A5100696145- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
- Mobile Health and mHealth Applications
- Bone fractures and treatments
- Pelvic and Acetabular Injuries
- MicroRNA in disease regulation
- Autism Spectrum Disorder Research
- Bone health and osteoporosis research
- Parkinson's Disease Mechanisms and Treatments
- Impact of Technology on Adolescents
- Liver Disease Diagnosis and Treatment
- Fungal Biology and Applications
- Phytochemicals and Antioxidant Activities
- Cancer-related molecular mechanisms research
- Vitamin D Research Studies
- Autophagy in Disease and Therapy
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Acupuncture Treatment Research Studies
- Orthopaedic implants and arthroplasty
- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Systemic Lupus Erythematosus Research
- Cell Adhesion Molecules Research
- Viral Infections and Immunology Research
- Bone Metabolism and Diseases
Beijing University of Chinese Medicine
2009-2025
Lanzhou Veterinary Research Institute
2021-2025
Chinese Academy of Agricultural Sciences
2021-2025
Lanzhou University
2025
Tianjin Medical University
2024
Tianjin Nankai Hospital
2024
Tianjin Medical University Cancer Institute and Hospital
2022-2023
Beijing Luhe Hospital Affiliated to Capital Medical University
2011-2023
Huazhong University of Science and Technology
2023
Peking Union Medical College Hospital
2023
Objectives To investigate vascular flow density in pathological myopia with optical coherence tomography (OCT) angiography. Design A prospective comparative study was conducted from December 2015 to March 2016. Setting Participants were recruited Beijing Tongren Hospital. total of 131 eyes enrolled, which divided into three groups: 45 emmetropia (EM; mean spherical equivalent (MSE) 0.50D −0.50D), 41 high (HM; MSE ≤−6.00D, without changes), and (PM; ≤−6.00D axial length (AL) ≥26.5 mm,...
Cordyceps sinensisis, a kind of precious natural crude drugs and edible mushrooms, were used as tonic food in East Asia area enjoyed an extensive praise for its medicinal functions. militaris, substitute C. sinensis, is widely distributed species, which can be cultivated various medium. In this study, the contents major bioactive components, cordycepin adenosine fruiting bodies mycelia from nature sinensis artificial cultural militaris investigated using improved HPLC method. The results...
ABSTRACT Foot-and-mouth disease virus (FMDV), a member of the Picornaviridae family, is single-stranded, positive-sense RNA virus. Heat shock protein A1 (HSPA1) has been shown to influence entry, translation, assembly, and release enterovirus A71 (EV-A71), another family member. In this study, we demonstrate that HSPA1 plays different role in replication FMDV. By investigating various stages replication, found specifically inhibits stage which viral by degrading RNA-dependent polymerase...
Boar taint is a major obstacle when using uncastrated male pigs for swine production. One of the main compounds causing this androstenone, pheromone produced in porcine testis. Here we use microarrays to study expression thousands genes simultaneously testis high and low androstenone boars. The allows identification pathways associated with elevated levels, which essential recognising potential molecular markers breeding purposes. Testicular tissue was collected from 60 boars, 30 extreme...
Objectives Hip fractures in elderly patients are associated with a high mortality rate. Most deaths hip fracture result from complications after surgery. Recent studies suggest that some inflammation biomarkers may be useful to estimate excess mortality. This study aimed investigate the prognostic value of admission fracture. Methods We reports on retrospective admitted hospital China between January 2015 and December 2019. A total 1085 were included study, their demographic pre‐operative...
With an increasing demand for postoperative cosmetic effects in breast diseases, the single port by trans-axillary incision and air-inflation system, which provided better space spared assistant effort of retraction, is widely used clinic surgical treatment multiple diseases.According to inclusion exclusion criteria, patients who underwent single-incision surgery at Tianjin Medical University Cancer Hospital between December 2020 July 2022 were included study. We collected analyzed data on...
