- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Hormonal and reproductive studies
- Clinical practice guidelines implementation
- Cancer Immunotherapy and Biomarkers
- Renal and Vascular Pathologies
- Renal and related cancers
- Organ Donation and Transplantation
- Meta-analysis and systematic reviews
- Urological Disorders and Treatments
- Urologic and reproductive health conditions
- Urinary Tract Infections Management
- Pediatric Urology and Nephrology Studies
- Urinary Bladder and Prostate Research
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare cost, quality, practices
- Radiomics and Machine Learning in Medical Imaging
- Management of metastatic bone disease
- Cancer survivorship and care
- Medical and Health Sciences Research
- Bone health and treatments
- Advanced Neuroimaging Techniques and Applications
Friedrich-Alexander-Universität Erlangen-Nürnberg
2012-2025
Bayreuth Medical Center
2023-2025
Deutsche Gesellschaft für Urologie
2014-2024
Universitätsklinikum Erlangen
2014-2023
Bridgepoint (Germany)
2020-2023
Comprehensive Cancer Center Erlangen
2021-2023
University of Freiburg
2014
University Medical Center Freiburg
2011-2012
Institut für Medizinische Informatik, Biometrie und Epidemiologie
2011
University of Tübingen
2009
Oral anticancer drugs (eg, kinase inhibitors) play an important role in cancer therapy. However, considerable challenges regarding medication safety of oral have been reported. Randomized, controlled, multicenter studies on the impact intensified clinical pharmacological/pharmaceutical care patient and treatment perception are lacking.Patients were eligible for randomized, AMBORA study, if they newly started any approved 2001 or later without restriction to certain tumor entities. Patients...
Since the definition of different histologic subtypes urothelial carcinomas by World Health Organization (WHO) 2004 classification, description molecular features and clinical behavior these variants has gained more attention. We reviewed 205 tumor samples patients with locally advanced bladder cancer mainly treated within randomized AUO-AB05/95 trial radical cystectomy adjuvant cisplatin-based chemotherapy for subtypes. 178 UC, 18 plasmacytoid (PUC) 9 micropapillary (MPC) were identified....
The standard treatment for invasive bladder cancer is radical cystectomy. In selected patients, bladder-sparing therapy can be performed by transurethral resection (TURBT) and radio-chemotherapy (RCT) or radiotherapy (RT). Our published in vitro data suggest that the Neuropilin-2 (NRP2)/VEGF-C axis plays a role resistance. Therefore, we studied prognostic impact of NRP2 VEGF-C 247 patients (cN0M0) treated with TURBT RCT (n = 198) RT 49) follow-up time up to 15 years. A tissue microarray was...
By using diffusion tensor magnetic resonance imaging (DTI) and subsequent tractography, a perisylvian language network in the human left hemisphere recently has been identified connecting Brocas's Wernicke's areas directly (arcuate fasciculus) indirectly by pathway through inferior parietal cortex. Applying DTI tractography present study, we found similar three-way right of 12 healthy individuals: direct connection between superior temporal lateral frontal cortex running parallel with an...
Renal tubular epithelial cells of proximal and distal origin differ markedly in their physiological functions. Therefore, we hypothesized that they also capacity to undergo mesenchymal alterations.We used cultures freshly isolated primary human cells. To distinguish different took advantage the fact uniquely express N-cadherin instead E-cadherin as major cell-cell adhesion molecule. provoke alteration treated these cocultures with TGF-β for up 6 days. Within this time period, morphology was...
<i>Introduction:</i> Reporting guidelines aim to ensure adequate and complete reporting of clinical studies are an indispensable tool translate scientific results into practice. The extent which incorporated the author instructions journals publishing in field urology remained unclear. <i>Materials Methods:</i> We assessed uro-nephrological indexed ‘Journal Citation Reports 2009’. Two authors independently guidelines. evaluated additional information including whether...
Objectives (1) To assess endorsement of trial registration in author instructions urology-related journals and (2) to whether randomised controlled trials (RCTs) the field urology were effectively registered. Design Cross-sectional study published trials. Setting Journals publishing urology. Participants First, authors analysed 55 indexed 'Journal Citation Reports 2009' (12/2010). The divided these two groups: those requiring not mentioning as a precondition for publication. Second, chose...