- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Medical and Health Sciences Research
- Renal and Vascular Pathologies
- Pediatric Urology and Nephrology Studies
- Bladder and Urothelial Cancer Treatments
- Polyomavirus and related diseases
- Pelvic floor disorders treatments
- Liver Disease and Transplantation
- Transplantation: Methods and Outcomes
- Viral-associated cancers and disorders
- Acute Kidney Injury Research
- Kidney Stones and Urolithiasis Treatments
- Renal Diseases and Glomerulopathies
- Prostate Cancer Treatment and Research
- Testicular diseases and treatments
- Prostate Cancer Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Biomedical Ethics and Regulation
- Urinary Tract Infections Management
- Renal cell carcinoma treatment
- Palliative Care and End-of-Life Issues
- Urological Disorders and Treatments
- Metabolism and Genetic Disorders
University Hospital Carl Gustav Carus
2014-2024
TU Dresden
2014-2024
Klinik und Poliklinik für Urologie
2015-2024
Klinik und Poliklinik für Kinder- und Jugendmedizin
2024
Goethe University Frankfurt
2022
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2022
Martha-Maria Hospital
2022
Augusta-Kranken-Anstalt
2022
University Hospital Frankfurt
2022
BackgroundIn the Eurotransplant Kidney Allocation System (ETKAS), transplant candidates can be considered for high-urgency (HU) status in case of life-threatening inability to undergo renal replacement therapy. Data on outcomes HU transplantation are sparse and benefit is controversial.
Abstract Purpose An abnormal lower urinary tract poses significant challenges for transplant surgeons. Besides the ureteral anastomosis to an ileal conduit, there are diverse complex reconstructive solutions. Due its rarity, standardization and teaching of diversion is extremely difficult. Methods The indications outcomes diversions after kidney transplantation (KT) were retrospectively investigated at eight urologic centers including a current follow-up. Results Of 37 patients with 21 (56%)...
Zusammenfassung Hintergrund Urogenitale Tumoren zählen zur den häufigsten soliden Malignomen nach Nierentransplantation (NTX). Fragestellung Es erfolgte die Erfassung von Inzidenz und Mortalität urogenitaler NTX im eigenen Patientengut Übertragung der Erkenntnisse in Bezug auf empfohlene Nachsorgenotwendigkeit -frequenz. Material Methode Durchführung einer retrospektiven monozentrischen Tumorerkrankungen allgemein Urogenitaltumoren spezifisch Patienten, zwischen 2010 bis 2020 eine am...
Normothermic machine perfusion (NMP) offers a unique opportunity to objectively assess donor organ quality. This study describes the evaluation of inulin clearance as potential marker for ex vivo function porcine kidneys during NMP. The assessment was performed in both from slaughterhouse pigs (n = 20) and laboratory setting 28). were exposed different warm ischemia times (WIT). After period static cold storage, underwent 4-hour NMP with autologous whole blood. Inulin clearance, hemodynamic...
Abstract Purpose To assess differences in the length of hospital stay (LOS) patients who present emergently versus electively for a symptomatic ureteral stone and to explore underlying risk factors. Methods Billing data were analyzed from with calculi at our department 2010 2021. Statistical analysis ( U t est, logistic regression) was performed. Results 2274 (72% male, 28% female) stones (mean age 52.9y). 1578 (69.4%) presented an emergency setting 696 (30.6%) electively. Arterial...
Abstract Purpose The Eurotransplant Senior program allocating grafts from donors ≥ 65 years to recipients aged has proven good results within the last 20 years. However, “old” are also allocated younger < years, and this outcome of “old for young” kidney transplantations (KT) still lacks detailed investigations. Methods All KT performed at four tertiary referral centers were retrospectively compared including a recent follow-up, stratifying (donor recipient years) vs. “very old 70 years)....
Stress urinary incontinence in men is predominantly iatrogenic after radical prostatectomy or transurethral interventions. Current studies show that there a deficit the availability of surgical therapy not only Germany. The aim this study to investigate more detail structural health care situation treatment male stress
Kidney transplant recipients (KTRs) have an increased risk of developing genitourinary cancers, including prostate cancer (PCa), which is expected to become more prevalent due aging KTR population. Thus, knowledge surgical outcomes, treatment PCa, within this unique cohort required.
Using ex vivo normothermic machine perfusion (NMP) with whole blood we assessed marginal porcine kidneys under reperfusion. The aim was to link measureable and clinical parameters the currently used visual assessment. This could serve as a baseline for standardized evaluation score identify potentially transplantable in future.
To identify potentially transplantable organs in a pool of marginal kidneys, 33 porcine slaughterhouse kidneys were perfused for 4 h with whole blood. During the normothermic perfusion, plasma, urine, and tissue samples taken. Several biomarkers tubule injury, endothelial activation, inflammatory response evaluated potential correlation macroscopic appearance, histology, filtration activity. Generally, biomarker levels increased during perfusion. TLR-4, EDN-1, NGAL not associated any...
Introduction To analyze contemporary treatment trends in bladder stone management Germany over a 15-year period. Methods We analyzed data from the nationwide German hospital billing database 2006 to 2020. The significance of changes time was evaluated via linear regression analysis. Results Total case numbers therapeutic interventions for lower urinary tract calculi increased 6,770 9,037 2020 (p<0.001). Transurethral cystolithotripsy (TUCL) predominant procedure with increasing 5,552...
Background: The purpose of this study was to retrospectively analyze the diagnostic accuracy magnetic resonance imaging (MRI) examinations scrotum in comparison with standard ultrasound (US) and histopathology. Methods: A retrospective multi-center analysis MRI performed between 06/2008 04/2021 conducted. Results: total n = 113 patients were included. 53 histopathologies available, 52.8% malignant 50.9% benign findings. Related histopathology, true negative, false positive, positive 4.1%,...
The symptomatic nephroptosis of a kidney transplant is rare and potentially fatal complication requires fast diagnosis treatment. In this report, we describe case in which intermittent hydronephrosis an increase the creatinine levels were leading symptoms nephroptosis. Moreover, diagnostic procedures successful minimal-invasive To our knowledge, first report with consecutive without complications perfusion solved approach.