A5053922377- Organ Donation and Transplantation
- Renal cell carcinoma treatment
- Renal Transplantation Outcomes and Treatments
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Renal and Vascular Pathologies
- Pediatric Urology and Nephrology Studies
- Bladder and Urothelial Cancer Treatments
- Minimally Invasive Surgical Techniques
- Pelvic floor disorders treatments
- Adrenal and Paraganglionic Tumors
- Organ Transplantation Techniques and Outcomes
- Ureteral procedures and complications
- Urinary Bladder and Prostate Research
- Urological Disorders and Treatments
- Cancer Cells and Metastasis
- Renal and related cancers
- Cancer Genomics and Diagnostics
- Pituitary Gland Disorders and Treatments
- Neurological Complications and Syndromes
- Cancer, Hypoxia, and Metabolism
- Kidney Stones and Urolithiasis Treatments
- Medical and Health Sciences Research
- Urologic and reproductive health conditions
- Cancer Immunotherapy and Biomarkers
Martin Luther University Halle-Wittenberg
2015-2025
Klinik und Poliklinik für Urologie
2014-2023
University Hospital in Halle
2014-2023
Azienda Ospedaliero Universitaria Maggiore della Carita
1996-2019
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
1996-2019
Ludwig-Maximilians-Universität München
1990-2015
Luther University
2011-2015
Azienda Ospedaliera Ospedale Maggiore
1996-2013
Cleveland Clinic
2011
Kidney Associates
2011
The 4 most active centers of the laparoscopy working group German Urologic Association collected data about complications associated with laparoscopic surgery in urology.At 2,407 laparoscopies or retroperitoneoscopies were performed as May 1998, including 776 for varicocelectomy, 259 cryptorchidism, 481 pelvic lymph node dissection, 351 nephrectomy/heminephrectomy renal pathology, 139 cyst resection, 58 ureteral procedures, 44 adrenalectomy, 41 nephropexy, lymphocele fenestration, 40...
No AccessJournal of UrologyClinical Urology: Original Articles1 Jul 1998LAPAROSCOPIC NEPHRECTOMY: THE EXPERIENCE OF LAPAROSCOPY WORKING GROUP GERMAN UROLOGIC ASSOCIATION JENS RASSWEILER, PAOLO FORNARA, MATHIAS WEBER, GUNTHER JANETSCHEK, DIRK FAHLENKAMP, THOMAS HENKEL, MANFRED BEER, WALTER STACKL, WIELAND BOECKMANN, FRANZ RECKER, ALEXANDER LAMPEL, CLAUS FISCHER, ULRICH HUMKE, and KURT MILLER RASSWEILERJENS RASSWEILER , FORNARAPAOLO FORNARA WEBERMATHIAS WEBER JANETSCHEKGUNTHER JANETSCHEK...
Purpose We conducted a prospectively randomized clinical trial to compare the efficacy of three outpatient therapy regimens in 341 patients with progressive metastatic renal cell carcinoma. Patients and Methods were stratified according known predictors subsequently randomly assigned. Treatment arms were: arm A (n = 132), subcutaneous interferon alfa-2a (sc-IFN-α-2a), interleukin-2 (sc-IL-2), intravenous (IV) fluorouracil; B 146): treatment combined per oral 13-cis-retinoic acid; C 63),...
We conducted a prospectively randomised clinical trial to investigate the role of adjuvant outpatient immunochemotherapy administered postoperatively in high-risk patients with renal cell carcinoma. In total, 203 carcinoma patients' status post radical tumour nephrectomy were stratified into three risk groups: extending vein/vena cava or invading beyond Gerota's fascia (pT3b/c pN0 pT4pN0), locoregional lymph node infiltration (pN+), and after complete resection relapse solitary metastasis...
Tumor-associated immune cells have been discussed as an essential factor for the prediction of outcome tumor patients. Lymphocyte-specific genes are associated with a favorable prognosis in colorectal cancer but poor survival renal cell carcinoma (RCC). Flow cytometric analyses combined immunohistochemistry were performed to study phenotypic profiles infiltrating lymphocytes (TIL) and frequency T macrophages RCC lesions. Data correlated clinicopathological parameters Comparing oncocytoma...
<h3>Importance</h3> DCVAC/PCa is an active cellular immunotherapy designed to initiate immune response against prostate cancer. <h3>Objective</h3> To evaluate the efficacy and safety of plus chemotherapy followed by maintenance treatment in patients with metastatic castration-resistant cancer (mCRPC). <h3>Design, Setting, Participants</h3> The VIABLE double-blind, parallel-group, placebo-controlled, phase 3 randomized clinical trial enrolled mCRPC among 177 hospital clinics US Europe between...
