Li‐Qun Fang

ORCID: 0000-0002-4981-1483
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About
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Research Areas
  • Viral Infections and Vectors
  • COVID-19 epidemiological studies
  • Mosquito-borne diseases and control
  • Animal Disease Management and Epidemiology
  • Influenza Virus Research Studies
  • Viral Infections and Outbreaks Research
  • Vector-borne infectious diseases
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Fire effects on ecosystems
  • Viral gastroenteritis research and epidemiology
  • Respiratory viral infections research
  • Vector-Borne Animal Diseases
  • Zoonotic diseases and public health
  • Data-Driven Disease Surveillance
  • Climate Change and Health Impacts
  • Pneumonia and Respiratory Infections
  • Long-Term Effects of COVID-19
  • Yersinia bacterium, plague, ectoparasites research
  • Energy and Environment Impacts
  • Virology and Viral Diseases
  • Travel-related health issues
  • Viral Infections and Immunology Research
  • Species Distribution and Climate Change
  • Malaria Research and Control

Anhui Medical University
2019-2025

Academy of Military Medical Sciences
2011-2025

Guiyang Medical University
2022-2025

Institute of Microbiology
2015-2024

Institute of Microbiology
2019-2024

Czech Academy of Sciences, Institute of Microbiology
2009-2024

Fudan University
2022

West China Hospital of Sichuan University
2022

Harbin Medical University
2015-2022

Sichuan University
2022

Our manuscript was based on surveillance cases of COVID-19 identified before January 26, 2020. As February 20, 2020, the total number confirmed in mainland China has reached 18 times our manuscript. While methods and main conclusions original analyses remain solid, we decided to withdraw this preprint for time being, will replace it with a more up-to-date version shortly. Should you have any comments or suggestions, please feel free contact corresponding author.

10.1101/2020.02.10.20021675 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-02-11

Nationwide prospective surveillance of all-age patients with acute respiratory infections was conducted in China between 2009‒2019. Here we report the etiological and epidemiological features 231,107 eligible enrolled this analysis. Children <5 years old school-age children have highest viral positivity rate (46.9%) bacterial (30.9%). Influenza virus, syncytial virus human rhinovirus are three leading pathogens proportions 28.5%, 16.8% 16.7%, Streptococcus pneumoniae, Mycoplasma pneumoniae...

10.1038/s41467-021-25120-6 article EN cc-by Nature Communications 2021-08-18

Abstract Understanding ecological niches of major tick species and prevalent tick-borne pathogens is crucial for efficient surveillance control diseases. Here we provide an up-to-date review on the spatial distributions ticks in China. We map at county level 124 species, 103 agents, human cases infected with 29 (subspecies) that were reported China during 1950−2018. Haemaphysalis longicornis found to harbor highest variety followed by Ixodes persulcatus , Dermacentor nutalli Rhipicephalus...

10.1038/s41467-021-21375-1 article EN cc-by Nature Communications 2021-02-17

Abstract National-based prospective surveillance of all-age patients with acute diarrhea was conducted in China between 2009‒2018. Here we report the etiological, epidemiological, and clinical features 152,792 eligible enrolled this analysis. Rotavirus A norovirus are two leading viral pathogens detected patients, followed by adenovirus astrovirus. Diarrheagenic Escherichia coli nontyphoidal Salmonella bacterial pathogens, Shigella Vibrio parahaemolyticus . Patients aged &lt;5 years had...

10.1038/s41467-021-22551-z article EN cc-by Nature Communications 2021-04-29

In early March 2022, a major outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant spread rapidly throughout Shanghai, China. Here we aimed to provide description epidemiological characteristics and spatiotemporal transmission dynamics under population-based screening lockdown policies implemented in Shanghai.

10.1016/j.lanwpc.2022.100592 article EN cc-by-nc-nd The Lancet Regional Health - Western Pacific 2022-09-07

Human brucellosis incidence in China has been increasing dramatically since 1999. However, epidemiological features and potential factors underlying the re-emergence of disease remain less understood.Data on human animal cases at county scale were collected for year 2004 to 2010. Also environmental socioeconomic variables. Epidemiological including spatial temporal patterns characterized, related heterogeneity trend analysed using Poisson regression analysis, Granger causality autoregressive...

10.1186/1471-2334-13-547 article EN cc-by BMC Infectious Diseases 2013-11-16

Air pollution in Beijing, especially PM2.5, has received increasing attention the past years. Despite Beijing being one of most polluted cities world, there still been a lack quantitative research regarding health impact PM2.5 on diseases Beijing. In this study, we aimed to characterize temporal pattern and its potential association with human influenza Based data collected hourly ambient from year 2008 2013 monthly cases 2011, investigated patterns over five-year period utilized wavelet...

10.1186/1476-069x-13-102 article EN cc-by Environmental Health 2014-12-01

Abstract First discovered in rural areas of middle-eastern China 2009, severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne zoonosis affecting hundreds cases reported each year. Using the national surveillance data from 2010 to 2013, we conducted this retrospective epidemiological study and risk assessment SFTS China. We found that incidence its epidemic are continuing grow, but case fatality rate (CFR) has steadily decreased. most commonly affected elderly farmers...

