A5091020597- Global Maternal and Child Health
- Child Nutrition and Water Access
- Maternal and Neonatal Healthcare
- Infant Development and Preterm Care
- Maternal and Perinatal Health Interventions
- Birth, Development, and Health
- Neonatal Respiratory Health Research
- Migration, Health and Trauma
- Gestational Diabetes Research and Management
- Intimate Partner and Family Violence
- Child Nutrition and Feeding Issues
- Breastfeeding Practices and Influences
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
- Child and Adolescent Health
- Food Security and Health in Diverse Populations
- Global Health Care Issues
- Health disparities and outcomes
- Adolescent Sexual and Reproductive Health
- Healthcare professionals’ stress and burnout
- Autopsy Techniques and Outcomes
- Acute Ischemic Stroke Management
- Poverty, Education, and Child Welfare
- HIV, Drug Use, Sexual Risk
- Resilience and Mental Health
Aga Khan University
2012-2024
Penn State Milton S. Hershey Medical Center
2020-2024
Johns Hopkins University
2017-2020
Instituto de Efectividad Clínica y Sanitaria
2016
Yale University
2016
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2014-2015
Indiana University – Purdue University Indianapolis
2015
RTI International
2014
Centre for Infectious Disease Research in Zambia
2014
Universidad Francisco Marroquín
2014
Of the 3.7 million neonatal deaths and 3.3 stillbirths each year, 98% occur in developing countries. An evaluation of community-based interventions designed to reduce number these is needed.With use a train-the-trainer model, local instructors trained birth attendants from rural communities six countries (Argentina, Democratic Republic Congo, Guatemala, India, Pakistan, Zambia) World Health Organization Essential Newborn Care course (which focuses on routine care, resuscitation,...
Adolescent girls between 15 and 19 years give birth to around 16 million babies each year, 11% of births worldwide. We sought determine whether adolescent mothers are at higher risk maternal perinatal adverse outcomes compared with aged 20–24 in a prospective, population-based observational study newborn low resource settings. undertook multi-country research all pregnant women defined geographic areas across 7 sites six low-middle income countries (Kenya, Zambia, India, Pakistan, Guatemala...
Because large, prospective, population-based data sets describing maternal outcomes are typically not available in low- and middle-income countries, it is difficult to monitor mortality rates over time identify factors associated with mortality. Early identification of risk essential develop comprehensive intervention strategies preventing pregnancy-related complications. Our objective was describe a multi-country dataset determine maternal, pregnancy-related, delivery postpartum...
Background Anemia affects almost two-thirds of pregnant women in developing countries and contributes to maternal morbidity mortality low birthweight. Objective To determine the prevalence anemia dietary socioeconomic factors associated with living an urban community setting Hyderabad, Pakistan. Methods This was a prospective, observational study 1,369 enrolled at 20 26 weeks gestation followed 6 postpartum. A blood sample obtained enrollment hemoglobin levels. Information on nutritional...
Objective To quantify maternal, fetal and neonatal mortality in low-and middle-income countries, to identify when deaths occur relationships between maternal stillbirths deaths.Methods A prospective study of pregnancy outcomes was performed 106 communities at seven sites Argentina, Guatemala, India, Kenya, Pakistan Zambia.Pregnant women were enrolled followed until six weeks postpartum.Findings Between 2010 2012, 214 070 220 235 (97.2%) completed follow-up.The ratio 168 per 100 000 live...
Few studies have examined the relationship between antenatal depression, anxiety and domestic violence in pregnant women developing countries, despite World Health Organization's estimates that depressive disorders will be second leading cause of global disease burden by 2020. There is a paucity research on mood disorders, their predictors sequelae among Pakistan.To determine prevalence depression evaluate associated factors, including violence, an urban community Pakistan.All living...
The effectiveness of mobile technology to improve medication adherence via customized Short Messaging Service (SMS) reminders for stroke has not been tested in resource poor areas. We designed a randomized controlled trial test the SMS on improving survivors Pakistan. This was parallel group, assessor-blinded, randomized, controlled, superiority trial. Participants were centrally fixed block sizes. Adult participants multiple medications with access cell phone and at least 4 weeks from onset...
During the post-partum period, most women wish to delay or prevent future pregnancies. Despite this, unmet need for family planning up a year after delivery is higher than at any other time. This study aims assess fertility intention, contraceptive usage and amongst who are six weeks postpartum, as well identify those greatest risk of having an during this period. Using NICHD Global Network Women's Children's Health Research's multi-site, prospective, ongoing, active surveillance system...
