Hospital
2015-2022
University of Cape Town
2022
Singhania University
2016-2022
Sinai Health System
2020
Kalpana Chawla Government Medical College and Hospital
2019
Blood vessels and nerve fibers are distributed throughout the entirety of skeletal tissue, play important roles during bone development fracture healing by supplying oxygen, nutrients, cells. However, despite successful mimetic materials that can replace damaged from a structural point view, most available biomaterials often do not induce sufficient formation blood nerves. In part, this is due to difficulty integrating regulating multiple tissue types within artificial materials, which...
Abstract The worldwide SARS-CoV-2 outbreak poses a serious challenge to human societies and economies. proteins orchestrate complex pathogenic mechanisms that underlie COVID-19 disease. Thus, understanding how viral polypeptides rewire host protein networks enables better-founded therapeutic research. In complement existing proteomic studies, in this study we define the first proximal interaction network of proteins, at whole proteome level cells. Applying proximity-dependent biotinylation...
Abstract The world is facing a global pandemic of COVID-19 caused by the SARS-CoV-2 coronavirus. Here we describe collection codon-optimized coding sequences for cloned into Gateway-compatible entry vectors, which enable rapid transfer variety expression and tagging vectors. freely available. We hope that widespread availability this resource will many subsequent molecular studies to better understand viral life cycle how block it.
Defects in hydroxymethylbilane synthase (HMBS) can cause acute intermittent porphyria (AIP), an neurological disease. Although sequencing-based diagnosis be definitive, ∼⅓ of clinical HMBS variants are missense variants, and most clinically reported designated as "variants uncertain significance" (VUSs). Using saturation mutagenesis, en masse selection, sequencing, we applied a multiplexed validated assay to both the erythroid-specific ubiquitous isoforms HMBS, obtaining confident functional...
Background/Objective: Differences in soft-tissue stiffness may provide for a quantitative assessment and detection technique pressure ulcers or deep-tissue injury. An ultrasound indentation system relatively convenient, simple, noninvasive method measurement of changes soft- tissue vivo.Methods: The Tissue Ultrasound Palpation System (TUPS) was used to quantitatively measure at different anatomical locations within between able-bodied persons individuals with chronic spinal cord injury...
Defects in hydroxymethylbilane synthase (HMBS) can cause Acute Intermittent Porphyria (AIP), an acute neurological disease. Although sequencing-based diagnosis be definitive, ~⅓ of clinical HMBS variants are missense variants, and most clinically-reported designated as "variants uncertain significance" (VUS). Using saturation mutagenesis, en masse selection, sequencing, we applied a multiplexed validated assay to both the erythroid-specific ubiquitous isoforms HMBS, obtaining confident...
There is limited data on the role of asymptomatic STIs (aSTIs) risk human immunodeficiency virus (HIV) acquisition in male genital tract (MGT). The impact foreskin removal lowering HIV well described, but molecular events leading to are unclear. Here, this pilot study, we show that urethral infection with Chlamydia trachomatis (CT) significantly impacts proteome composition. We developed and optimized a shotgun liquid chromatography coupled tandem mass spectrometry (MS)-based proteomics...
The term "cryotherapy" comes from the Greek cryo (κρύο) meaning cold, and therapy (θεραπεία) cure. Cryosurgery is application of extreme cold to destroy abnormal or diseased tissue. Carcinoid tumors lung are a fascinating but uncommon group pulmonary neoplasms. In past, these were grouped with benign less aggressive malignant tumors, namely bronchial adenomas. Recent studies have revealed that carcinoid most indolent form spectrum bronchopulmonary neuroendocrine that, at its extreme, include...
A 57-year-old male presented with complaints of chest pain for 8 months and swelling in upper anterior wall 2 months, which were gradually increasing. He had no history fever, trauma, weight loss, cough, or dyspnoea. His medical surgical past illnesses was unremarkable. On local examination, a big potato-like attached to the sternum [Figure 1] slightly raised temperature irregular margins observed. The consistency hard it freely mobile. Rest respiratory system examination normal. Examination...
Sir, Pleural manometry is the technique to measure pleural pressure either with water manometer or digital manometer. Under normal conditions, there a thin film of fluid in space. The secreted from parietal pleura as it supplied by systemic vessels and high-pressure system absorbed visceral pulmonary vessels, which operate at lower pressures. It also lymphatics pleurae, covering diaphragms mediastinal region. Total volume 0.26 ± 0.1/ml/kg cell counts 1500-2000/ml, macrophages 75%,...
ABSTRACT Medical Thoracoscopy (MT) is commonly performed by respiratory physicians for diagnostic as well therapeutic purposes. The aim of the study was to provide evidence-based information regarding all aspects MT, both a tool and aid pulmonologists across India. consensus-based guidelines were formulated based on multistep process using set 31 questions. A systematic search published randomized controlled clinical trials, open labelled studies, case reports from electronic databases, like...
Isometric muscle force measurement is a sensitive marker for motor function recovery in rat nerve repair models. Current methods of eliciting maximal isometric with stimulation cannot provide longitudinal data.We developed novel method measuring device designed to allow minimally invasive and plantar flexion force. This indirectly elicited was compared by direct 3 surgical models.The measured after sciatic transection followed parabolic trend. There postinjury decrease that continued until...
Fecopneumothorax is an unusual and uncommon cause of hydropneumothorax. It extremely rare pleural disease, with only 16 cases being reported from worldwide. Here we report, a 35-year-old, previously healthy man incidental Bochdalek hernia whose chest radiograph was misinterpreted as hydropneumothorax managed by intercostal drain. This leads to left colopleural fistula fecopneumothorax. The patient surgically recovered well. To the best our knowledge, this first case fecopneumothorax which...