Isaac Kimera

ORCID: 0000-0003-4024-1872
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About
Contact & Profiles
Research Areas
  • HIV-related health complications and treatments
  • HIV/AIDS Research and Interventions
  • Malaria Research and Control
  • Medication Adherence and Compliance
  • Mosquito-borne diseases and control
  • Blood Pressure and Hypertension Studies
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Child Nutrition and Water Access
  • Travel-related health issues
  • COVID-19 epidemiological studies
  • Cervical Cancer and HPV Research
  • HIV, Drug Use, Sexual Risk
  • Interprofessional Education and Collaboration
  • Child and Adolescent Health
  • Global Cancer Incidence and Screening
  • HIV Research and Treatment
  • COVID-19 Clinical Research Studies
  • Global Public Health Policies and Epidemiology
  • Insect Pest Control Strategies
  • HIV/AIDS Impact and Responses
  • Breastfeeding Practices and Influences
  • HIV/AIDS drug development and treatment
  • COVID-19 and healthcare impacts
  • Lipoproteins and Cardiovascular Health
  • Global Maternal and Child Health

Makerere University
2020-2024

Infectious Diseases Institute
2023

Case Western Reserve University
2023

Ministry of Health
2023

Torbay and South Devon NHS Foundation Trust
2023

British Heart Foundation
2023

Barking, Havering And Redbridge University Hospitals NHS Trust
2023

The Royal Free Hospital
2023

University College London
2023

Malaria Consortium
2022

Malaria control in Africa relies heavily on indoor vector management, primarily residual spraying and insecticide treated bed nets. Little is known about outdoor biting behaviour or even the dynamics of infection risk sleeping household occupants. In this paper we explore preferred sites human body some ramifications regarding exposure management. We undertook whole-night landing catches Anopheles arabiensis South gambiae s.s. funestus Uganda, for seated persons wearing short sleeve shirts,...

10.1186/s13071-015-0677-9 article EN cc-by Parasites & Vectors 2015-01-01

Research Letter Introduction: Measures to limit the spread of COVID-19, such as movement restrictions, are anticipated worsen outcomes for chronic conditions hypertension (HTN), in part due decreased access medicines. However, actual impact lockdowns on medicines and HTN control has not been reported. Between March 25 June 30, 2020, Government Uganda instituted a nationwide lockdown. Health facilities remained open, however motor vehicle transportation was largely banned. In Ugandan public...

10.5334/gh.928 article EN cc-by Global Heart 2021-01-01

Abstract Multi-month dispensing (MMD) is a patient-centered approach in which stable patients receive medicine refills of three months or more. In this pre-post longitudinal study, we determined hypertension and HIV treatment outcomes cohort hypertensive PLHIV at baseline 12 receiving integrated MMD. At each clinical encounter, one healthcare provider attended to both needs patient an clinic. Among the 1,082 who received MMD, mean age was 51 (SD = 9) years 677 (63%) were female. start...

10.1038/s41371-022-00655-3 article EN cc-by Journal of Human Hypertension 2022-03-04

To adapt a World Health Organization HEARTS-based implementation strategy for hypertension (HTN) control at large urban HIV clinic in Uganda and determine six-month HTN outcomes among cohort of adult persons living with (PLHIV).Our included six elements: health education, medication adherence, lifestyle counseling; routine screening; task shifting treatment; evidence-based treatment protocol; consistent supply medicines free to patients; inclusion HTN-specific monitoring evaluation tools. We...

10.1186/s12913-022-08045-8 article EN cc-by BMC Health Services Research 2022-05-25

Persons living with HIV (PLHIV) receiving antiretroviral therapy (ART) have a high prevalence of hypertension (HTN) and increased risk mortality from cardiovascular diseases. HTN care integration is recommended in Uganda, though its implementation has lagged. In this study, we sought to analyze the cascades explore barriers facilitators HTN/HIV within large clinic urban Uganda.We conducted an explanatory sequential mixed methods study at Mulago ISS Kampala, Uganda. We determined proportions...

10.1186/s43058-021-00223-9 article EN cc-by Implementation Science Communications 2021-10-20

Cervical cancer is a serious health concern in Uganda. Early screening and detection certainly improves chances of survival treatment outcome. Sound knowledge positive attitudes highly influence acceptability uptake methods. This descriptive cross-sectional study determines towards Cancer amongst female out-patients aged 15 - 49 years, attending Health Centre IIIs Oyam District, Northern A systematically obtained sample 445 respondents was interviewed using semi-structured questionnaires...

10.4236/ojpm.2017.74005 article EN Open Journal of Preventive Medicine 2017-01-01

In this cohort study, we determined time to blood pressure (BP) control and its predictors among hypertensive PLHIV enrolled in integrated hypertension-HIV care based on the World Health Organization (WHO) HEARTS strategy at Mulago Immunosuppression Clinic Uganda. From August 2019 March 2020, aged

10.1038/s41371-024-00897-3 article EN cc-by Journal of Human Hypertension 2024-02-01

Malaria remains the number one cause of morbidity and mortality in Uganda. In 2009, United States President's Initiative (PMI) funded an indoor residual spraying (IRS) project 10 mid-northern districts, resulting marked reductions malaria prevalence over 5 years, from 62.5 percent to 7.2 percent. When ended IRS withdrawn, increased exponentially pre-IRS level 63 2016 was characterized by frequent life-threatening upsurges that were exacerbated a weak national led surveillance system with...

