- Thyroid Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Head and Neck Anomalies
- Salivary Gland Tumors Diagnosis and Treatment
- Cervical Cancer and HPV Research
- Thyroid and Parathyroid Surgery
- Peptidase Inhibition and Analysis
- AI in cancer detection
- Lung Cancer Diagnosis and Treatment
- Occupational and environmental lung diseases
- Colorectal Cancer Surgical Treatments
- Head and Neck Cancer Studies
- Ultrasound in Clinical Applications
- Cutaneous lymphoproliferative disorders research
- Fungal Infections and Studies
- Cancer Research and Treatments
- Chromatin Remodeling and Cancer
- Cleft Lip and Palate Research
- Colorectal Cancer Treatments and Studies
- Pituitary Gland Disorders and Treatments
- Myasthenia Gravis and Thymoma
- Genetic factors in colorectal cancer
- BRCA gene mutations in cancer
Peking University
2019-2025
Peking University Cancer Hospital
2019-2025
Qingdao University
2024
Affiliated Hospital of Qingdao University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
Xi'an Jiaotong University
2010
Objective The presence of central lymph node metastasis (CLNM) represents a critical determinant in ascertaining the necessity for surgical intervention patients with papillary thyroid microcarcinoma (PTMC). However, predominant current methodologies confirming status clinical practice are hampered by low predictive accuracy preoperative ultrasound examination and high risk fine needle aspiration (FNA). Consequently, objective this study is to investigate identify specific immunocytochemical...
Abstract Background The International System for Reporting Serous Fluid Cytopathology (TIS) was recently proposed. We retrospectively applied TIS recommendations reporting the cytological diagnosis of serous effusions and reported our experience. Methods All from January 2018 to September 2021 were retrieved database. Recategorization performed using classification, risk malignancy (ROM) calculated each category. In addition, on basis original we further subdivided category IV (suspicious...
Cytopathological examination is one of the main examinations for pleural effusion, and especially many patients with advanced cancer, effusion only accessible specimen establishing a pathological diagnosis. The lack cytopathologists high cost gene detection present opportunities application deep learning. In this retrospective analysis, data representing 1321 consecutive cases were collected. We trained evaluated our learning model based on several tasks, including diagnosis benign malignant...
Abstract Controversy exists regarding whether patients with low‐risk papillary thyroid microcarcinoma (PTMC) should undergo surgery or active surveillance; the inaccuracy of preoperative clinical lymph node status assessment is one primary factors contributing to controversy. It imperative accurately predict PTMC before surgery. We selected 208 fine‐needle aspiration (FNA) liquid‐based preparations as our research objects; all these instances underwent dissection and, aside from status, were...
To evaluate the diagnostic utility of The Bethesda System for Reporting Thyroid Cytology (TBSRTC) at Peking University Cancer Hospital, incidence noninvasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTP), and impact reclassification on cytopathological outcomes.We performed a retrospective study fine-needle aspiration (FNA) cases between April 2014 March 2019. FNA results were classified according to TBSRTC. Post-surgery histological findings followed up.A total...
A new molecular subtype classification was proposed for small-cell lung carcinoma (SCLC). We aimed to further validate the in various SCLC patient samples using immunohistochemistry (IHC) highlight its clinical significance.
Abstract Intrathyroidal thymic carcinoma is a malignant epithelial tumor of the thyroid gland with differentiation; it counterpart ectopic thymoma and histologically resembles carcinoma. Given its favorable prognostic course, preoperative cytological diagnosis important to distinguish this neoplasm from other more aggressive neoplasms that can have similar or overlapping cytomorphological features. However, there little information about cytology disease available in literature, even latest...
More and more evidence indicated that tumor deposit (TD) was significantly associated with local recurrence, distant metastasis (DM), poor prognosis for patients colorectal cancer (CRC). This study aims to explore the main clinical risk factors presence of TD in CRC no DM (CRC-NDM) prognostic TD-positive after surgery. The data CRC-NDM between 2010 2017 were extracted from Surveillance, Epidemiology, End Results (SEER) database. A logistic regression model used identify presence. Fine Gray's...
Abstract Background Primary cutaneous anaplastic large-cell lymphoma (PC-ALCL) is a rare T-cell belonging to the CD30 + lymphoproliferative disorders. The case of PC-ALCL in temporal region exceedingly rare. Herein, we report involving mimicking infratemporal space infection. Case presentation A 78-year-old woman presented maxillofacial surgery service with 6-month history swelling and pain left side her face. Laboratory investigations found an elevated C-reactive protein (CRP). Imaging...
Distinguishing aggressive pT1 papillary thyroid carcinomas (PTCs) from indolent PTCs before or during surgery is important. To the best of our knowledge, few reports in literature have examined value cytomorphologic features PTC as predictors aggressiveness.This retrospective study included 226 patients who underwent preoperative fine-needle aspiration cytology (FNAC) and at Peking University Cancer Hospital between January 2018 December 2019. Data on clinical characteristics pathological...
Abstract Background Endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA) is a minimally invasive technique for cytological and histological diagnosis. The objective of this study was to explore the role diagnosis in EBUS‐TBNAs. Methods Eight hundred thirteen consecutive cases performed EBUS‐TBNA with both diagnoses were retrospectively reviewed. All patients followed up clinical data. Results Before immunohistochemical examination, sensitivity, specificity, diagnostic...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Ren W, Zhao L, Guo Lu N, Cao J. The value of BAP1 immunocytochemistry and CDKN2A fluorescence in situ hybridization diagnosis serous effusion malignant mesothelioma an analysis the association between degree cell atypia results two auxiliary methods. Polish Journal Pathology. 2020;71(3):229-235. doi:10.5114/pjp.2020.99789. APA Ren, W., Zhao, L., Guo, Lu, N., & Cao, (2020). Pathology, 71(3), 229-235....
Abstract Background: The International System for Reporting Serous Fluid Cytopathology (TIS) was recently proposed. We retrospectively applied TIS recommendations reporting the cytological diagnosis of serous effusions and reported our experience. Methods: All from January 2018 to September 2021 were retrieved database. Recategorization performed using classification, risk malignancy (ROM) calculated each category, performance evaluation carried out among different samples (pleural,...