Julien Engelhardt

ORCID: 0000-0003-4024-941X
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About
Contact & Profiles
Research Areas
  • Brain Metastases and Treatment
  • Glioma Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • Neuroendocrine Tumor Research Advances
  • Meningioma and schwannoma management
  • Neurological disorders and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Neurofibromatosis and Schwannoma Cases
  • Transcranial Magnetic Stimulation Studies
  • Pituitary Gland Disorders and Treatments
  • Vascular Malformations Diagnosis and Treatment
  • Medical and Biological Sciences
  • Head and Neck Surgical Oncology
  • Cancer, Stress, Anesthesia, and Immune Response
  • Congenital Heart Disease Studies
  • Neuroscience and Neural Engineering
  • Genetic Neurodegenerative Diseases
  • Mathematical Biology Tumor Growth
  • Neuroscience and Neuropharmacology Research
  • Intracranial Aneurysms: Treatment and Complications
  • Cerebral Venous Sinus Thrombosis
  • Cardiovascular Issues in Pregnancy
  • Cervical and Thoracic Myelopathy
  • Surgical site infection prevention
  • Spinal Dysraphism and Malformations

Hôpital Pellegrin
2015-2025

Centre Hospitalier Universitaire de Bordeaux
2014-2025

Institut de Mathématiques de Bordeaux
2023-2025

Université de Bordeaux
2014-2025

Institut Polytechnique de Bordeaux
2023-2025

Centre National de la Recherche Scientifique
2020-2025

Inserm
2024-2025

Neurocentre Magendie
2025

FHU Neurovasc
2024

Institut de Psychiatrie et Neurosciences de Paris
2024

Objective: Asleep deep brain stimulation (DBS) for Parkinson’s disease (PD) is being performed more frequently; however, motor outcomes and safety of asleep DBS have never been assessed in a prospective randomized trial. Methods: We conducted prospective, randomized, noncomparative trial to assess the DBS. Leads were implanted subthalamic nucleus (STN) according probabilistic stereotactic coordinates with surgical robot under O-arm© imaging guidance either general anesthesia without...

10.1159/000511424 article EN Stereotactic and Functional Neurosurgery 2020-11-30

ABSTRACT Aims Embryonal tumours with PLAGL1 or PLAGL2 amplification (ET, PLAGL) show substantial heterogeneity regarding their clinical characteristics and have been treated inconsistently, resulting in diverse outcomes. In this study, we aimed to evaluate the behaviour of ET, PLAGL elucidate response pattern across different applied treatment regimens. Methods We conducted an in‐depth retrospective analysis serial imaging data 18 patients (nine each amplified). Results Patients ‐amplified...

10.1111/nan.70015 article EN cc-by Neuropathology and Applied Neurobiology 2025-04-01

Abstract High‐grade meningiomas are rare tumours that often relapse and difficult to treat, no clearly recommended systemic treatment is available. In this study, we assessed the efficacy of carboplatin–gemcitabine as a chemotherapy regimen administered patients with high‐grade recurrent after observing incidental tumour shrinkage in one patient. Carboplatin–gemcitabine was offered on compassionate basis French meningioma within framework Réunion d'orientation thérapeutique des méningiomes...

10.1002/ijc.35453 article EN International Journal of Cancer 2025-04-21

<b><i>Background:</i></b> The control of the anatomic position active contacts is essential to understand effects and adapt settings neurostimulation. localization commonly assessed by a registration between preoperative MRI postoperative CT scan. However, its accuracy depends on quality algorithm many software programs are available. <b><i>Objective:</i></b> To compare implanted deep brain stimulation (DBS) leads in subthalamic nucleus (STN)...

10.1159/000494982 article EN Stereotactic and Functional Neurosurgery 2018-01-01

The incidence of newly diagnosed meningiomas, particularly those incidentally, is continually increasing. indication for treatment empirical because, despite numerous studies, the natural history these tumours remains difficult to describe and predict.This retrospective single-centre study included 294 consecutive patients with 333 meningiomas who underwent three or more brain imaging scans. Linear, exponential, power, Gompertz models were constructed derive volume-time curves, by using a...

10.1016/j.ebiom.2023.104697 article EN cc-by-nc-nd EBioMedicine 2023-07-04

Multiple endocrine neoplasia type 1 (MEN1) is thought to increase the risk of meningioma and ependymoma. Thus, we aimed describe frequency, incidence, specific clinical histological features central nervous system (CNS) tumors in MEN1 population (except pituitary tumors).

10.1158/1078-0432.ccr-23-3308 article EN Clinical Cancer Research 2024-04-17

An increased incidence of various neoplasms has been described in patients with acromegaly, and there is evidence to suggest that growth factors are risk for the development meningiomas.To study if acromegaly more at developing intracranial meningiomas.We conducted an observational on 221 consecutive acromegalic recruited between January 1, 2000 December 31, 2015, 357 a nonsomatotropic pituitary adenoma March 2015 2016, our institution. Patients underwent gadolinium-enhanced 3D T1 brain...

10.1093/neuros/nyz438 article EN Neurosurgery 2019-09-20

<div>AbstractPurpose:<p>Multiple endocrine neoplasia type 1 (MEN1) is thought to increase the risk of meningioma and ependymoma. Thus, we aimed describe frequency, incidence, specific clinical histological features central nervous system (CNS) tumors in MEN1 population (except pituitary tumors).</p>Experimental Design:<p>The study included patients harboring CNS diagnosed with syndrome after 1990 followed up French national cohort. The standardized incidence ratio...

10.1158/1078-0432.c.7309491 preprint EN 2024-07-01
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