Marike Geldenhuys

ORCID: 0000-0003-4005-118X
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About
Contact & Profiles
Research Areas
  • Viral Infections and Vectors
  • Bat Biology and Ecology Studies
  • SARS-CoV-2 and COVID-19 Research
  • Zoonotic diseases and public health
  • Rabies epidemiology and control
  • Animal Virus Infections Studies
  • Virology and Viral Diseases
  • Viral Infections and Outbreaks Research
  • Virus-based gene therapy research
  • Influenza Virus Research Studies
  • Species Distribution and Climate Change
  • Chromosomal and Genetic Variations
  • Mosquito-borne diseases and control
  • Microbial infections and disease research
  • Gamma-ray bursts and supernovae
  • COVID-19 epidemiological studies
  • Evolution and Paleontology Studies
  • Autopsy Techniques and Outcomes
  • Vector-Borne Animal Diseases
  • Streptococcal Infections and Treatments

University of Pretoria
2013-2025

Onderstepoort Veterinary Academic Hospital
1989

Species within the Neoromicia bat genus are abundant and widely distributed in Africa. It is common for these insectivorous bats to roost anthropogenic structures urban regions. Additionally, capensis have previously been identified as potential hosts Middle East respiratory syndrome (MERS)-related coronaviruses. This study aimed ascertain gastrointestinal virome of bats, viruses excreted fecal material or which may be replicating rectal intestinal tissues greatest opportunities coming into...

10.1371/journal.pone.0194527 article EN public-domain PLoS ONE 2018-03-26

A high diversity of corona- and paramyxoviruses have been detected in different bat species at study sites worldwide, including Africa, however no biosurveillance studies from Rwanda reported. In this study, samples bats collected caves Ruhengeri, Rwanda, were tested for the presence paramyxoviral RNA using reverse transcription PCR assays. Positive results further characterized by DNA sequencing phylogenetic analysis. addition to morphological identification species, we also did molecular...

10.3390/tropicalmed4030099 article EN cc-by Tropical Medicine and Infectious Disease 2019-07-02

Abstract Bat-borne viruses in the Henipavirus genus have been associated with zoonotic diseases of high morbidity and mortality Asia Australia. In Africa, Egyptian rousette bat species ( Rousettus aegyptiacus ) is an important viral host which -related sequences previously identified. We expanded these findings by assessing dynamics a southern African population. A longitudinal study henipavirus diversity excretion identified 18 putative circulating local population, three differing seasonal...

10.1038/s41598-021-03641-w article EN cc-by Scientific Reports 2021-12-20

Recent studies in several African countries have provided the first evidence for presence of coronaviruses bats. Here we describe, time, detection RNA 3 unique coronavirus species tissues South

10.1089/vbz.2012.1101 article EN Vector-Borne and Zoonotic Diseases 2013-03-08

In recent years, bats have been shown to host various novel bat-specific influenza viruses, including H17N10 and H18N11 in the Americas H9N2 subtype from Africa. Rousettus aegyptiacus (Egyptian Rousette bat) is recognized as a species for diverse viral agents. This study focused on molecular surveillance of maternal colony Limpopo, South Africa, between 2017–2018. A pan-influenza hemi-nested RT-PCR assay targeting PB1 gene was established, virus RNA identified one fecal sample out 860...

10.3390/v15020498 article EN cc-by Viruses 2023-02-10

Novel coronavirus species of public health and veterinary importance have emerged in the first two decades twenty-first century, with bats identified as natural hosts for progenitors many coronaviruses. Targeted wildlife surveillance is needed to identify factors involved viral perpetuation within host populations, drivers interspecies transmission. We monitored a colony Egyptian rousette at monthly intervals across years circulating coronaviruses, investigate shedding dynamics maintenance...

10.1038/s41598-023-42938-w article EN cc-by Scientific Reports 2023-09-22

Abstract Hosting 1460 plant and 126 vertebrate endemic species, the Great Escarpment (hereafter, Escarpment) forms a semi‐circular “amphitheater” of mountains girdling southern Africa from arid west to temperate east. Since biota are usually studied separately, earlier studies overlooked biogeographical importance as whole. Bats disperse more widely than other mammalian taxa, with related species intraspecific lineages occupying both highlands Escarpment, providing an excellent model address...

10.1111/gcb.17344 article EN cc-by Global Change Biology 2024-06-01

Mammarenaviruses are hosted by several rodent species, a small number of which have been known to be zoonotic. Host surveillance among mammals has identified large diversity previously undescribed mammarenaviruses. Intensified biosurveillance is warranted better understand the these agents. Longitudinal host involving non-volant at site in Limpopo province, South Africa, was conducted. The study reports on screening results 563 samples for presence mammarenavirus RNA. PCR-positive were...

10.3390/v15010099 article EN cc-by Viruses 2022-12-29

Purpose: Bats host a suite of pathogens and with several these, the route transmission to humans other animals is unknown. Factors such as availability food resources, age, reproductive status, movement behaviour population density have all been factors which effects risk infections within populations. In addition opportunistic short term surveillance, this study included longitudinal surveillance possibility seasonal variation pathogen prevalence. It also focus on presence in excretions...

10.1016/j.ijid.2016.11.154 article EN cc-by-nc-nd International Journal of Infectious Diseases 2016-12-01
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