Triclosan (TCS) is a broad-spectrum antimicrobial agent, whose well-known antibacterial mechanism inhibiting lipid synthesis. Autophagy, an innate immune response, intracellular process that delivers the cargo including pathogens to lysosomes for degradation. In this study, we first demonstrated TCS induced autophagy in dose-dependent manner nonphagocytic cells (HeLa) and macrophages (Raw264.7) vivo. The western blot results also revealed via AMPK/ULK1 JNK/ERK/p38 pathways independent of...
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disorder characterized by high autoantibodies levels and multiorgan tissue damage. The current study investigated the role of CD64 in SLE patients animal models. According to flow cytometry study, showed an increase expression circulating monocytes. There was correlation between SLEDAI, blood urea nitrogen levels, anti-Sm antibodies. In skin lesions MRL/ lpr mice, there IgG deposition expression. vitro , cytokines IL-10 IFN-γ...
Abstract Background Femoral neck shortening can occur in young patients receiving internal fixation for Pauwels type II femoral fracture. The risk factors shortening, which affect hip function, are not clear. This study aimed to retrospectively identify after with parallel partially threaded cannulated cancellous screws (FPTCS) fracture relatively patients. Methods Clinical data from 122 cases February 2014 2019 were reviewed and analyzed, causes of statistically analyzed. And the...
Glucocorticoid-induced osteoporosis (GIOP) is a severe and common complication of long-term usage glucocorticoids (GCs) lacks efficient therapy. Here, we investigated the mechanism anti-inflammation effect osteoclastogenesis side GCs immunoglobulin G (IgG) treatment against GIOP. inhibited SLE IgG-induced inflammation, while IgG GCs-induced osteoclastogenesis. FcγRI glucocorticoid receptor (GR) were found directly interacted with each other. could reduce expression on macrophages. The...
Osteoarthritis has the characteristics of degenerative changes in articular cartilage and secondary osteoporosis, it is a common chronic irreversible joint disease. In addition to affecting cartilage, subchondral bone, capsule synovial membrane also undergo pathological during development Multiple studies have revealed that patients with osteoarthritis were found significantly increased risk which contributes progression osteoarthritis. However, current existing studies, we no scholars used...
Background. Myocardial ischemia-reperfusion injury (MIRI) is characterized by its high incidence rate and mortality. miR-199a-3p thought to be strongly linked with the development of some myocardial diseases, but influence in MIRI remains unclear. Methods. AC16 cells were used. The concentrations mammalian target rapamycin (mTOR), light chain 3 II/light I, Beclin-1 detected western blotting qRT-PCR. binding site between mTOR was evaluated via luciferase report assay. Cell apoptosis through...
Abstract. Secondary aerosol is a major component of PM2.5, yet its formation mechanism in the ambient atmosphere still an open question. Based on field measurements downtown Beijing, we show that photolysis nitrous acid (HONO) could promote organic and nitrate wintertime Beijing as evidenced by growth mass concentration aerosols linearly increasing function consumed HONO from early morning to noon. The increased also lead particulate matter ammonium enhancing neutralization nitric ammonia....
To date, single-port laparoscopic pancreatic surgery has been rarely reported. This study aimed to evaluate the feasibility and safety of retroperitoneoscopic pancreatectomy based on first 3 cases in a single center. Three patients with suspected lesions distal pancreas underwent using conventional approach. All operations were successfully completed utilizing port. Operating times 50, 90, 150 minutes for cases. There no complications, all discharged within 7 days after surgery. In...
This study details our experience with an improved surgical technique involving the hepatic pedicle during laparoscopic left hemihepatectomy (LLH).We describe to extraparenchymally divide pedicle. A retrospective analysis of all patients who underwent liver procedures between 2002 and 2012 was conducted. The were divided into two groups, early LLH group (ELLH group) a recent (RLLH group), based on approach used for pedicle.A total 72 cases (26 ELLH 46 RLLH) identified. RLLH exhibited shorter...
Diabetes is considered an independent risk factor for hip fracture. In the present study, we evaluated whether perioperative glucose variability (GV) was a significant predictor of outcomes patients with diabetes after fracture.We analyzed characteristics and all fractures admitted to our hospital between September 2008 December 2012. Patients were grouped into tertiles GV, multivariate survival analysis included age, sex, fracture type, mean fasting plasma glucose, GV.Among 1099 in this 239...