A5101648138- Gut microbiota and health
- Iron Metabolism and Disorders
- Animal Nutrition and Physiology
- Galectins and Cancer Biology
- Signaling Pathways in Disease
- Synthesis and Characterization of Heterocyclic Compounds
- Acupuncture Treatment Research Studies
- Cytokine Signaling Pathways and Interactions
- Atherosclerosis and Cardiovascular Diseases
- Ruminant Nutrition and Digestive Physiology
- Protein Tyrosine Phosphatases
- Diet and metabolism studies
- MicroRNA in disease regulation
- Curcumin's Biomedical Applications
- Dermatology and Skin Diseases
- Renal and related cancers
- Optimism, Hope, and Well-being
- Heme Oxygenase-1 and Carbon Monoxide
- Ubiquitin and proteasome pathways
- Cell death mechanisms and regulation
- ATP Synthase and ATPases Research
- Natural product bioactivities and synthesis
- Chemokine receptors and signaling
- Alcohol Consumption and Health Effects
- Probiotics and Fermented Foods
Shihezi University
2020-2025
Zhejiang University
2022-2024
Shanghai Changzheng Hospital
2023
Union Hospital
2021
Huazhong University of Science and Technology
2021
Chongqing Medical University
2004
Butyrate is thought to enhance intestinal mucosal homeostasis, but the detailed mechanism remains unclear. Therefore, further investigation on of butyrate regulation homeostasis was performed.This study used weaned piglets with similar metabolic function humans as a research model. The dietary supplemented 0.2% sodium group (0.2% S) and negative control (CON) were established detect effects growth performance, tissue morphology, barrier function, microbial community structure in...
The study investigated the impact of dietary montmorillonite on growth performance, intestinal mucosal barrier, and microbial community in weaned piglets with control group (CON) supplementation 0.2% (0.2% M). Compared CON group, M feed diet increased average daily gain (ADG) days 15–35 day 1–35 intake (ADFI) (0.05 < P 0.1). Besides, higher villus height duodenum jejunum lower crypt depth colon were revealed than ( 0.05). Moreover, V/C (ratio depth) was compared to that both from...
Background Heart pathological hypertrophy has been recognized as a predisposing risk factor for heart failure and arrhythmia. DUSP (dual‐specificity phosphatase) 26 is member of the family proteins, which significant effect on nonalcoholic fatty liver disease, neuroblastoma, glioma, so on. However, involvement DUSP26 in cardiac remains unclear. Methods Results Our study showed that expression was significantly increased mouse hearts response to pressure overload well angiotensin II–treated...
Iron homeostasis disorder is associated with the imbalance of lipid metabolism, while specific interaction remains unclear. In present study, we investigated effect a high-iron diet on metabolism in mice. The C57BL/6 mice were fed normal (WT) or (WT + Fe) for 12 weeks. We found that WT Fe group showed significant decrease body weight gain, fat and accumulation liver when compared group. Accordingly, serum total cholesterol triglyceride levels both reduced diet. Moreover, exhibited expression...
Abstract Heme oxygenase-1 (HO-1) catalyzes the first and rate-limiting enzymatic step of heme degradation, producing carbon monoxide, biliverdin, free iron. Most iron is derived from aged erythrocytes by decomposition heme, which happened mainly in macrophages. However, role HO-1 on metabolism function macrophage unclear. The present study investigated effect macrophages, explored inflammatory response, polarization, migration inducer Hemin or inhibitor zinc protoporphyrin was intravenously...
Iron overload can lead to oxidative stress and intestinal damage happens frequently during blood transfusions iron supplementation. However, how influences mucosa remains unknown. Here, the aim of current study was investigate effects on proliferation differentiation stem cells (ISCs). An mouse model established by intraperitoneal injection 120 mg/kg body weight dextran once a fortnight for duration 12 weeks, an enteroid produced treatment with 3 mM or 10 ferric ammonium citrate 24 h. We...
As one of the important treatments health care and anti-aging in traditional Chinese medicine (TCM), moxibustion has been proved to have effects scavenging free radicals, anti-oxidation, reducing inflammatory reaction, regulating immunity so on. Recent studies shown that intestinal microbiota affect process aging. The relationship between aging, is still unclear. In this study, we explored at Guanyuan (RN4) acupoint on microbiota, short-chain fatty acids immunological characteristics young...
Objective: To investigate the regulatory effect of curcumin on proliferation and apoptosis in human cervical carcinoma cell line HeLa vitro. Methods: Human Hela was cultured cells were treated with 10–50 µmol/L for 24–72 h growth inhibition rates measured by MTT method. Cell inspected electron microscopy. In addition, expression bcl-2, bcl-xl caspase-3 protein observed SP immunohistochemistry. Results: Curcumin inhibited a dose-depending manner. Peak subG1 appeared DNA histogram FCM. A...