Open partial nephrectomy has emerged as the standard of care in management renal tumors smaller than 4 cm. While laparoscopic radical been shown to be comparable open with respect long-term outcomes, important questions remain unanswered regarding oncological efficacy nephrectomy. We examined practice patterns and pathological outcomes following nephrectomy.A survey was sent academic medical centers United States Europe performing The total number nephrectomies, positive margins, indications...
What's known on the subject? and What does study add? Surgical treatment options for male stress urinary incontinence (SUI) include collagen injection, artificial sphincter, or sling placement. In recent years, various minimally invasive systems have been investigated as post‐prostatectomy SUI. One of drawbacks using slings is lack ability to make postoperative adjustments. To overcome challenges associated with peri‐ adjustment systems, adjustable transobturator system (ATOMS®) was...
Objective To evaluate the long‐term effectiveness and safety of adjustable transobturator male system ( ATOMS ® , Agency for Medical Innovations A.M.I., Feldkirch, Austria) in a European‐wide multicentre setting. Patients Methods In all, 287 men with stress urinary incontinence SUI ) were treated device between June 2009 March 2016. Continence parameters (daily pad test/pad use), urodynamics (maximum flow rate, voiding volume, residual urine), pain/quality life (QoL) ratings (visual analogue...
Objectives To evaluate functional results, graft survival and late complications in patients who underwent robot‐assisted kidney transplantation ( RAKT ) had a minimum of 1 year follow‐up data, to analyse the correlations between surgical data results at 1‐year postoperatively renal function immediate postoperative period after year. Materials Methods A common prospectively collected database was created by European Robotic Urological Section ERUS working group, which included eight...
Objective To report the results of robot‐assisted kidney transplantation (RAKT) experience performed in 10 European centres by members Robotic Urology Section (ERUS)‐RAKT group. Patients and Methods This is a multicentre prospective observational study RAKT. Descriptive analysis recipients donor characteristics, surgical data, intraoperative outcomes, complications rate functional were collected analysed. Results Between July 2015 September 2019, 291 living‐donor RAKTs performed. Recipients...
Abstract Purpose: The aim of this study was to evaluate the clinical relevance presence disseminated tumor cells in peripheral blood (so-called circulating cells) for renal cell carcinoma patients. Methods: Two hundred thirty-three samples from 154 patients were investigated by autoMACS technique and immunocytochemical staining cytokeratin. frequency analyzed statistically correlation with relevant data. Results: kinds detected: those expression cytokeratin 8/18 (CK+) without a detectable...
What's known on the subject? and What does study add? Whereas open nephron‐sparing surgery ( NSS ) represents ‘gold standard’ in surgical therapy of T 1 renal tumours, with advances laparoscopic surgery, refinement intracorporeal suturing availability haemosealant substances, approach to is increasingly used. Laparoscopic partial nephrectomy LPN ), however, currently performed just a few high‐volume reference centres, its diffusion has been limited by steep learning curve. Conversely,...
To evaluate the safety and feasibility of laparoscopic adrenalectomy (LA) performed in several German centres with different experience, as LA has become gold-standard approach for benign surgical adrenal disorders; however, solitary metastasis or primary cancer its precise role is uncertain.The data 363 patients who underwent a were prospectively collected 23 centres. All stratified into three groups according to their experience: group A (<10 LAs/year), B (10-20 LAs/year) C (>20 LAs/year)....
Circulating tumor cells (CTCs) constitute a useful approach for personalized medicine. Nevertheless, the isolation of these remains very challenging because they rarely circulate in blood. Another current problem is cancer-specific characterization cells, which requires method that allows molecular and immunocytochemical profiling all captured cells. The purpose our proof concept study was to investigate use medical wire (CellCollector, GILUPI) isolate CTCs blood prostate cancer (PCa)...
We studied the association of serum levels microRNA family members miR-320a/-b/-c with clinico-pathological data to assess their applicability as diagnostic biomarker in prostate cancer (PCa) patients. The 3 groups were evaluated by qRT-PCR (145 patients PCa, 31 benign prostatic hyperplasia (BPH) and 19 healthy controls). three miR-320 directly correlated within each group (P < 0.001), but they differed significantly among 0.001). increased older compared younger (≤ 66 years vs. > years, P ≤...