- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Analytical Chemistry and Chromatography
- Paraquat toxicity studies and treatments
- Nanoparticles: synthesis and applications
- Bee Products Chemical Analysis
- Moringa oleifera research and applications
- Edible Oils Quality and Analysis
- Phytochemicals and Antioxidant Activities
- Ethnobotanical and Medicinal Plants Studies
- Electrospun Nanofibers in Biomedical Applications
- Natural Antidiabetic Agents Studies
- Cynara cardunculus studies
- Wound Healing and Treatments
- Research on Leishmaniasis Studies
- Analytical chemistry methods development
- Oral microbiology and periodontitis research
- Sesame and Sesamin Research
- Advanced Chemical Sensor Technologies
- Protein Interaction Studies and Fluorescence Analysis
- Medicinal Plant Research
- Parasitic infections in humans and animals
- Garlic and Onion Studies
- Tannin, Tannase and Anticancer Activities
- Nanocomposite Films for Food Packaging
Lorestan University of Medical Sciences
2016-2025
Baqiyatallah University of Medical Sciences
2024
Kurdistan University of Medical Sciences
2016-2019
Islamic Azad University, Khorramabad Branch
2011-2017
Bam University of Medical Sciences
2017
Islamic Azad University, Science and Research Branch
2014-2015
Islamic Azad University, Tehran
2012-2014
A green synthetic approach by using oak fruit hull (Jaft) extract for preparation of silver nanoparticles (AgNPs) was developed and optimized. Parameters affecting the synthesis AgNPs, such as temperature, pH, concentration (ratio plant sample to extraction solvent), were investigated Optimum conditions are follows: Ag + concentration, 1 mM; 40 g/L (4% w/v); pH = 9 45°C. Biosynthesized characterized UV-visible absorption spectroscopy (UV-Vis), Fourier-transform infrared (FT-IR), X-ray...
As a potent herbicide capable of contaminating water and soil environments, paraquat, which is still widely used worldwide, toxic to mammals, algae, aquatic animals, etc. Paraquat was loaded on novel nanoparticles composed pectin, chitosan, sodium tripolyphosphate (PEC/CS/TPP). The size, polydispersity index, ζ potential were characterized. Further assessments carried out by SEM, AFM, FT-IR, DSC. encapsulation highly efficient, there delayed release pattern paraquat. encapsulated less...
The present study was designed to evaluate antioxidant effects of betaine in the brain following administration levodopa and benserazide, which are routinely used treatment Parkinson's disease. Sprague-Dawley male rats were divided into (LD), Betaine (Bet.), plus (LD/Bet.), benserazide (LD/Ben.), betaine-benserazide (LD/Bet.-Ben.) control groups. experimental groups received LD 300 mg/kg, Bet. 1.5 % w/w total diet, Ben. 75 mg/kg distilled water controls for 10 consecutive days, orally....
To determine the chemical composition, antioxidant activity and antibacterial properties of essential oils aerial parts Salvia sclareoides (S. sclareoides).The oil areal S. was obtained by using hydrodistillation method composition volatile components analyzed gas chromatography coupled with mass spectrometry detector. The antimicrobial capacity investigated microdilution technique. activities were determined employing inhibition 2,2-diphenyl-1-picrylhydrazyl hydrate radical method.Mass...
A green synthetic approach using olive leaf extract was optimized for preparing silver nanoparticles (AgNPs). Parameters affecting the formation of such as temperature, exposure time to extract, pH, concentration nitrate, and (ratio plant sample extraction solvent) were investigated optimized. Optimum conditions synthesis are follows: Ag+ 1 mM, concentration, 8 % w/v; pH = 7, time, 4 h 45 °C. Synthesized characterized UV–Visible absorption spectroscopy, Fourier-transform infrared X-ray...
Cinnamomum zeylanicum (cinnamon) is a plant with potent antioxidant activity and has been used in traditional medicine for improvement of heart function. The effects cinnamon bark ethanolic extract were investigated against ischemia-induced arrhythmias injury an vivo rat model regional ischemia. was also standardized, its evaluated. Adult male Sprague-Dawley rats subjected to 30 min ischemia by occlusion the left anterior descending coronary artery followed 5 days reperfusion. Thirty-two...