Early initiation of breastfeeding after birth and exclusive through six months age confers many health benefits for infants; both are crucial high impact, low-cost interventions. However, determining accurate global rates these activities has been challenging. We use population-based data to describe: (1) early (defined as within 1 hour birth) at 42 days post-partum; (2) factors associated with failure initiate post-partum. Prospectively collected from women their live-born infants enrolled...
The Global Network for Women's and Children's Health Research (Global Network) supports conducts clinical trials in resource-limited countries by pairing foreign U.S. investigators, with the goal of evaluating low-cost, sustainable interventions to improve health women children. Accurate reporting births, stillbirths, neonatal deaths, maternal mortality, measures obstetric care is critical efforts discover strategies improving pregnancy outcomes settings. Because most sites have weak...
Stillbirth rates remain nearly ten times higher in low-middle income countries (LMIC) than high countries. In LMIC, where 98% of stillbirths worldwide occur, few population-based studies have documented characteristics or care for mothers with stillbirths. Non-macerated stillbirths, those occurring around delivery, are generally considered preventable appropriate obstetric care. We undertook a prospective, observational study all pregnant women defined geographic areas across 7 sites...
Reported benefits of maternal nutrition supplements commenced during pregnancy in low-resource populations have typically been quite limited.This study tested the effects on newborn size, especially length, commencing for women ≥3 mo before conception (Arm 1), compared with same supplement late first trimester 2) or not at all (control Arm 3).Women First was a 3-arm individualized randomized controlled trial (RCT). The intervention lipid-based micronutrient supplement; protein-energy also...
Abstract Objective . To determine population‐based stillbirth rates and to whether the timing maturity of stillbirths suggest a high proportion potentially preventable deaths. Design Prospective observational study. Setting Communities in six low‐income countries (Democratic Republic Congo, Kenya, Zambia, Guatemala, India, Pakistan) one site mid‐income country (Argentina). Population Pregnant women residing study communities. Methods Over five‐year period, selected catchment areas, using...
Approximately 3 million neonatal deaths occur each year worldwide. Simple interventions have been tested and found to be effective in reducing the mortality. In order effectively implement public health interventions, it is important know rates of mortality understand contributing risk factors. Hence, this prospective, population-based, observational study was carried out inform these needs. The Global Network's Maternal Newborn Health Registry initiated seven sites 2008. administrators...
Research directed to optimizing maternal nutrition commencing prior conception remains very limited, despite suggestive evidence of its importance in addition ensuring an optimal environment the periconceptional period and throughout first trimester pregnancy. This is individually randomized controlled trial impact on birth length (primary outcome) time at which a intervention commenced: Arm 1: ≥ 3 mo preconception vs. 2: 12-14 wk gestation 3: none. 192 (derived from 480) mothers living...
Despite global improvements in maternal and newborn health (MNH), maternal, fetal mortality rates Pakistan remain stagnant. Using data from the Global Network's Maternal Newborn Health Registry (MNHR) objective of this study is to compare mortality, stillbirth levels putative risk factors between Pakistani site those other countries. collected through a multi-site, prospective, ongoing, active surveillance system track pregnancies births communities discrete geographical areas seven sites...
In high-resource settings, obstetric ultrasound is a standard component of prenatal care used to identify pregnancy complications and establish an accurate gestational age in order improve care. Whether or not use will ultimately outcomes low-resource settings unknown. This multi-country cluster randomized trial assess the impact antenatal screening performed by health staff on composite outcome consisting maternal mortality near-miss, stillbirth neonatal community settings. The utilize...
This population-based study sought to quantify maternal, fetal, and neonatal morbidity mortality in low- middle-income countries associated with obstructed labor, prolonged labor failure progress (OL/PL/FTP). A prospective, observational of pregnancy outcomes was performed at seven sites Argentina, Guatemala, India (2 sites, Belgaum Nagpur), Kenya, Pakistan Zambia. Women were enrolled delivery 6-week follow-up obtained evaluate rates OL/PL/FTP resulting from OL/PL/FTP, including: maternal...
Cesarean section (CS) rates are increasing globally with an unclear effect on pregnancy outcomes. The study objective was to quantify maternal and perinatal morbidity mortality associated CS compared vaginal delivery (VD) both within across sites in low- middle-income countries.
Objective The objective of this study was to describe the relationship between early pregnancy body mass index (BMI) and maternal, perinatal, neonatal outcomes in rural India Pakistan. Study Design In a prospective, population-based registry implemented communities Thatta, Pakistan Nagpur Belagavi, India, we obtained women's BMI prior 12 weeks' gestation (categorized as underweight, normal, overweight, obese following World Health Organization criteria). Outcomes were assessed 42 days...