A5016239479- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Animal Virus Infections Studies
- Bacteriophages and microbial interactions
- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Long-Term Effects of COVID-19
- Monoclonal and Polyclonal Antibodies Research
- Genomics and Phylogenetic Studies
- Burkholderia infections and melioidosis
Academy of Military Medical Sciences
2023-2024
Institute of Microbiology
2022-2023
VRprofile2 is an updated pipeline that rapidly identifies diverse mobile genetic elements in bacterial genome sequences. Compared with the previous version, three major improvements were made. First, user-friendly visualization could aid users investigating antibiotic resistance gene cassettes conjunction various multiple region mosaic structure. compare predicted to collected known similar architecture. A new mobilome indicator was proposed give overall estimation of size individual...
Abstract Acinetobacter baumannii has been listed as one of the most critical pathogens in nosocomial infections; however, key genes and mechanisms to adapt host microenvironment lack in-depth understanding. In this study, a total 76 isolates (from 8 12 per patient, spanning 128 188 days) were longitudinally collected from eight patients investigate within-host evolution A. baumannii. A 70 mutations identified, 80% which nonsynonymous, indicating important role positive selection. Several...
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants raises concerns regarding the effectiveness immunity acquired from previous breakthrough infections (BTIs) or reinfections (RIs) against current circulating subvariants. In this study, we prospectively investigate dynamic changes virus-specific antibody and T cell responses among 77 adolescents following BA.2.3 BTI with without subsequent BA.5 RI. Notably, neutralizing antibodies (NAbs) titers...
Abstract Background To determine an appropriate dose of, and immunization schedule for, a vaccine SCoK against COVID‐19 for efficacy study; herein, we conducted randomized controlled trials to assess the immunogenicity safety of this in adults. Methods These randomized, double‐blind, placebo‐controlled phase 1 2 were Binhai District, Yan City, Jiangsu Province, China. Younger older adult participants sequentially recruited into different groups be intramuscularly administered 20 or 40 μg...
A Novel Prophylaxis Strategy Using Ecotin as Promising Adjuvant for Fc-RBD Fusion Protein Vaccine of SARS-CoV-2Yakun Sun#, Rui Zheng#, Deyu Li#,Yitai Fang#, Liangyan Zhang, Xiaolan Yang, Wenjing Yu, Yeqing Tu, Dan Lu, Deyan Luo*, Hui Wang*Department Infection Immunity&Defense, State Key Laboratory Pathogen and Biosecurity, Beijing Institute Microbiology Epidemiology, Beijing, ChinaCorrespondence to:Dr. Wangwanghui_dyx@hotmail.com20 Dongda Street, Fengtai District, 100071, ChinaTel: +86 10...