Previous studies have reported that quercetin (Q) has a potential antibacterial and anticancer activity. However, its application is limited by many important factors including high hydrophobicity low absorption.In the current study, we synthesized characterized (Patent) novel chitosan-based nanohydrogel (ChiNH/Q). Encapsulation efficiency was confirmed UV/VIS spectrophotometer. Physicochemical characterization of ChiNH/Q assessed PDI, DLS, SEM, FTIR, XRD. The toxicity against five strains...
Diabetes mellitus is associated with the development of neuronal tissue damage in different central and peripheral nervous system regions. A common complication diabetes painful diabetic neuropathy. We have explored antihyperalgesic neuroprotective properties Rosmarinus officinalis L. extract (RE) a rat model streptozotocin (STZ)-induced diabetes. The nociceptive threshold motor coordination these rats was assessed using tail-flick rotarod treadmill tests, respectively. Activated caspase-3...
This study aims to evaluate the in vitro and vivo antileishmanial activities of Pistacia vera essential oil compare their efficacy with a reference drug, meglumine antimoniate (Glucantime®). (0-100 µg/mL) was evaluated against intracellular amastigote forms Leishmania tropica (MHOM/IR/2002/Mash2) then tested on cutaneous leishmaniasis male BALB/c mice by major (MRHO/IR/75/ER). In assay, it could be observed that P. significantly (p < 0.05) inhibited growth rate (IC50 21.3 ± 2.1...
Aim: This study was designed to evaluate the synergistic activities of hydroalcoholic extracts medicinal plants Origanum vulgare and Hypericum perforatum their active components, carvacrol hypericin against Staphylococcus aureus. Methods: The effects plants, as well hypericin, were examined using a checkered method S. aureus (ATCC 12600). Results: A fractional inhibitory concentration 0.5 obtained for combination O. H. 0.49 ingredients both which indicated effect. Conclusion: preliminary...
Background: Myrtus communis (M. communis) is a wild aromatic plant used for traditional herbal medicine that can be demonstrated in insecticidal, antioxidant, anti-inflammatory, and antimicrobial activity of its essential oils (MCEO). Aim: The present study aimed to evaluate the prophylactic effects M. oil (MCEO) against chronic toxoplasmosis induced by Tehran strain Toxoplasma gondii mice. Methods: Gas chromatography/mass spectrometry (GC/MS) analysis was performed determine chemical...
Background: Given the significant role of chitosan nanoparticles in medicine, present study aimed to assess vivo efficacy synthesized coated with thymol (CNCT) combating Toxoplasma gondii infection. Methods: Mice were administered CNCT orally at dosages ranging from 0.25 0.75 mg/kg/day for a duration 14 days. Following this treatment, they infected T. tachyzoites Rh strain induce acute toxoplasmosis. Then, mortality rate, parasite load, antioxidant activity, and gene expression level...
Abstract While 2D polymers with aromatic backbones have been increasingly receiving interest from various scientific disciplines, their nonaromatic counterparts are less investigated. In this work, poly( β ‐cyclodextrin)s (2D‐CDs) few hundred nanometers to millimeters lateral sizes and 0.7 nm thickness synthesized using graphene boron nitride as colloidal templates used for multivalent host‐guest interactions biological systems. Deposition of cyclodextrins on followed by crosslinking...
Dispersive liquid–liquid microextraction (DLLME) coupled with high-performance liquid chromatography (HPLC) equipped UV detector was used for the extraction and determination of efavirenz in plasma sample. Acetonitrile chloroform were as disperser solvents, respectively. Several parameters, including solvent, type dispersion volume pH, ionic strength media, well centrifuging time optimized. Samples injected on a reversed-phase C18 analytical column. The mobile phase consisted 20 mM phosphate...
Abstract Matrix solid-phase dispersion (MSPD) methodology as a quick and easy extraction method has been developed to extract oleuropein from Olea europaea leaves. This compared with conventional maceration Soxhlet (SOXE) methods. Variables affecting MSPD, such the sorbent material, ratio of sample elution solvent, volume have fully evaluated optimized. Oleuropein was successfully extracted by silica 350 μL dichloromethane–methanol (70 + 30, v/v) solvent. The calibration curve showed good...
Satureja khuzistanica jamzad (SKJ), which is a member of Lamiaceae, has various proven effects such as antispasmodic and anti-inflammatory, anti-diabetic, antioxidant, antifungal properties. However, the use essential oil plants limited due to their inherent instability in environment. Encapsulation with nanoparticles nanogel forms one stabilization methods. The aim this study was synthesize nano-gel based on chitosan (CS) extracts SKJ oil, evaluate antibacterial anticancer activities....