The pore size of porous scaffold plays a critical role in bone regeneration, but its mechanism and optimal value remain unclear. This study investigated the effect on hydromechanical properties correlation with cellular response regeneration. Porous titanium scaffolds similar porosity different sizes (400, 650, 850, 1100 μm) were fabricated by selective laser melting. Their derived computational fluid dynamics analysis. MC3T3 cells dynamic seeded cultured to evaluate response. rabbit distal...

// Xiang Zhou 1 , Dimple Natino 2 Zili Qin 3 Dong Wang Zhen Tian 4 Xuan Cai Bo 5 and Xijing He Department of Orthopaedics, Second Affiliated Hospital Xi'an Jiaotong University, Xi'an, China Biomedical Sciences, Florida State University College Medicine, Tallahassee, FL, USA Otolaryngology, Otorhinolaryngology Hospital, The First Sun Yat-sen Guangzhou, Infectious Diseases, Pharmacology, School Basic Medical Science, Health Science Center, Correspondence to: He, email: xijing_h@vip.tom.com...

Background: Echinococcus granulosus is a zoonotic parasitic disease caused by the larval stage of parasite Echinococcus, which has long incubation period, expensive diagnosis and treatment, duration medication, so it brings great economic burden to patients their families. Shangri‐La City one counties with high prevalence echinococcosis in Yunnan Province. The antigen‐positive rate feces there potential risk infecting people. Evaluation comprehensive prevention control intervention different...

BACKGROUND Echinococcosis is prevalent in 9 provinces Western and Northern China. An epidemiological survey of echinococcosis 2012 2016 showed cases Yunnan Province. AIM To understand the spatial distribution characteristics for prevention control to reduce risk infection METHODS Based on China Information System Disease Control Prevention (CISDCP), reported from 36 hospitals 34 Centers were investigated epidemiologically analyzed 2021 2022. The exclusion criteria included suspected cases,...

This paper reports a facile strategy of integrating composite synthesis and pore fabrication into one step to fabricate anisotropic porous chitosan/hydroxyapatite (CS/HA) scaffolds for the first time. These orientation-structured CS/HA exhibited highly structure, uniform optimal sizes (200∼500 μm), high porosity (ca. 85%), unidirectional interconnected network, excellent mechanical properties. The architecture was formed spontaneously accompanied by process in situprecipitation HA CS matrix,...

Abstract Thermal conductive polymer composite pipes have been used to replace metal that are easy be corroded. However, the low thermal conductivity of matrix is critical factor limiting their applications. Here, large‐size exfoliation graphene and carbon nanotube (CNT) proposed prepare thermal‐conductive polyethylene nanocomposites with a filler content. Expanded graphite CNT co‐dispersed by high pressure homogenizer in presence polyvinyl pyrrolidone. Such dispersion method can maintain...

This secondary analysis of a larger study compared adherence to telephone-administered cognitive-behavioral therapy (T-CBT) vs. face-to-face CBT and depression outcomes in depressed primary care patients with co-occurring problematic alcohol use. To our knowledge, T-CBT has never been directly such sample patients. Participants were randomized 1:1 ratio or for depression. receiving (n = 50) 53) at baseline, end treatment (week 18), three-month six-month follow-ups. Face-to-face groups did...

BACKGROUND Anterior cervical plate and cage fixation system (ACPC) used in anterior corpectomy fusion (ACCF) is reported to incur excess complications. This study aimed introduce integrated (IFC) into ACCF eliminate the (ACP)-related MATERIAL AND METHODS One validated intact 3 ACCF-simulated C3-C7 spine models were developed. In models, C5 was corpectomied fixed by IFC or ACPC. For each model, 1.0 Nm moments of flexion, extension, lateral bending, torsion imposed on C3 vertebra. The range...

This was an in vitro and vivo study to develop a novel artificial cervical vertebra intervertebral complex (ACVC) joint goat model provide new method for treating degenerative disc disease the spine. The objectives of this were test safety, validity, effectiveness ACVC by preclinical data clinical trial humans future. We designed based on radiological anatomical human spines, established animal implanting into spines prior implantation through anterior approach, evaluated clinical,...

An in vitro biomechanical study.To determine the initial stability and function of a novel total atlanto-odontoid joint arthroplasty system (TAAS) human cadaveric cervical spine models by comparing it with conventional method.Resection odontoid anterior arch atlas results atlantoaxial instability, which if left uncorrected may lead to severe neurological complications. Currently, such instability is corrected and/or posterior fusion. However, this considerable motion loss complex.Flexibility...

To study and measure the anatomic structure of lumbar vertebral endplate in healthy adults by computed tomography(CT) technique order to provide a useful guidance for optimal design clinical application prostheses.Sixty (male female equals) were recruited full-waist CT scan after signing informed consent form imaging department Second Affiliated Hospital Xi'an Jiaotong University. The scanning data was imported into computer aided software Mimics 16.0 3D reconstruction measurement....

The aim of the study was to examine whether there excessive endoplasmic reticulum stress (ERs) in islets high‑fat diet (HFD)‑induced obese mice, as well effects ERs on β‑cell function. Male C57BL/6J mice were fed a HFD for 16 weeks. Pancreatic function evaluated using intraperitoneal glucose tolerance and insulin release tests, via electron microscopy. expression activating transcription factor 6 (ATF6) phosphorylated (p)‑eukaryotic initiation 2α (eIF2α) detected immunofluorescence staining...

OBJECTIVE:To determine the range of motion and stability human cadaveric cervical spine after implantation a novel artificial disc vertebra system by comparing an intact group fusion group.METHODS: Biomechanical tests were conducted on 18 specimens.The index measured to study function compared with group.RESULTS: In all cases, maintained intervertebral reestablished vertebral height at operative level.After its implantation, there was no significant difference in (ROM) C 3-7 directions...

Objective: Hip osteoarthritis (HOA) is one of the most common types and affects nearly 10% men 18% women who are >60 years age worldwide. It has been demonstrated to be a genetic disease with 50% heritability risk. Recently, TLR-9 gene associated knee OA in both Turkish Chinese populations, but relationship between HOA not evaluated. In this study, we aimed evaluate variants predisposition Han individuals HOA. Methods: A total 730 patients 1220 healthy controls were recruited hospital-based...

Some studies have suggested that early surgical treatment can effectively improve the prognosis of cervical spinal cord injury without radiological abnormality, but no research has focused on development a prognostic model abnormality. This retrospective analysis included 43 patients with Seven potential factors were assessed: age, sex, external force strength causing damage, duration disease, degree stenosis, Japanese Orthopaedic Association score, and physiological curvature. A was...

This study investigates the molecular intricacies of transmembrane protein TSP11 gene in

Abstract Background Osteoporosis (OP) is a complex bone metabolism disorder characterized by the loss of minerals and an increased risk fracture. A recent study reported relationship macrophage erythroblast attacher gene ( MAEA ) with low mineral density in postmenopausal Japanese women. Our aimed to investigate association osteoporosis (PMOP) Han Chinese individuals. Methods total 968 unrelated women comprising 484 patients PMOP controls were recruited. Four tag single nucleotide...