10.1038/srep09679 article EN cc-by Scientific Reports 2015-04-23

Nationwide nonpharmaceutical interventions (NPIs) have been effective at mitigating the spread of novel coronavirus disease (COVID-19), but their broad impact on other diseases remains under-investigated. Here we report an ecological analysis comparing incidence 31 major notifiable infectious in China 2020 to average level during 2014-2019, controlling for temporal phases defined by NPI intensity levels. Respiratory and gastrointestinal or enteroviral declined more than sexually transmitted...

10.1038/s41467-021-27292-7 article EN cc-by Nature Communications 2021-11-26

Abstract Background As of April 2, 2020, the global reported number COVID-19 cases has crossed over 1 million with more than 55,000 deaths. The household transmissibility SARS-CoV-2, causative pathogen, remains elusive. Methods Based on a comprehensive contact-tracing dataset from Guangzhou, we estimated both population-level effective reproductive and individual-level secondary attack rate (SAR) in setting. We assessed age effects infectivity during their incubation period. Results A total...

10.1101/2020.04.11.20056010 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-04-15

Abstract Background The growing epidemics of severe fever with thrombocytopenia syndrome (SFTS), an emerging tick-borne disease in East Asia, and its high case fatality rate have raised serious public health concerns. Methods Surveillance data on laboratory-confirmed SFTS cases China were collected. spatiotemporal dynamics epidemiological features explored. socioeconomic environmental drivers identified for diffusion using survival analysis persistence a two-stage generalized boosted...

10.1093/cid/ciaa1561 article EN cc-by-nc-nd Clinical Infectious Diseases 2020-10-15

A four-year-old boy developed recurrent fever and severe pneumonia in April, 2022. High-throughput sequencing revealed a reassortant avian influenza A-H3N8 virus (A/Henan/ZMD-22-2/2022(H3N8) with avian-origin HA NA genes. The six internal genes were acquired from Eurasian lineage H9N2 viruses. Molecular substitutions analysis the haemagglutin retained avian-like receptor binding specificity but that PB2 possessed sequence changes (E627K) associated increased virulence transmissibility...

10.1038/s41467-022-34601-1 article EN cc-by Nature Communications 2022-11-10

Dear editor, Currently, the omicron XBB subvariant, which is a recombinant of BJ.1 and BA.2.75, was first identified in India August 2022 now its new sublineage XBB.1.5, has been reported from at least 79 countries become predominant world,1WHOWeekly epidemiological update on COVID-19-8 March 2023.https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---8-march-2023Date accessed: 15, 2023Google Scholar raising concern neutralizing activity elicited by breakthrough...

10.1016/j.lanwpc.2023.100759 article EN cc-by-nc-nd The Lancet Regional Health - Western Pacific 2023-04-01

Abstract Hemorrhagic fever with renal syndrome (HFRS) is an important public health problem in the People’s Republic of China, accounting for 90% human cases reported globally. In this study, a landscape epidemiologic approach, combined geographic information system and remote sensing techniques, was applied to increase our understanding HFRS due Hantaan virus its relationship elements China. The considered were elevation, normalized difference vegetation index (NDVI), precipitation, annual...

10.3201/eid1309.061481 article EN cc-by Emerging infectious diseases 2007-09-01

Hemorrhagic fever with renal syndrome (HFRS) is endemic in many provinces high incidence mainland China, although integrated intervention measures including rodent control, environment management and vaccination have been implemented for over ten years. In this study, we conducted a geographic information system (GIS)-based spatial analysis on distribution of HFRS cases the whole country an objective to inform priority areas public health planning resource allocation.Annualized average at...

10.1186/1471-2334-6-77 article EN cc-by BMC Infectious Diseases 2006-04-26

The transmission of hemorrhagic fever with renal syndrome (HFRS) is influenced by climatic variables. However, few studies have examined the quantitative relationship between climate variation and HFRS transmission.We potential impact variability on developed climate-based forecasting models for in northeastern China.We obtained data monthly counts reported cases Elunchun Molidawahaner counties 1997-2007 from Inner Mongolia Center Disease Control Prevention Chinese Bureau Meteorology....

10.1289/ehp.0901504 article EN public-domain Environmental Health Perspectives 2010-02-08

The outbreak of human infections with an emerging avian influenza A (H7N9) virus occurred in China early 2013. It remains unknown what and how the underlying risk factors were involved bird-to-human cross-species transmission. To illustrate dynamics viral spread, we created a thematic map displaying distribution affected counties plotted epidemic curves for three most provinces whole country. We then collected data agro-ecological, environmental meteorological at county level used boosted...

10.1038/srep02722 article EN cc-by-nc-sa Scientific Reports 2013-09-26

Background Since late 2003, the highly pathogenic influenza A H5N1 had initiated several outbreak waves that swept across Eurasia and Africa continents. Getting prepared for reassortment or mutation of viruses has become a global priority. Although spreading mechanism been studied from different perspectives, its main transmission agents spread route problems remain unsolved. Methodology/Principal Findings Based on compilation time location outbreaks November 2003 to December 2006, we report...

10.1371/journal.pone.0013575 article EN cc-by PLoS ONE 2010-10-22
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