Megan E. Griffiths

ORCID: 0000-0003-4130-9840
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About
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Research Areas
  • Ecology and Vegetation Dynamics Studies
  • Plant and animal studies
  • Rabies epidemiology and control
  • Bat Biology and Ecology Studies
  • Forest ecology and management
  • Plant Parasitism and Resistance
  • Seedling growth and survival studies
  • Viral Infections and Vectors
  • Cardiovascular and exercise physiology
  • Botany, Ecology, and Taxonomy Studies
  • Fire effects on ecosystems
  • Plant Diversity and Evolution
  • Coastal wetland ecosystem dynamics
  • Agroforestry and silvopastoral systems
  • Marine and coastal plant biology
  • Physical Activity and Health
  • Rangeland and Wildlife Management
  • Aeolian processes and effects
  • Acute Myocardial Infarction Research
  • Forest Management and Policy
  • Poxvirus research and outbreaks
  • Legume Nitrogen Fixing Symbiosis
  • Virology and Viral Diseases
  • Agronomic Practices and Intercropping Systems
  • Soil Carbon and Nitrogen Dynamics

MRC University of Glasgow Centre for Virus Research
2020-2025

University of Glasgow
2022-2025

Canterbury Christ Church University
2023-2024

Medical Research Council
2023

Ricardo (United Kingdom)
2023

Royal Botanic Gardens, Kew
2022

University of Oxford
2021

University of Exeter
2020

University of Connecticut
2018

University of Hartford
2018

<b>Objective</b> To evaluate the diagnosis of myocardial infarction using a high sensitivity troponin I assay and sex specific diagnostic thresholds in men women with suspected acute coronary syndrome. <b>Design</b> Prospective cohort study. <b>Setting</b> Regional cardiac centre, United Kingdom. <b>Participants</b> Consecutive patients syndrome (n=1126, 46% women). Two cardiologists independently adjudicated by (men 34 ng/L, 16 ng/L) compared current practice where contemporary (50 single...

10.1136/bmj.g7873 article EN cc-by BMJ 2015-01-21

Concern over the reliability of conventional poverty studies has focused attention on need to demonstrate that those identified as poor are actually experiencing hardship. This paper takes a step in this direction by examining using living standards approach derived from literature deprivation and social exclusion. Deprivation – defined an enforced lack socially perceived necessities emerged way identifying who is missing out what community regards (or essentials) life. Social exclusion...

10.1002/j.1839-4655.2008.tb00097.x article EN Australian Journal of Social Issues 2008-12-01

Significance Legumes, like peas, beans, and lentils, are high in protein because they form associations with specialized nitrogen-fixing bacteria. Plants provide the bacteria carbon receive nitrogen return, but some bacterial strains more than others. We show that pea plants supply resources to poor at fixing only if have no other choice. If a better strain is present, withheld. This indicates legumes can make conditional decisions, giving them remarkable control over their symbiotic...

10.1073/pnas.2025760118 article EN Proceedings of the National Academy of Sciences 2021-05-03

Transmissible vaccines are an emerging biotechnology that hold prospects to eliminate pathogens from wildlife populations. Such would genetically modify naturally occurring, nonpathogenic viruses (“viral vectors”) express pathogen antigens while retaining their capacity transmit. The epidemiology of candidate viral vectors within the target population has been notoriously challenging resolve but underpins selection effective prior major investments in vaccine development. Here, we used...

10.1073/pnas.2216667120 article EN cc-by Proceedings of the National Academy of Sciences 2023-03-06

Interrupting pathogen transmission between species is a priority strategy to mitigate zoonotic threats. However, avoiding counterproductive interventions requires knowing animal reservoirs of infection and the dynamics within them, neither which are easily ascertained from cross-sectional surveys that now dominate investigations into newly discovered viruses. We used biobanked sera metagenomic data reconstruct recently bat-associated influenza virus (BIV; H18N11) over 12 years in three zones...

10.1126/sciadv.ads1267 article EN cc-by-nc Science Advances 2025-02-05

1 Resprouting in woody plants is a trait that facilitates persistence disturbance-prone environments. Patterns of allocation resources for resprouting may depend on the severity disturbance to which are adapted. Fire-adapted allocate more below-ground structures after destruction above-ground structures. However, resprout response disturbances where survive remobilize resprouting. 2 In coastal sand dunes, stem leaning and partial uprooting trees result high frequency (38·9% individuals;...

10.1111/j.1365-2435.2008.01405.x article EN Functional Ecology 2008-04-22

The infectious life cycle of human papillomaviruses (HPVs) is tightly linked to keratinocyte differentiation. Evidence suggests a sophisticated interplay between host gene regulation and virus replication. Alternative splicing an essential process for viral expression, generally upregulated by serine arginine-rich factors (SRSFs). SRSF activity can be positively or negatively controlled cycles phosphorylation/dephosphorylation. Here we show that HPV16 infection leads accumulation the...

10.1099/jgv.0.001402 article EN cc-by Journal of General Virology 2020-03-17

Vaccination is a powerful tool in combating infectious diseases of humans and companion animals. In most wildlife, including reservoirs emerging human diseases, achieving sufficient vaccine coverage to mitigate disease burdens remains logistically unattainable. Virally vectored “transmissible” vaccines that deliberately spread among hosts are potentially transformative, but still theoretical, solution the challenge immunising inaccessible wildlife. Progress towards real-world application...

10.1371/journal.pbio.3001580 article EN cc-by PLoS Biology 2022-04-19

Questions: Is multi-stemming a survival strategy in response to chronic disturbance? under phylogenetic control? What environmental factors are associated with multi-stemming? When do trees initiate growth of multiple stems? Do multi-stemmed have limited stature? Location: Subtropical Indian Ocean coastal dune forest at Cape Vidal the Greater St. Lucia Wetland Park, northeastern South Africa. Methods: Tree physiognomy and conditions were sampled 20 transects that 300 m long 5 wide. Results:...

10.1658/1100-9233(2007)18[693:mtiscd]2.0.co;2 article EN Journal of Vegetation Science 2007-01-01

Abstract Questions: Is multi‐stemming a survival strategy in response to chronic disturbance? under phylogenetic control? What environmental factors are associated with multi‐stemming? When do trees initiate growth of multiple stems? Do multi‐stemmed have limited stature? Location: Subtropical Indian Ocean coastal dune forest at Cape Vidal the Greater St. Lucia Wetland Park, northeastern South Africa. Methods: Tree physiognomy and conditions were sampled 20 transects that 300 m long 5 wide....

10.1111/j.1654-1103.2007.tb02583.x article EN Journal of Vegetation Science 2007-02-24

Abstract Rabies is a viral zoonosis transmitted by vampire bats across Latin America. Substantial public health and agricultural burdens remain, despite decades of culls livestock vaccinations. Virally vectored vaccines that spread autonomously through bat populations are theoretically appealing solution to managing rabies in its reservoir host. We investigate the biological epidemiological suitability betaherpesvirus (DrBHV) act as vaccine vector. In 25 sites Peru with serological and/or...

10.1038/s41467-020-19832-4 article EN cc-by Nature Communications 2020-11-23

Sandplain heathlands are disturbance‐dependent plant communities that occur infrequently in coastal areas of the northeastern United States. We hypothesize salt spray plays a role maintaining composition heathland community by excluding salt‐intolerant species close to ocean. examined distributions Solidago nemoralis , Myrica pensylvanica Pinus rigida and Quercus spp. conducted greenhouse studies determine whether different levels tolerance explain patterns found field. common forb shrub...

10.3732/ajb.90.8.1188 article EN American Journal of Botany 2003-08-01
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