A5000561844- Acute Ischemic Stroke Management
- Alzheimer's disease research and treatments
- Cerebrovascular and Carotid Artery Diseases
- Neurological Disease Mechanisms and Treatments
- Pancreatic function and diabetes
- Liver Disease Diagnosis and Treatment
- Thyroid Cancer Diagnosis and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Metabolism, Diabetes, and Cancer
- Viral Infections and Vectors
- Tuberculosis Research and Epidemiology
- Intracerebral and Subarachnoid Hemorrhage Research
- Hepatitis B Virus Studies
- Radiomics and Machine Learning in Medical Imaging
- Cancer Research and Treatments
- Cholinesterase and Neurodegenerative Diseases
- Fermentation and Sensory Analysis
- Cell death mechanisms and regulation
- Inflammasome and immune disorders
- Esophageal Cancer Research and Treatment
- RNA modifications and cancer
- Mitochondrial Function and Pathology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mesenchymal stem cell research
- Viral Infections and Outbreaks Research
Tianjin Huanhu Hospital
2016-2025
Shenzhen Institutes of Advanced Technology
2021-2025
Qingdao University
2008-2025
Hunan Normal University
2024-2025
Affiliated Hospital of Qingdao University
2021-2025
Macau University of Science and Technology
2025
First Affiliated Hospital of Xi'an Jiaotong University
2022-2024
Shanghai Jiao Tong University
2014-2024
Beijing Language and Culture University
2023-2024
Second Hospital of Tianjin Medical University
2023-2024
PANoptosis is a newly identified type of regulated cell death that consists pyroptosis, apoptosis, and necroptosis, which simultaneously occur during the pathophysiological process infectious inflammatory diseases. Although our previous literature mining study suggested might in neuronal ischemia/reperfusion injury, little experimental research has been reported on existence PANoptosis. In this study, we used vivo vitro retinal models injury to investigate whether PANoptosis-like...
Type 1 diabetes mellitus (T1DM) is an autoimmune disorder resulted from T cell-mediated destruction of pancreatic β-cells, how to regenerate β-cells and prevent the remnant neogenetic a tough problem. Immunomodulatory propertity mesenchymal stem cell make it illuminated overcome it. We assessed long-term effects implantation Wharton's jelly-derived cells (WJ-MSCs) umbilical cord for Newly-onset T1DM. Twenty-nine patients with newly onset T1DM were randomly divided into two groups, in group I...
Some scholars have recently developed the concept of PANoptosis in study infectious diseases where pyroptosis, apoptosis and necroptosis act consort a multimeric protein complex, PANoptosome. This allows all components to be regulated simultaneously. provides new way regulation cell death, that different types death may at same time. To test whether exists other than diseases, we chose cerebral ischemia/reperfusion injury as research model, collected articles researching from three major...
Background: Considering the pivotal role of inflammasome/pyroptosis in biological function, we visually analyzed research hotspots related to brain this work through method bibliometrics from Web Science (WOS) Core database over past two decades. Methods: Documents were retrieved WOS Collection on October 16, 2020. The search terms and strategies used for are as follow: # 1, “pyroptosis”; 2, “pyroptotic”; 3, “inflammasome”; 4, “pyroptosome”; 5 “brain”; 6, “# 1” OR 2” 3” 4”; 7, 5” AND 6”. We...
Abstract Hemorrhagic fever with renal syndrome (HFRS) is an important public health problem in the People’s Republic of China, accounting for 90% human cases reported globally. In this study, a landscape epidemiologic approach, combined geographic information system and remote sensing techniques, was applied to increase our understanding HFRS due Hantaan virus its relationship elements China. The considered were elevation, normalized difference vegetation index (NDVI), precipitation, annual...
Hemorrhagic fever with renal syndrome (HFRS) is endemic in many provinces high incidence mainland China, although integrated intervention measures including rodent control, environment management and vaccination have been implemented for over ten years. In this study, we conducted a geographic information system (GIS)-based spatial analysis on distribution of HFRS cases the whole country an objective to inform priority areas public health planning resource allocation.Annualized average at...
We investigated secular trends in the age of stroke onset and incidence a low-income population rural China.The study was recruited from population-based surveillance conducted township Tianjin, China, 1992 to 2014. The mean first-ever were assessed by sex subtype. Risk factor surveys same both 1991 2011.A total 1053 patients experienced men significantly decreased 0.28 years annually overall, 0.56 for intracerebral hemorrhage, 0.22 ischemic (P<0.05). However, similar trend not observed...
Guided by the social embeddedness model of thriving at work, this paper explores how nursing organizational culture, work engagement and affective commitment affect nurses' work.Thriving has implications for better employee organization outcomes. The antecedents among population needs to be expanded analysing cross-level impact individual characteristics.A cross-sectional design was used collect data from 1437 frontline nurses in a tertiary teaching hospital China between April May 2020...
Although the age-specific incidence and mortality of stroke is higher among men, has a greater clinical effect on women. However, sex differences in elderly patients are unknown. Therefore, we aimed to assess patients.Between 2005 2013, recruited 1484 consecutive acute ischemic (AIS) (≥75 years old) from specialized neurology hospital Tianjin, China. Information regarding their subtypes, severity, risk factors, outcomes at 3 12 months after were recorded.Comparing with women had...
Total cholesterol is a well-documented risk factor for coronary disease. Previous studies have shown that high total level associated with better stroke outcomes, but the association of low levels and ischemic outcomes rare. Therefore, we aimed to assess among acute patients in China. This study recruited 6407 atherothrombotic infarction from Tianjin, China, between May 2005 September 2014. All were categorized into five groups according TC quintiles at admission. Differences subtypes,...
Abstract Background Diosmetin is a bioflavonoid compound naturally abundant in citrus fruits. It found to perform variety of activities, while its antitumor property osteosarcoma, malignant tumor with unmet clinical treatment, remained unknown. Methods Colony formation assay, cell cycle analysis and apoptosis were conducted respectively observe the effect diosmetin on proliferation human osteosarcoma cells. Western blot immunoprecipitation used detect expression apoptotic molecules...
Abstract Context Papillary thyroid carcinoma (PTC) is the most common malignant cancer. Several clinicopathological features may affect therapeutic efficacy. Objective To analyze relationship between thyroglobulin antibodies (TgAb) with and efficacy of 131I ablation in PTC patients. Methods A total 548 patients who underwent thyroidectomy subsequent were enrolled. The TgAb-positive TgAb-negative groups compared. characteristics risk factors affecting analyzed. Results 157 cases (28.65%)...
This study examines the impact of a COVID-19 pandemic-derived online medical service on cardiovascular patient visits and assesses whether these services can ease strain resources. investigated pandemic cardiology hospital operations. We analyzed key primary indicators in cardiology, including outpatient visits, inpatient improvement rates, cure mortality over three years from 2019 to 2021. Furthermore, assessed influence development Internet-based treatment disease. Specifically, we...
This study demonstrates a strong association of high urinary iodine with thyroid nodules and papillary cancer as well aggressive features, suggesting that is risk factor for cancer. The intake has been suggested but not established. objective the was to evaluate relationship between urine levels nodule We preoperatively tested fasting in 154 patients correlated results pathological diagnoses compared 306 subjects normal control. median (MUI) 331.33 μg/L benign versus 466.23 (PTC) (P=0.003),...