Ka‐Chun Un

ORCID: 0000-0003-3939-8952
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About
Contact & Profiles
Research Areas
  • Cardiac Valve Diseases and Treatments
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Infective Endocarditis Diagnosis and Management
  • Coronary Interventions and Diagnostics
  • Acute Myocardial Infarction Research
  • Cardiac electrophysiology and arrhythmias
  • Heart Failure Treatment and Management
  • Cardiac Structural Anomalies and Repair
  • Antiplatelet Therapy and Cardiovascular Diseases
  • S100 Proteins and Annexins
  • Cardiomyopathy and Myosin Studies
  • Long-Term Effects of COVID-19
  • Neuroblastoma Research and Treatments
  • COVID-19 Clinical Research Studies
  • Ultrasound in Clinical Applications
  • Healthcare Decision-Making and Restraints
  • Neuroendocrine Tumor Research Advances
  • Non-Invasive Vital Sign Monitoring
  • Atrial Fibrillation Management and Outcomes
  • Blood Pressure and Hypertension Studies
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Thyroid and Parathyroid Surgery
  • Simulation-Based Education in Healthcare
  • Cardiac Imaging and Diagnostics

Queen Mary Hospital
2013-2025

University of Hong Kong
2013-2025

Chinese University of Hong Kong
2021-2024

Evelina London Children's Healthcare
2024

Guy's and St Thomas' NHS Foundation Trust
2024

Keimyung University Dongsan Medical Center
2020

Keimyung University
2020

Grantham Hospital
2017

Polymer-free drug-coated stents provide superior clinical outcomes to bare-metal in patients at high bleeding risk who undergo percutaneous coronary intervention (PCI) and are treated with 1 month of dual antiplatelet therapy. Data on the use polymer-based drug-eluting stents, as compared polymer-free such limited.In an international, randomized, single-blind trial, we zotarolimus-eluting umirolimus-coated risk. After PCI, were therapy, followed by single The primary outcome was a safety...

10.1056/nejmoa1910021 article EN New England Journal of Medicine 2020-02-12

Patients infected with SARS-CoV-2 may deteriorate rapidly and therefore continuous monitoring is necessary. We conducted an observational study involving patients mild COVID-19 to explore the potentials of wearable biosensors machine learning-based analysis physiology parameters detect clinical deterioration. Thirty-four (median age: 32 years; male: 52.9%) from Queen Mary Hospital were recruited. The mean National Early Warning Score 2 (NEWS2) 0.59 ± 0.7. 1231 manual measurement performed...

10.1038/s41598-021-82771-7 article EN cc-by Scientific Reports 2021-02-23

Background A high proportion of COVID-19 patients were reported to have cardiac involvements. Data pertaining sequalae is urgent importance define subsequent surveillance. Methods We performed a systematic screening for 97 consecutive survivors including electrocardiogram (ECG), echocardiography, serum troponin and NT-proBNP assay 1–4 weeks after hospital discharge. Treadmill exercise test magnetic resonance imaging (CMR) according initial results. Results The mean age was 46.5 ± 18.6 years;...

10.1371/journal.pone.0246732 article EN cc-by PLoS ONE 2021-02-11

Little is known about the impact of provision handheld point-of-care ultrasound (POCUS) devices on physical examination skills medical students.We describe an educational initiative that comprised a POCUS workshop followed by allocation device to students for use over subsequent 8 weeks. They were encouraged scan patients and correlate their findings. A mobile instant messaging group discussion platform was set provide feedback from instructors. Physical assessed means clinical...

10.1136/postgradmedj-2020-137773 article EN Postgraduate Medical Journal 2020-10-14

Advanced neurology diseases including motor neuron disease (MND) are usually progressive life-limiting illness and could be devastating for patients, families caregivers. Although medical technologies, such as enteral feeding non-invasive ventilation, may prolong life expectancy of the their utilization prompts important ethical questions in regard to quality (QoL). Little attention had been paid on how ACP practice would practically help with patients suffering from different diseases. We...

10.21037/apm.2017.09.10 article EN Annals of Palliative Medicine 2017-11-20

Carcinoid heart disease is an important complication of neuroendocrine tumors that may lead to significant morbidity and mortality. Right-sided valve involvement with consequent dysfunction one the common manifestations. Patients often have multiple, comorbidities advanced metastatic and, as such, not be suitable for surgical replacement due excessive risk. Transcatheter using balloon-expandable valves has been mainstay management these patients, particularly stenotic lesions but there...

10.1002/ccd.31302 article EN Catheterization and Cardiovascular Interventions 2024-11-17

The prognostic implication of statin in tolerance (SI) those with stable CAD remains unclear. We hypothesized that SI is higher significance patients elevated high-sensitive cardiac troponin I (hs-cTnI). A total 952 from the prospective Hong Kong study who had complete clinical data, biomarker measurements and were prescribed therapy studied. identified 13 (1.4%) 125 (13.1%) partial SI, respectively. At baseline, more likely to have diabetes mellitus a hs-cTnI level, but no difference LDL-C...

10.1186/s12872-019-1152-x article EN cc-by BMC Cardiovascular Disorders 2019-07-15

Abstract Implementation of a critical care pathway (CCP) for acute coronary syndrome (ACS) has been shown to improve early compliance guideline-directed therapies and reduce mortality. Nevertheless its long-term impact on the with medications or clinical outcomes remains unknown. Between 2004 2015, 2023 consecutive patients were admitted our unit ACS. We retrospectively compared 628 versus 1059 (mean age 66.1 ± 13.3 years, 74% male) managed before after full implementation CCP. Compared...

10.1038/s41598-019-53348-2 article EN cc-by Scientific Reports 2019-11-14

A 47 year-old male with known history of mitral valve prolapse (MVP) presented to our emergency department palpitation, heart failure and hypotension.Electrocardiogram showed monomorphic ventricular tachycardia (VT) right bundle branch block pattern a superior axis.Echocardiogram dilated left ventricle ejection fraction 60%, A2 A3 severe posterolaterally directed regurgitation.Coronary angiogram was normal.Before consideration surgery implantable cardioverter-defibrillator (ICD) insertion,...

10.1093/ehjci/jez109.005 article EN European Heart Journal - Cardiovascular Imaging 2019-06-01

Transapical Neochord mitral valve repair has been proven to be a technically safe procedure correct primary regurgitation (MR). Recurrent MR due ruptured artificial chords is rare. Here, we present 2 cases of recurrent severe the detached or partially after procedure.

10.3389/fcvm.2022.985644 article EN cc-by Frontiers in Cardiovascular Medicine 2022-11-09
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