A5021152910- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Urological Disorders and Treatments
- Kidney Stones and Urolithiasis Treatments
- Genital Health and Disease
- Bladder and Urothelial Cancer Treatments
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Urinary Bladder and Prostate Research
- Ureteral procedures and complications
- Pediatric Urology and Nephrology Studies
- Testicular diseases and treatments
- Neuroendocrine Tumor Research Advances
- Pelvic floor disorders treatments
- Advanced Radiotherapy Techniques
- Traumatic Ocular and Foreign Body Injuries
- Female Genital Mutilation/Cutting Issues
- Ethics and Legal Issues in Pediatric Healthcare
- Sexual function and dysfunction studies
- Economic and Financial Impacts of Cancer
- COVID-19 and healthcare impacts
- Urinary Tract Infections Management
- Health and Medical Studies
- Extracellular vesicles in disease
Nuremberg Hospital
2018-2024
Paracelsus Medizinische Privatuniversität
2018-2023
Heidelberg University
2015-2021
University Hospital Heidelberg
2015-2017
Chirurgische Universitätsklinik Heidelberg
2017
National Institute of Diabetes and Digestive and Kidney Diseases
2016
Multiparametric magnetic resonance imaging has an emerging role in prostate cancer diagnostics. In addition, clinical information is a reliable predictor of significant cancer. We analyzed whether the negative predictive value multiparametric to rule out could be improved using factors, especially specific antigen density.A total 1,040 consecutive men with suspicion underwent first, followed by transperineal systematic and imaging-transrectal ultrasound fusion guided biopsy. Logistic...
To analyse the detection rates of primary magnetic resonance imaging (MRI)-fusion transperineal prostate biopsy using combined targeted and systematic core distribution in three tertiary referral centres.
Harninkontinenz ist neben Störungen der erektilen Funktionsfähigkeit die häufigste Funktionseinschränkung nach radikaler Prostatektomie (RPE) beim Prostatakarzinom (PCa). Die deutsche S3-Leitlinie empfiehlt, Patienten über mögliche Auswirkungen Therapieoptionen zu informieren (darunter Inkontinenz). Allerdings liegen bislang nur ungenaue Daten zur Kontinenz aus Routineversorgung im deutschsprachigen Raum RPE vor, was Information erschwert. Ziel dieser Arbeit es, Häufigkeit und Ausprägung...
To validate, in an external cohort, three novel risk models, including the recently updated European Randomized Study of Screening for Prostate Cancer (ERSPC) calculator, that combine multiparametric magnetic resonance imaging (mpMRI) and clinical variables to predict clinically significant prostate cancer (PCa).We retrospectively analysed 307 men who underwent mpMRI prior transperineal ultrasound fusion biopsy between October 2015 July 2018 at two German centres. was rated by Imaging...
Neuroendocrine carcinomas of the prostate (NEPCs) are rare tumors with poor prognosis. While platinum and etoposide-based chemotherapy regimens (PE) commonly applied in first-line for advanced disease, evidence second-line therapy beyond is very limited.Retrospective analysis all patients NEPCs including mixed differentiation adenocarcinoma component well differentiated neuroendocrine (NETs, carcinoids) at two high-volume oncological centers between 12/2000 11/2017.Of 46 identified 39.1 %...
Certification as a prostate cancer center requires the offer of several supportive measures to patients undergoing radical prostatectomy (RP). However, it remains unclear how estimate relevance these and whether availability differs between certified centers (CERTs) non-certified (NCERTs). In 20 German urologic centers, survey comprising questions on 15 was sent 1000 at median months after RP. Additionally, were asked rate using four-item Likert scale. The aim this study compare ratings...
Serum prostate-specific antigen (PSA), its derivatives, and magnetic resonance tomography (MRI) lack sufficient specificity sensitivity for the prediction of risk reclassification prostate cancer (PCa) patients on active surveillance (AS). We investigated selected transcripts in urinary extracellular vesicles (uEV) from PCa AS to predict (defined by ISUP 1 with PSA > 10 ng/mL or 2-5 any level) control biopsy. Before biopsy, urine samples were prospectively collected 72 patients, whom 43%...
