- Renal Transplantation Outcomes and Treatments
- Acute Kidney Injury Research
- Coronary Interventions and Diagnostics
- Kawasaki Disease and Coronary Complications
- Organ Donation and Transplantation
- Coronary Artery Anomalies
- Cardiovascular Issues in Pregnancy
- Aortic aneurysm repair treatments
- Health and Lifestyle Studies
- Heart Failure Treatment and Management
- Obesity, Physical Activity, Diet
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrest and Resuscitation
- Body Composition Measurement Techniques
- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Pharmacological Effects and Toxicity Studies
- Cytomegalovirus and herpesvirus research
- Chronic Kidney Disease and Diabetes
- Acute Myocardial Infarction Research
- Healthcare Policy and Management
- Neurological Complications and Syndromes
- Lymphatic System and Diseases
- Pregnancy and Medication Impact
- Sepsis Diagnosis and Treatment
University of California, San Francisco
2020-2025
University of Alberta
2013-2022
University of British Columbia
2020-2022
The University of Melbourne
2021
Medtronic (Ireland)
2020
University Health Network
2018-2019
Toronto General Hospital
2019
University of Toronto
2016-2018
Monash Medical Centre
2016
Medtronic (United States)
2013-2015
Polymer-free drug-coated stents provide superior clinical outcomes to bare-metal in patients at high bleeding risk who undergo percutaneous coronary intervention (PCI) and are treated with 1 month of dual antiplatelet therapy. Data on the use polymer-based drug-eluting stents, as compared polymer-free such limited.In an international, randomized, single-blind trial, we zotarolimus-eluting umirolimus-coated risk. After PCI, were therapy, followed by single The primary outcome was a safety...
Patients with acute kidney injury (AKI) are at an increased long-term risk of death. Effective strategies that improve outcomes in patients AKI unknown.To evaluate whether the use angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) after hospital discharge is associated better AKI.This retrospective cohort study used data from Alberta Kidney Disease Network population database to 46 253 adults 18 years older episode during a hospitalization between July...
Background— Heart failure is a common Emergency Department (ED) presentation but whether ED volume influences patient outcomes unknown. Methods and Results— Retrospective cohort of all adults presenting to 93 EDs between 1999 2009 with most responsible diagnosis heart (n=44 925 visits; mean age, 76.4 years). Cases seen in low-volume had less comorbidities were likely be hospitalized (54.5%) than those medium (61.8%; adjusted odds ratio [aOR] 1.16, [95% confidence interval {CI} 1.10–1.23]) or...
The risk-benefit ratio of angiotensin-converting enzyme inhibitor or angiotensin receptor blocker therapy after AKI may be altered due to concerns regarding recurrent AKI. We evaluated, in a prospective cohort, the association between use (versus nonuse) inhibitors/angiotensin blockers and subsequent risk other adverse outcomes hospitalizations with without
Abstract Limited data exist on the incidence and clinical outcomes of neutropenia among kidney transplant recipients. Our study included 572 adults who received a at University California, San Francisco Medical Center between 2012 2018, were CMV‐mismatched or had PRA ≥ 80%. Recipients with HIV, Hepatitis B C, primary non‐function excluded. Participants followed for least 1 year after transplantation. Neutropenia was defined as absolute neutrophil count < 1000 cells/μl. Cox proportional...
The incidence of acute kidney injury (AKI) in hospitalized patients is rising, and survivors are at high risk for cardiovascular events mortality. Effective strategies that improve long-term outcomes AKI unknown.
Transplant candidates may gain an advantage by traveling to receive care at a transplant center that have more favorable characteristics than their local center. Factors associated with longer travel distance for and whether the excess (ETD) is access transplantation or graft failure are unknown.
Background and objectives The optimal induction treatment in low–immune risk kidney transplant recipients is uncertain. We therefore investigated the use outcomes of immunosuppression a low-risk cohort patients who were well matched with their donor at HLA-A, -B, -DR, -DQB1 on basis serologic typing. Design, setting, participants, & measurements Our study was an observational first adult kidney-only United States recorded by Organ Procurement Transplant Network. Results Among 2976...
Bacteremia is an important complication after kidney transplantation. We examined bacteremia and its outcomes in a large cohort of transplant recipients. Kidney transplants from 1-Jul-2004 to 1-Dec-2014 at the Toronto General Hospital were eligible for study inclusion. was defined as two blood culture positives common skin contaminants or one positive other organisms. The cumulative incidence first estimated using Kaplan-Meier method, risk factors Cox proportional hazards model. graft...
There has recently been considerable interest in better understanding how blood pressure should be managed after an episode of hospitalized AKI, but there are scant data regarding the associations between measured AKI and subsequent adverse outcomes. We hypothesized that among survivors, higher three months hospital discharge would associated with worse also these outcomes similar those who survived non-AKI hospitalizations.We quantified systolic (SBP) observed was risks loss kidney...
Work integrated learning in the space of nursing informatics is a new concept Australian curriculum. This study examined students' experiences pilot clinical placement centered on electronic medical records, their use patient care and decision making. Students completed reflective diaries during four-week placement. Data was explored by thematic analysis. Emergent themes included: importance adequate training using EMR; impact EMR workflow care; shaping future career choices; forming...
The accuracy of different anthropometric indices to predict cardiovascular diseases is still debated in adolescent age groups and few data are available state Punjab India. We compared the factor loadings risk factors. A total 1530 boys girls, adolescents aged 10–18 years were recruited for present study identify Principal component analysis (PCFA) was applied extract orthogonal components from physiometric variables. Association between explained by loadings. PCFA reduced 14 factors 4...