Christos Papagiannopoulos
A5089846820- Colorectal Cancer Screening and Detection
- Blood Pressure and Hypertension Studies
- Genetic factors in colorectal cancer
- Nutritional Studies and Diet
- Nutrition and Health in Aging
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- RNA modifications and cancer
- Pharmacology and Obesity Treatment
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Metabolomics and Mass Spectrometry Studies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- RNA and protein synthesis mechanisms
- Hormonal Regulation and Hypertension
- Diet and metabolism studies
- SARS-CoV-2 detection and testing
- Regulation of Appetite and Obesity
- Genetic Associations and Epidemiology
- Dietary Effects on Health
- Cardiovascular Health and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Circular RNAs in diseases
- Acute Lymphoblastic Leukemia research
University of Ioannina
2022-2025
National and Kapodistrian University of Athens
2022-2024
Aristotle University of Thessaloniki
2019-2022
University Hospital of Ioannina
2022
University Medical Center Groningen
2021
University of Groningen
2021
Alzheimer's disease (AD) diagnosis relies on clinical symptoms complemented with biological biomarkers, the Amyloid Tau Neurodegeneration (ATN) framework. Small non-coding RNA (sncRNA) in blood have emerged as potential predictors of AD. We identified sncRNA signatures specific to ATN and AD, evaluated both their contribution improving AD conversion prediction beyond alone.
Abstract Background Coexisting long-term conditions (LTCs) in psoriasis and their potential causal associations with the disease are not well established. Objectives To determine distinct clusters of LTCs people bidirectional association between these psoriasis. Methods Using latent class analysis, cross-sectional data from UK Biobank were analysed to identify psoriasis-related comorbidity profiles. Linkage disequilibrium score regression (LDSR) was applied compute genetic correlation LTCs....
Excessive adiposity increases disease risk, yet the exact underlying mechanisms remain unknown. We compared sex-specific metabolic signatures (MSs) of indices (non-allometric: body fat %, waist circumference, hip waist-to-hip ratio, mass index; allometric: a shape index, waist-to-hip-index ratio) and examined their associations with 29 clinical biomarkers in 151,526 UK Biobank participants. MSs performance was validated an independent cohort. In females, mainly consisted lipoprotein particle...
Abstract Background Waist circumference (WC) and its allometric counterpart, “a body shape index” (ABSI), are risk factors for colorectal cancer (CRC); however, it is uncertain whether associations with these measurements limited to specific molecular subtypes of the disease. Methods Data from 2,772 CRC cases 3,521 controls were pooled four cohort studies within Genetics Epidemiology Colorectal Cancer Consortium. Four markers (BRAF mutation, KRAS CpG island methylator phenotype,...
<p>Association between waist circumference, proximal colon cancer, and its molecular subtypes.</p>
<p>Summary of study-specific assessment microsatellite instability (MSI) status.</p>
<p>Association between ABSI, colorectal cancer, and its molecular subtypes after conducting multiple imputation.</p>
<p>Association between waist circumference, colorectal cancer, and its molecular subtypes after conducting multiple imputation.</p>
<p>Association between waist circumference, distal colon cancer, and its molecular subtypes.</p>
<p>Association between A Body Shape Index (ABSI), distal colon cancer, and its molecular subtypes.</p>
<p>Association between A Body Shape Index (ABSI), proximal colon cancer, and its molecular subtypes.</p>
<p>Association between waist circumference, rectal cancer, and its molecular subtypes.</p>
<p>Association between A Body Shape Index (ABSI), rectal cancer, and its molecular subtypes.</p>
<p>Summary of study-specific assessment CpG Island Methylation Phenotype (CIMP) status.</p>
<div>AbstractBackground:<p>Waist circumference (WC) and its allometric counterpart, “a body shape index” (ABSI), are risk factors for colorectal cancer; however, it is uncertain whether associations with these measurements limited to specific molecular subtypes of the disease.</p>Methods:<p>Data from 2,772 cancer cases 3,521 controls were pooled four cohort studies within Genetics Epidemiology Colorectal Cancer Consortium. Four markers (<i>BRAF</i>...
<p>Diagnostic proponsity plots.</p>
<p>Association between waist circumference, colorectal cancer, and its molecular subtypes stratifying by early later-onset.</p>
<p>Forest plots. Association between (top) waist circumference (per 5 cm), (bottom) a body shape index 1-SD increase) and Jass classified types of colorectal cancer after conducting multiple imputation.</p>
<p>Association between waist circumference, ABSI, colorectal cancer, and its molecular subtypes adjusting for further covariates.</p>
<p>Diagnostic density plots.</p>
<p>Description of participating studies.</p>
<p>Supplementary Material & Method</p>
<p>Diagnostic trace plots.</p>
<p>Association between ABSI, colorectal cancer, and its molecular subtypes stratifying by early later-onset.</p>
Background Sleep traits may influence cancer risk; however, their associations with prostate (PCa), endometrial (ECa), and epithelial ovarian (EOCa) remain unclear. Methods We conducted an observational analysis using the UK Biobank cohort a two sample Mendelian randomisation (MR) to investigate association of six sleep such as duration, chronotype, insomnia, daytime napping, sleepiness, snoring PCa, ECa, EOCa risk. Cox proportional hazards models were used for analysis, while inverse...