- Global Maternal and Child Health
- Child Nutrition and Water Access
- Maternal and Neonatal Healthcare
- Pregnancy and preeclampsia studies
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Preterm Birth and Chorioamnionitis
- Cardiovascular Issues in Pregnancy
- Birth, Development, and Health
- Neonatal Respiratory Health Research
- Pregnancy and Medication Impact
- T-cell and Retrovirus Studies
- Diverse Music Education Insights
- Animal Disease Management and Epidemiology
- Parasite Biology and Host Interactions
- Global Health and Epidemiology
- Breastfeeding Practices and Influences
- Global Health and Surgery
- Assisted Reproductive Technology and Twin Pregnancy
- Vector-Borne Animal Diseases
- Folate and B Vitamins Research
- Global Public Health Policies and Epidemiology
- Global Health Care Issues
- Adolescent Sexual and Reproductive Health
- Cleft Lip and Palate Research
RTI International
2016-2025
National Heart Lung and Blood Institute
2024-2025
Wildlife Conservation Society Congo
2024
Thomas Jefferson University
2020-2024
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2013-2024
Jawaharlal Nehru Medical College
2023
Aga Khan University
2020-2023
Datta Meghe Institute of Medical Sciences
2023
Indiana University – Purdue University Indianapolis
2020-2023
Government Medical College
2023
Adolescent girls between 15 and 19 years give birth to around 16 million babies each year, 11% of births worldwide. We sought determine whether adolescent mothers are at higher risk maternal perinatal adverse outcomes compared with aged 20–24 in a prospective, population-based observational study newborn low resource settings. undertook multi-country research all pregnant women defined geographic areas across 7 sites six low-middle income countries (Kenya, Zambia, India, Pakistan, Guatemala...
In Brief OBJECTIVE: To compare placental lesions for stillbirth cases and live birth controls in a population-based study. METHODS: Pathologic examinations were performed on placentas from singleton pregnancies using standard protocol. Data analyzed overall within gestational age groups at delivery. RESULTS: Placentas 518 stillbirths 1,200 births studied. Single umbilical artery was present 7.7% of 1.7% births, velamentous cord insertion 5% 1.1% diffuse terminal villous immaturity 10.3% 2.3%...
Purpose This paper describes a set of recommendations that will aid universities planning to create sustainability education programs. These are not specific curriculum or programs but instead for academic institutions considering shift towards “sustainability education” in the broadest sense. The purpose this research was consider possible directions future at university level. Design/methodology/approach Through series workshops using “value focused thinking” framework, small team...
Objective To quantify maternal, fetal and neonatal mortality in low-and middle-income countries, to identify when deaths occur relationships between maternal stillbirths deaths.Methods A prospective study of pregnancy outcomes was performed 106 communities at seven sites Argentina, Guatemala, India, Kenya, Pakistan Zambia.Pregnant women were enrolled followed until six weeks postpartum.Findings Between 2010 2012, 214 070 220 235 (97.2%) completed follow-up.The ratio 168 per 100 000 live...
During the post-partum period, most women wish to delay or prevent future pregnancies. Despite this, unmet need for family planning up a year after delivery is higher than at any other time. This study aims assess fertility intention, contraceptive usage and amongst who are six weeks postpartum, as well identify those greatest risk of having an during this period. Using NICHD Global Network Women's Children's Health Research's multi-site, prospective, ongoing, active surveillance system...
Early initiation of breastfeeding after birth and exclusive through six months age confers many health benefits for infants; both are crucial high impact, low-cost interventions. However, determining accurate global rates these activities has been challenging. We use population-based data to describe: (1) early (defined as within 1 hour birth) at 42 days post-partum; (2) factors associated with failure initiate post-partum. Prospectively collected from women their live-born infants enrolled...
To describe the association of maternal anaemia with maternal, fetal, and neonatal outcomes.Prospective cohort study.Rural India Pakistan.Pregnant women residing in study catchment area.We performed an analysis a prospective pregnancy registry which haemoglobin is commonly obtained as well outcomes for 42 days post-delivery. Women 40 years or older who delivered before 20 weeks had level <3.0 g/dl were excluded. Our primary exposure was anaemia, categorised keeping World Health Organization...
The Global Network for Women's and Children's Health Research (Global Network) supports conducts clinical trials in resource-limited countries by pairing foreign U.S. investigators, with the goal of evaluating low-cost, sustainable interventions to improve health women children. Accurate reporting births, stillbirths, neonatal deaths, maternal mortality, measures obstetric care is critical efforts discover strategies improving pregnancy outcomes settings. Because most sites have weak...
