- COVID-19 Clinical Research Studies
- Innovations in Medical Education
- Colorectal Cancer Surgical Treatments
- Long-Term Effects of COVID-19
- Nitric Oxide and Endothelin Effects
- Colorectal and Anal Carcinomas
- Regional Economics and Spatial Analysis
- Gastric Cancer Management and Outcomes
- SARS-CoV-2 and COVID-19 Research
- Gastrointestinal disorders and treatments
- Cardiovascular and exercise physiology
- Employment and Welfare Studies
- Hernia repair and management
- Empathy and Medical Education
- Diversity and Career in Medicine
- Breast Cancer Treatment Studies
- Cardiovascular Health and Disease Prevention
- Allergic Rhinitis and Sensitization
- Blood Pressure and Hypertension Studies
- Biliary and Gastrointestinal Fistulas
- Labor market dynamics and wage inequality
- Esophageal and GI Pathology
- Bacterial Infections and Vaccines
- Intensive Care Unit Cognitive Disorders
- Youth Education and Societal Dynamics
Beaumont Hospital
2013-2025
Swansea University
2025
University of Medicine and Health Sciences
2025
Ollscoil na Gaillimhe – University of Galway
2025
Royal College of Surgeons in Ireland
2019-2024
University of Copenhagen
2024
Penn State Milton S. Hershey Medical Center
2005-2024
Tallaght University Hospital
2024
Pennsylvania State University
2017-2023
Duke University
2023
The term C3 glomerulopathy describes renal disorders characterized by the presence of glomerular deposits composed in absence significant amounts Ig. On basis electron microscopy appearance, subsets include dense deposit disease (DDD) and glomerulonephritis (C3GN). full spectrum histologic change observed has yet to be defined pathologic predictors outcome within this patient population remain largely unknown. This study thus a large cohort identified clinicopathologic outcome.All patients...
Tidal energy is one of the most predictable and reliable renewable sources, capable generating significant amounts electricity in coming decades. Scientists, researchers, technology developers are working tirelessly to propel industry forward, employing next-generation innovative design strategies achieve future milestones affordable sustainable power generation. In this context, validation novel tidal turbine systems offers advantages developers, enabling them deploy devices at various...
Abstract Cannabidiol (CBD) is a major non-psychoactive cannabinoid that has been detected in environmental samples, but the ecotoxicological effects remain unknown. In this study, Lumbriculus variegatus are exposed to CBD, and its metabolites 7-hydroxy-cannabidiol (7-OH-CBD) 7-carboxy-cannabidiol (7-COOH-CBD). toxicity, tactile stimulation elicit stereotypical behaviours locomotor activity measured after 24-hour exposure of L. CBD metabolites. We also describe impacts on dorsal blood vessel...
Abstract Background Divergent estrogen receptor (ER) and HER2 status with breast cancer disease progression has important consequences for clinical management long-term survival. Molecular subtype expression is dynamic influenced by therapeutic intervention the metastatic environment. There remains however, a lack of data regarding mechanism switching subsequent consequences. Methods We undertook study neoadjuvant inhibitor treated patients (n=161) to determine consequence treatment...
Despite the popularity of dietary nitrate supplementation and growing evidence base its potential ergogenic vascular health benefits, there is no direct information about effects on exercising limb blood flow in humans. We hypothesized that acute from beetroot juice would augment increases forearm flow, as well progressive dilation brachial artery, during graded handgrip exercise healthy young men. In a randomized, double-blind, placebo-controlled crossover study, 12 (22 ± 2 years) men...
The onset of menopause and accompanying changes to ovarian hormones often precedes endothelial dysfunction in women. In particular, accelerated impairments macrovascular microvascular function coincide with the loss estrogen, as does impaired responses ischemia-reperfusion (IR) injury. healthy, early postmenopausal women (
Restriction fragment length polymorphism analyses of swine leucocyte antigen (SLA) class I genes were performed on 70 Duroc and 38 Hampshire boars from the 1986-87 national performance tests each breed in USA. Few inbred. Southern blotting hybridization procedures genomic DNA, isolated white blood cells, using PvuII endonuclease a major histocompatibility complex (MHC) probe. Durocs had an average 11 restriction fragments, with most common being 63% least appearing only one boar. 12 73%...
Summary Three patients developed methaemoglobinaemia after eating meat contaminated with excessive nitrites. Diagnosis was delayed in the first two mild cases but promptly made third most severely affected case.
Foreign body (FB) ingestion results in perforation 1% of cases and is associated with significant morbidity rarely mortality. Clinical presentation variable can present a diagnostic challenge. We report our experience management patient delayed sigmoid colon foreign as result dental plate. A 67 year old female attended the colorectal outpatient clinic following an incidental finding mass on computed tomography (CT) abdomen. Further investigation identified plate impacted thickened colon. On...