10.1186/s12936-022-04066-0 article EN cc-by Malaria Journal 2022-02-19

Background In Uganda, it is recommended that persons with HIV receive integrated care to address both hypertension and diabetes. However, the extent which appropriate diabetes delivered remains unknown was aim of this study. Methods We conducted a retrospective study among participants receiving for at least 1 year large urban clinic in Mulago, Uganda determine cascade. Results Of 1115 participants, majority were female ( n = 697, 62.5%) median age 50 years (Inter Quartile Range: 43, 56)....

10.1177/09564624231179497 article EN International Journal of STD & AIDS 2023-06-03

Abstract Globally, people living with HIV on antiretroviral therapy have an increased risk of cardiovascular disease. Hypertension is the most important preventable factor for disease and associated morbidity. We conducted exploratory survey hypertensive persons who received integrated hypertension care in a large clinic Uganda between August 2019 March 2020 to determine factors blood pressure control at six months. Controlled was defined as <140/90 mmHg. Multivariable logistic regression...

10.1038/s41371-022-00786-7 article EN cc-by Journal of Human Hypertension 2022-12-07

Abstract Background Malaria remains the number one cause of morbidity and mortality in Uganda. In 2009, United States’ President’s Initiative (PMI) funded an indoor residual spraying (IRS) project 10 Mid- northern districts, resulting marked reductions malaria prevalence over five years, from 62.5 percent to 7.2 percent. When was completed IRS subsequently withdrawn, increased dramatically pre-IRS level 63 2016 characterised by frequent life-threatening upsurges that were exasperated a weak...

10.21203/rs.3.rs-52816/v2 preprint EN cc-by-nc-sa Research Square (Research Square) 2021-07-28

BackgroundThe Makerere University Education for Interprofessional HIV Service Delivery in Uganda capacity-building programme provides online, in-service interprofessional education to health-care providers through a case-based approach. We used this training address suboptimal performance among providers.MethodsWe multilayered integrated and impact assessment on health outcomes. In partnership with Ugandan organisation implementing the US President's Emergency Plan AIDS Relief, we identified...

10.1016/s2214-109x(22)00153-x article EN cc-by-nc-nd The Lancet Global Health 2022-03-01

Abstract Background: Persons Living with HIV (PLHIV) receiving antiretroviral therapy (ART) have a high prevalence of hypertension (HTN) and increased risk mortality from cardiovascular diseases. HTN care integration is recommended in Uganda, though its implementation has lagged. In this study, we sought to analyze the cascades explore barriers facilitators HTN/HIV within large clinic urban Uganda. Methods: We conducted an explanatory sequential mixed methods study at Mulago ISS Kampala,...

10.21203/rs.3.rs-47726/v1 preprint EN cc-by Research Square (Research Square) 2020-07-23

Abstract In this cohort study, we determined time to blood pressure (BP) control and its predictors among hypertensive PLHIV enrolled in integrated hypertension-HIV care based on the World Health Organization (WHO) HEARTS strategy at Mulago Immunosuppression Clinic Uganda. From August 2019 March 2020, aged \(\ge\)18 years initiated Amlodipine 5mg mono-therapy for BP (140–159)/(90–99) mmHg or 5mg/Valsartan 80mg duo-therapy ≥ 160/90mmHg. Patients were followed with a treatment escalation plan...

10.21203/rs.3.rs-2641141/v1 preprint EN cc-by Research Square (Research Square) 2023-03-15

Abstract Background Malaria remains the number one cause of morbidity and mortality in Uganda. In 2009, an indoor residual spraying (IRS) programme was implemented 10 Northern districts, resulting marked reductions malaria burden, a prevalence just 7 percent. IRS withdrawn after five years among children subsequently increased dramatically from 2014-2016. This upsurge led to focus on training district staff surveillance, epidemic preparedness, response. An increase cases detected again 2018...

10.21203/rs.3.rs-52816/v1 preprint EN cc-by Research Square (Research Square) 2020-08-07

Abstract Background: Persons Living with HIV (PLHIV) receiving antiretroviral therapy (ART) have a high prevalence of hypertension (HTN) and increased risk mortality from cardiovascular diseases. HTN care integration is recommended in Uganda, though its implementation has lagged. In this study, we sought to analyze the cascades explore barriers facilitators HTN/HIV within large clinic urban Uganda. Methods: We conducted an explanatory sequential mixed methods study at Mulago ISS Kampala,...

10.21203/rs.3.rs-49530/v1 preprint EN cc-by Research Square (Research Square) 2020-07-30
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