A5017909567- Glioma Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Neuroblastoma Research and Treatments
- Fetal and Pediatric Neurological Disorders
- Stroke Rehabilitation and Recovery
- Cerebrovascular and Carotid Artery Diseases
- Neurofibromatosis and Schwannoma Cases
- Radiology practices and education
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Venous Thromboembolism Diagnosis and Management
- Diversity and Career in Medicine
- Cerebral Venous Sinus Thrombosis
- Traumatic Brain Injury Research
- Cancer, Hypoxia, and Metabolism
- Cancer Mechanisms and Therapy
- Neurological Complications and Syndromes
- Long-Term Effects of COVID-19
- Histone Deacetylase Inhibitors Research
- High Altitude and Hypoxia
- Intracerebral and Subarachnoid Hemorrhage Research
- Health and Medical Education
- CNS Lymphoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
Fundación Santa Fe de Bogotá
2014-2024
Universidad El Bosque
2011-2021
Health Affairs
2021
Foundation for Clinical and Applied Cancer Research
2016
Moorfields Eye Hospital NHS Foundation Trust
2014
University College London
2014
Moorfields Eye Hospital
2014
Johns Hopkins Hospital
2013
The University of Texas MD Anderson Cancer Center
2013
National Institute of Mental Health and Neurosciences
2013
Purpose To compare the effectiveness of octreotide/everolimus vs. sunitinib for systemic treatment recurrent aggressive meningiomas. Methods 31 patients with or refractory WHO II III meningiomas were examined in two reference centers Colombia. Patients who had (sunitinib, everolimus/octreotide) and a complete follow-up included. Overall survival (OS), progression-free (PFS) toxicities evaluated. Additionally, tissue samples PDGFRβ VEGFR2, their expression was correlated outcomes. Results...
Objective. The aim of this study was to describe a family with cryopyrin-associated periodic syndrome (CAPS) in which the disease unveiled after ophthalmologic evaluation. Methods. Family and personal histories from each patients were recorded. Each underwent full ophthalmological examination along physical examination. mutational analysis NLRP3 gene performed by means direct sequencing. Results. proband admitted during an episode unilateral anterior uveitis. She had history recurrent red...
Chronic neuroinflammation is characterized by increased blood-brain barrier (BBB) permeability, leading to molecular changes in the central nervous system that can be explored with biomarkers of active neuroinflammatory processes. Magnetic resonance imaging (MRI) has contributed detecting lesions and permeability BBB. Ultra-small superparamagnetic particles iron oxide (USPIO) are used as contrast agents improve MRI observations. Therefore, we validate interaction peptide-88 laminin,...
Introduction: Among the confirmed cases of hydrocephalus in Middle East, there is no standardization care or differentiation between various types hydrocephalus.This first study Eastern regions that aims at developing a clinical protocol for appropriate standard care.Methods: We used well-established from Johns Hopkins University and adapted it to locally relevant context with help an interdisciplinary panel experts.The final included diagnostic radiology studies, lumbar punctures (LP) as...
Low-grade gliomas (LGGs) are classified by the World Health Organization as astrocytoma (DA), oligodendroglioma (OD), and mixed oligoastrocytoma (OA). TP53 mutation 1p19q codeletion most-commonly documented molecular abnormalities. Isocitrate dehydrogenase (IDH) 1/2 mutations frequent in LGGs; however, IDH-negative can also occur. Recent research suggests that ATRX plays a significant role gliomagenesis.We investigated p53 Olig2 protein expression, MGMT promoter methylation, codeletion, IDH,...
To evaluate and compare the clinical performance of observers interpreting head CT images from patients with symptoms acute stroke a medical workstation or smartphone laptop reading system.Our institutional review board approved this retrospective study waived requirement for informed consent. We employed factorial design including 2,256 interpretations (188 × 4 neuroradiologists 3 systems). Accuracy equivalence tests, at threshold 5% 10%, were performed following variables: detection...
Introduction The aim of this study was to assess individual regions the Alberta Stroke Program Early CT Score in noncontrast head computed tomography interpretations using a smartphone telestroke network, by comparison medical monitor. Methods review board our institution approved retrospective study. A factorial design with 188 patients, four radiologists and two reading systems used. Accuracy reliability were evaluated. Results Very good interobserver agreements observed on total for both...
The aim of this study was to evaluate the equivalence brain CT interpretations performed using a diagnostic workstation and mobile tablet computer, in telestroke service. ethics committee our institution approved retrospective study. A factorial design with 1452 used. assessed variables were type stroke classification, presence contraindications tPA administration, hyperdense intracranial artery sign (HMCA), Alberta Stroke Program Early Score (ASPECTS) score. These evaluated determine effect...
Background: Automated stroke solutions in developing countries have the potential to reduce healthcare gaps. This study assesses performance of RAPID NCCT Stroke module compared local neuroradiologists’ evaluation acute stroke. Methods: Rapid is a new multi-module AI tool that simultaneously evaluates non-contrast CT scans (NCCT) for ICH (any subtype, volume >0.4 ml), ASPECT score, and suspicion LVO (i.e., intracranial ICA or horizontal segment MCA). The software determines based on an...
Accuracy and Reliability of the Recommendation for IV Thrombolysis in Acute Ischemic Stroke Based on Interpretation Head CT a Smartphone or LaptopAntonio J. Salazar1, Nicolás Useche2, Sonia Bermúdez2, Aníbal Morillo3, Oscar Tórres2, Manuel F. Granja3, Natalia Rueda2 Brenda Ropero2Audio Available | Share Claim CREDIT
Introduction: Traumatic spinal root injury caused by shoulder dislocation may involve the brachial plexus or, in some cases, a single nerve. The degree of severity depends on many patient-specific factors as well mechanism injury. It is essential to suspect this type lesion means thorough physical examination order have better patient outcomes. Case Presentation: We presented subtle magnetic resonance imaging (MRI) findings 35-yearold male with left trauma and after falling off bicycle. He...
Se expone el caso de una mujer 19 años a quien se le realizó diagnóstico un xantoastrocitoma pleomórfico anaplásico parietooccipital izquierdo, neoplasia poco frecuente que suele presentarse en la población pediátrica y los adultos jóvenes. Dicho tumor debuta generalmente con crisis convulsivas sus características histológicas patognomónicas son pleomorfismo celular, vacuolización lipídica su citoplasma reactividad proteína ácida fibrilar glial (PAFG) S100. El estudio nuevos marcadores...
Aim: This study compares the reliability of brain CT interpretations performed using a diagnostic workstation and mobile tablet computer in telestroke context.
 Methods: A factorial design with 1,452 was used. Reliability evaluated Fleiss’ kappa coefficient on agreements interpretation results lesion classification, presence imaging contraindications to intravenous recombinant tissue-type plasminogen activator (t-PA) administration, Alberta Stroke Program Early Score (ASPECTS).
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9660 Background: Vascular endothelial growth factor-D (VEGF-D) promotes both angiogenesis and lymphangiogenesis. It plays a role in solid tumor metastatic dissemination as it is required for vascularization lymphatic development. VEGF-D expression predictive of disease extent outcome variety human malignancies. This the first study to evaluate its prognostic utility patients with localized prostate cancer treated external beam radiation therapy (EBRT). Methods: Tissue blocks were available...