A5031456893- Gut microbiota and health
- Respiratory viral infections research
- Child Nutrition and Water Access
- Diet and metabolism studies
- Bacterial biofilms and quorum sensing
- Epigenetics and DNA Methylation
- IL-33, ST2, and ILC Pathways
- Antibiotic Resistance in Bacteria
- Cancer, Hypoxia, and Metabolism
- Clostridium difficile and Clostridium perfringens research
- Global Maternal and Child Health
- interferon and immune responses
- Salmonella and Campylobacter epidemiology
- Bacteriophages and microbial interactions
- Birth, Development, and Health
- Pediatric health and respiratory diseases
- Health, Environment, Cognitive Aging
- RNA modifications and cancer
- Poxvirus research and outbreaks
- Neonatal Respiratory Health Research
- Lung Cancer Treatments and Mutations
- Maternal Mental Health During Pregnancy and Postpartum
- Mycobacterium research and diagnosis
- Dietary Effects on Health
- Trace Elements in Health
University of the Gambia
2018-2025
Central South University
2020-2025
Shandong First Medical University
2024-2025
Shandong Tumor Hospital
2024-2025
Xiangya Hospital Central South University
2020-2024
International Centre for Genetic Engineering and Biotechnology
2023
Ministry of Health and Social Welfare
2022
Federation University
2021
Ege University
2017-2018
Abstract Energy metabolism is a hub of governing all processes at cellular and organismal levels such as, on one hand, reparable vs. irreparable cell damage, fate (proliferation, survival, apoptosis, malignant transformation etc.), and, the other carcinogenesis, tumor development, progression metastazing versus anti-cancer protection cure. The orchestrator mitochondria who produce, store invest energy, conduct intracellular systemically relevant signals decisive for internal environmental...
Rapid deforestation and unprecedented wildlife trafficking are important factors triggering the rate of zoonotic spillover from animals to humans. Consequently, this leads emergence re-emergence infectious diseases among human population. Deforestation is an ecological disruption that loss biodiversity. The biodiversity results in persistence highest-quality hosts pathogens dominating low-diversity communities, a process termed dilution effect. Activities like intensive farming logging...
Respiratory viral infections (RSV) can induce acute asthma attacks, thereby destroying lung function and accelerating the progression of disease. However, medications in stable phase are often not effective for attacks induced by infections. We aimed to clarify possible mechanism infection-induced through fatty acid metabolism.The airway resistances, inflammatory injuries, oxidative stress RSV-induced animal models were significantly higher than those control group at (7 days) chronic (28...
The lung-brain axis is an emerging area of study that got its basis from the gut-brain biological pathway. Using Respiratory Synctial Virus (RSV) as model respiratory viral pathogen, this aims to establish some pathways. After establishing mice model, inflammation in lung and brain were assayed using Hematoxylin-eosin staining, indirect immunofluorescence (IFA), quantitative reverse-transcription polymerase chain reaction. pathways between detected through metabolomics analysis. In lung, RSV...
Monkeypox has been spreading worldwide since May 2022, when the World Health Organization (WHO) declared outbreak a "public health emergency of international concern." The spread monkeypox posed serious threat to people around world, but few studies have conducted, and molecular mechanism after infection remains unclear. We therefore implemented transcriptome analysis identify signaling pathways biomarkers in monkeypox-infected cells help understand monkeypox-host cell interactions. In this...
The adverse effects of maternal passive smoking during pregnancy on offspring health remain understudied in sub-Saharan Africa, particularly Gambia, where smoke-free regulations are limited. To determine the prevalence (MPS) and investigate its associations with outcomes complications Gambia. A cross-sectional study was conducted February 2023 among 401 mothers children under 5 years urban rural regions Data collected through structured interviews verification antenatal care records....
Lung adenocarcinoma (LA) is the main pathological type of lung cancer with a very low 5-year survival rate. In present study, after downloading mRNA, miRNA, and DNA methylation sequencing data from TCGA, combined downloaded clinical data, comparative analysis, prognostic GO KEGG GSEA transcriptional regulation post-transcriptional were performed. We found that both gene expression MNDA in LA down-regulated, while high was associated good overall LA. To probe mechanism, further analysis...
Abstract Both the epigenetic changes and gut microbiota (GM) have attracted a growing interest in establishing effective diagnostics potential therapeutic strategies for number of diseases. These disorders include metabolic, central nervous system‐related diseases, autoimmune, gastrointestinal infections (GI). Despite studies, there is no extensive review that connects epigenetics modifications GM as biomarkers could confer treatment options. To this end, hopes to give detailed information...
Abstract Background The human gut can be colonized by number of microorganisms. most studied are bacteria, which changes from birth to newborn born into adult-like microbiota. Much is known about the effects dietary, medications, and lifestyles on bacterial composition. However, host physiological influencing microbiota, immediate consequences, possible microbiota therapy not at length. This review based profoundly animal model studies through experimentation some clinical trials for past 20...
Abstract Background A number of previous studies have explored international students’ adaptation process with regards to language, lifestyle, food, and environment. However, there yet been no conducted address the menstrual symptoms challenges faced by female students during acculturation period. Thus, this study aims describe prevalence change explore influencing factors among studying in China Methods An online cross sectional was period (defined as first six months living host country)...