A5048788003- Viral Infections and Outbreaks Research
- Pluripotent Stem Cells Research
- CRISPR and Genetic Engineering
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Neural dynamics and brain function
- Disaster Response and Management
- Advanced MRI Techniques and Applications
- Viral Infections and Vectors
- Hepatitis B Virus Studies
- Evolutionary Psychology and Human Behavior
- Mosquito-borne diseases and control
- Hernia repair and management
- 3D Printing in Biomedical Research
- Viral gastroenteritis research and epidemiology
- Urological Disorders and Treatments
- Neurogenesis and neuroplasticity mechanisms
- Parasitic Infections and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Parasitic infections in humans and animals
- Renal and related cancers
- Neuroscience of respiration and sleep
- Immune responses and vaccinations
- Bacillus and Francisella bacterial research
- COVID-19 epidemiological studies
Inserm
2018-2024
Université Claude Bernard Lyon 1
2020-2024
Centre de Recherche en Neurosciences de Lyon
2021-2024
Centre National de la Recherche Scientifique
2021-2024
Délégation Régionale Auvergne-Rhône-Alpes
2021-2023
Le Laboratoire P4 Inserm Jean Mérieux
2023
Institut Cellule Souche et Cerveau
2020
Université de Strasbourg
2018
Institut des Sciences Cognitives
2017
Oxytocin (OT) concentration in the blood is considered to be a marker of its action brain. However, two problems have emerged when measuring OT level blood. First, it unclear whether different methods assessment lead similar values. Second, if plasma concentrations informative on what does To clarify these issues, we collected cerebrospinal fluid (CSF) from brain ventricle 25 patients during surgery compare with after simultaneous withdrawal. Additionally, 12 CSF and samples non-human...
A safe and protective Lassa virus vaccine is crucially needed in Western Africa to stem the recurrent outbreaks of infections Nigeria emergence previously unaffected countries, such as Benin Togo. Major challenges developing a include high diversity circulating strains their reemergence from 1 year another. To address each these challenges, we immunized cynomolgus monkeys with measles vector expressing glycoprotein nucleoprotein prototypic strain Josiah (MeV-NP). evaluate efficacy against...
Abstract Lassa fever hits West African countries annually in the absence of licensed vaccine to limit burden this viral hemorrhagic fever. We previously developed MeV-NP, a single-shot protecting cynomolgus monkeys against divergent strains one month or more than year before virus infection. Given limited dissemination area during outbreaks and risk nosocomial transmission, inducing rapid protection could be useful protect exposed people preventive vaccination. Here, we test whether time can...
After reprogramming to naive pluripotency, human pluripotent stem cells (PSCs) still exhibit very low ability make interspecies chimeras. Whether this is because they are inherently devoid of the attributes chimeric competency or PSCs cannot colonize embryos from distant species remains be elucidated. Here, we have used different types mouse, human, and rhesus monkey analyzed their rabbit cynomolgus embryos. Mouse embryonic (ESCs) remained mitotically active efficiently colonized host In...
Abstract A critical aspect of neuroscience is to establish whether and how brain networks evolved across primates. To date, most comparative studies have used resting-state functional magnetic resonance imaging (rs-fMRI) in anaesthetized nonhuman primates awake humans. However, anaesthesia strongly affects rs-fMRI signals. The present study investigated the impact awareness state (anaesthesia vs. awake) within same group macaque monkeys on connectivity organization a well-characterized...
The area of Lassa virus (LASV) circulation is expanding, with the emergence highly pathogenic new LASV lineages. Benin recently became an endemic country for and has seen a lineage (VII). first two outbreaks in 2014 2016 showed relatively high mortality rate compared to other outbreaks. We infected cynomolgus monkeys strains belonging II VII that were isolated from deceased patients during outbreak Benin. strain (L7) caused uniform mortality. Death was associated uncontrolled viral...
The functional organization of the frontal lobe is a source debate, focusing on broad subdivisions, large-scale networks, or local refined specificities. Multiple neurocognitive models have tried to explain how interactions between cingulate and lateral regions contribute decision making cognitive control, but their neuroanatomical bases remain unclear. We provide detailed description connectivity using resting-state MRI in rhesus macaques. analysis focuses rostral part sulcus with cortex....
Background : Several cases of infections due to Echinococcus multilocularis , Taenia martis and crassiceps were recently described in various species captive non-human primates (NHPs) harbored the Strasbourg Primate Center (SPC). Furthermore, one first human cysticercosis T. was region. These data suggest existence zoonotic cycles tapeworm direct environment SPC. The aim our study assess prevalence larval cestode among intermediate definitive hosts close neighborhood center. We analyzed...
Nous présentons un cas de hernie inguinale étranglée traité chirurgicalement chez macaque cynomolgus mâle. Le patient présentait choc sévère associé à gonflement l'aine et du scrotum droite. Une laparoscopie a permis mettre en évidence une indirecte, réduite par hernioplastie suivie d'une castration unilatérale la suture l'anneau inguinal. Après évaluation l'intégrité l'intestin, il été décidé ne pas réaliser d'entérectomie. récupéré l'intervention sans présenter complications. Bien que soit...
Summary After reprogramming to naïve pluripotency, human pluripotent stem cells (PSCs) still exhibit very low ability make interspecies chimeras. Whether this is because they are inherently devoid of the attributes chimeric competency or PSCs cannot colonize embryos from distant species remains be elucidated. Here, we have used different types mouse, and rhesus monkey analyzed their rabbit cynomolgus embryos. Mouse embryonic (ESCs) remained mitotically active efficiently colonized host In...
A bstract critical aspect of neuroscience is to establish whether and how brain networks evolved across primates. To date, most comparative studies have used resting-state functional Magnetic Resonance Imaging (rs-fMRI) in anaesthetized non-human primates awake humans. However, anaesthesia strongly affects rs-fMRI signals. The present study investigated the impact awareness state (anaesthesia vs. awake) within same group macaque monkeys on connectivity (FC) organization a well characterized...