- Respiratory viral infections research
- Salmonella and Campylobacter epidemiology
- Trace Elements in Health
- Parasites and Host Interactions
- Influenza Virus Research Studies
- Neuropeptides and Animal Physiology
- Ovarian function and disorders
- Cystic Fibrosis Research Advances
- Diabetic Foot Ulcer Assessment and Management
- Asthma and respiratory diseases
- Mesenchymal stem cell research
- Cytokine Signaling Pathways and Interactions
- Wound Healing and Treatments
- Cancer, Stress, Anesthesia, and Immune Response
- Mycobacterium research and diagnosis
- IL-33, ST2, and ILC Pathways
- Neonatal Respiratory Health Research
Central South University
2006-2023
Zhuzhou Central Hospital
2008-2022
University Hospital Heidelberg
2021
Heidelberg University
2021
Respiratory viral infections (RSV) can induce acute asthma attacks, thereby destroying lung function and accelerating the progression of disease. However, medications in stable phase are often not effective for attacks induced by infections. We aimed to clarify possible mechanism infection-induced through fatty acid metabolism.The airway resistances, inflammatory injuries, oxidative stress RSV-induced animal models were significantly higher than those control group at (7 days) chronic (28...
Objective. From our previous study, we obtained long noncoding RNA (lncRNA) STAT4-AS1, which is related to asthma through high-throughput screening. However, could not determine the specific mechanism involved and in response this. We further designed this study. Results. First, found that lncRNA STAT4-AS1 was downregulated T cells from patients with when compared healthy controls. Next, confirmed significantly negatively correlated helper 17 (TH17) differentiation vitro experiments. The...
Antibiotic inefficacy in treating bacterial infections is largely studied the context of developing resistance mechanisms. However, little attention has been paid to combined diseases mechanisms, interspecies pathogenesis and resulting impact on antimicrobial treatment. This review will consider co-infections Salmonella Schistosoma mansoni. It summarises protective mechanisms that pathophysiology two confer, which leads an antibiotic protection phenomenon. elucidate functional...
Many studies have shown that respiratory syncytial virus persistent infection may be the main cause of chronic pathology.However, mechanism is unclear. Cystic fibrosis transmembrane conduction regulator (CFTR) an apical membrane chloride channel, which very important for regulation epithelial fluid, ion, and bicarbonate transport. CFTR dysfunction will lead to changes in bronchial secretions impair mucus clearance, related airway inflammation. In our previous study, we observed...