Due to new radiobiologic data, the International Commission on Radiological Protection recommends a dose limit of 20 mSv per year eye lens. Therefore, IAEA Basic Safety Standard and European council directive 2013/59/EURATOM require reduction annual from 150 mSv. Urologists are exposed an elevated radiation exposure in head region during fluoroscopic interventions, due commonly used overtable X-ray tubes rarely protection for head. Aim study was analyze real lens urologist various which...
Introduction After the outbreak of COVID-19 unprecedented changes in healthcare systems worldwide were necessary resulting a reduction urological capacities with postponements consultations and surgeries. Material methods An email was sent to 66 hospitals focus on robotic surgery (RS) including link questionnaire (e.g. bed/staff capacity, surgical caseload, protection measures during RS) that covered three time points: representative baseline week prior COVID-19, March 16th-22nd April...
<b><i>Introduction:</i></b> Ureteropelvic junction obstruction (UPJO) and the simultaneous presence of kidney calyx stones represent a challenge for renal surgery. We present novel technique treatment UPJO by robotic pyeloplasty in combination with percutaneous endoscopic flexible nephroscopy. <b><i>Patients Methods:</i></b> Between January 2018 February 2020, 4 patients were diagnosed pelvic or calyceal stones. was treated conventional...
Patient’s regret (PatR) concerning the choice of therapy represents a crucial endpoint for treatment evaluation after radical prostatectomy (RP) prostate cancer (PCA). This study aims to compare PatR following robot-assisted (RARP) and open surgical approach (ORP). A survey comprising perioperative-functional criteria was sent 1000 patients in 20 German centers at median 15 months RP. Surgery-related items were collected from participating centers. To calculate differences between...
We investigated differences in treatment outcomes following radical prostatectomy (RP) between certified centers (CCs) and noncertified (nCCs) within the IMPROVE study group.A validated survey assessing various factors, including stress urinary incontinence (SUI) decision regret (DR), was administered to 950 patients who underwent RP across 19 hospitals (12 CCs 7 nCCs) at a median follow-up of 15 months after (interquartile range: 11-20). The response rate 74%, with 703 participating, 480...
Background Incontinence and sexual dysfunction are long-lasting side effects after surgical treatment (radical prostatectomy, RP) of prostate cancer (PC). For an informed decision, physicians patients should discuss expected impairments. Therefore, this paper firstly aims to develop validate prognostic models that predict incontinence function PC one year RP secondly provide online decision making tool. Methods Observational cohorts treated between July 2016 March 2021 in Germany were used....
Male patients with metastatic germ cell tumors can be cured in up to 96% of cases depending on stage and IGCCCG prognosis group. Treatment relapse consists conventional or high-dose chemotherapy (HDCT) autologous stem transplantation (ASCT) combined local treatment modalities.Most were classified as poor risk according (n = 24; 52%) intermediate 12), high 16), very 9) at time first IPFSG criteria. In 67% 31) HDCT/ASCT was performed salvage for primary refractory disease following line...
Introduction: The aim of the study is to compare length hospital stay, transfusion rates, and re-intervention rates during hospitalization for transurethral resection prostate (TUR-P), open prostatectomy (OP), laser therapy (LT) surgical treatment benign prostatic obstruction (BPO). Methods: URO-Cert an organization, in which clinical data diseases from 2 university, 19 public, 3 private hospitals 270 office-based urologists are collected order document quality. Data on diagnostics, therapy,...
Zusammenfassung Hintergrund Gemäß einer aktuellen Metaanalyse zeigt in Europa jeder zweite Patient mit einem Peniskarzinom (PeK) eine Assoziation dem Humanen Papillomavirus (HPV). Es liegen keine Daten darüber vor, inwieweit UrologInnen die Häufigkeit dieser viralen Karzinogenese kennen. Methoden wurde ein 14-Items umfassender deutschsprachiger Survey erstellt und Q3/2018 einmalig an von 45 Kliniken Deutschland (n = 34), Österreich 8), der Schweiz 2) Italien/Südtirol 1) verschickt. Insgesamt...
Background: The purpose of this study was to retrospectively analyze the diagnostic accuracy magnetic resonance imaging (MRI) examinations scrotum in comparison with standard ultrasound (US) and histopathology. Methods: A retrospective multi-center analysis MRI performed between 06/2008 04/2021 conducted. Results: total n = 113 patients were included. 53 histopathologies available, 52.8% malignant 50.9% benign findings. Related histopathology, true negative, false positive, positive 4.1%,...
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