Stillbirth rates remain nearly ten times higher in low-middle income countries (LMIC) than high countries. In LMIC, where 98% of stillbirths worldwide occur, few population-based studies have documented characteristics or care for mothers with stillbirths. Non-macerated stillbirths, those occurring around delivery, are generally considered preventable appropriate obstetric care. We undertook a prospective, observational study all pregnant women defined geographic areas across 7 sites...
To compare antiphospholipid antibodies in deliveries with and without stillbirth using a multicenter, population-based case-control study of stillbirths live births. Maternal sera were assayed for immunoglobulin (Ig)G IgM anticardiolipin anti-β2-glycoprotein-I antibodies. Assays performed 582 1,547 birth deliveries. Elevated levels IgG associated an approximate threefold increased odds (crude ratio [OR] 3.43, 95% confidence interval [CI] 1.79-6.60, 3.8% compared 1.1% OR 3.17, CI 1.30-7.72,...
Stillbirth rates remain high, especially in low and middle-income countries, where are 25 per 1000, ten-fold higher than high-income countries. The United Nations' Every Newborn Action Plan has set a goal of 12 stillbirths 1000 births by 2030 for all From population-based pregnancy outcome registry, including data from 2010 to 2016 two sites each Africa (Zambia Kenya) India (Nagpur Belagavi), as well Pakistan Guatemala, we evaluated the stillbirth annual decline risk factors 427,111 which...
Abstract Background Pakistan has among the poorest pregnancy outcomes worldwide, significantly worse than many other low-resource countries. The reasons for these differences are not clear. In this study, we compared in to countries and explored factors that might help explain differences. Methods Global Network (GN) Maternal Newborn Health Registry (MNHR) is a prospective, population-based observational study includes all pregnant women their defined geographic communities six low-middle...
The use of azithromycin reduces maternal infection in women during unplanned cesarean delivery, but its effect on those with planned vaginal delivery is unknown. Data are needed whether an intrapartum oral dose would reduce and offspring sepsis or death.
A specific probe for detecting ecotropic murine leukemia virus sequences was constructed by cloning a 500-base-pair DNA segment, corresponding to portion of the env region AKR virus, in pBR322/Escherichia coli K-12 host/vector system. This used screen cellular DNAs six inbred strains mice presence retroviral Southern blot hybridization procedure. Three copies viral were detected AKR/N (a high-ecotropic strain) and two found BALB/c low-ecotropic DNAs. As expected, no reactive with this NFS...
Abstract Objective . To determine population‐based stillbirth rates and to whether the timing maturity of stillbirths suggest a high proportion potentially preventable deaths. Design Prospective observational study. Setting Communities in six low‐income countries (Democratic Republic Congo, Kenya, Zambia, Guatemala, India, Pakistan) one site mid‐income country (Argentina). Population Pregnant women residing study communities. Methods Over five‐year period, selected catchment areas, using...
Approximately 3 million neonatal deaths occur each year worldwide. Simple interventions have been tested and found to be effective in reducing the mortality. In order effectively implement public health interventions, it is important know rates of mortality understand contributing risk factors. Hence, this prospective, population-based, observational study was carried out inform these needs. The Global Network's Maternal Newborn Health Registry initiated seven sites 2008. administrators...
Ultrasound is widely regarded as an important adjunct to antenatal care (ANC) guide practice and reduce perinatal mortality. We assessed the impact of ANC ultrasound use at health centres in resource-limited countries.Cluster randomised trial.Clusters within five countries (Democratic Republic Congo, Guatemala, Kenya, Pakistan, Zambia) METHODS: Clusters were standard or plus two ultrasounds referral for complications. The study trained providers intervention clusters perform basic obstetric...
Despite global improvements in maternal and newborn health (MNH), maternal, fetal mortality rates Pakistan remain stagnant. Using data from the Global Network's Maternal Newborn Health Registry (MNHR) objective of this study is to compare mortality, stillbirth levels putative risk factors between Pakistani site those other countries. collected through a multi-site, prospective, ongoing, active surveillance system track pregnancies births communities discrete geographical areas seven sites...
This population-based study sought to quantify maternal, fetal, and neonatal morbidity mortality in low- middle-income countries associated with obstructed labor, prolonged labor failure progress (OL/PL/FTP). A prospective, observational of pregnancy outcomes was performed at seven sites Argentina, Guatemala, India (2 sites, Belgaum Nagpur), Kenya, Pakistan Zambia. Women were enrolled delivery 6-week follow-up obtained evaluate rates OL/PL/FTP resulting from OL/PL/FTP, including: maternal...
Cesarean section (CS) rates are increasing globally with an unclear effect on pregnancy outcomes. The study objective was to quantify maternal and perinatal morbidity mortality associated CS compared vaginal delivery (VD) both within across sites in low- middle-income countries.