Umesh Charantimath
A5023562670- Global Maternal and Child Health
- Pregnancy and preeclampsia studies
- Child Nutrition and Water Access
- Iron Metabolism and Disorders
- Maternal and fetal healthcare
- Breastfeeding Practices and Influences
- Hemoglobinopathies and Related Disorders
- Birth, Development, and Health
- Mobile Health and mHealth Applications
- Child Nutrition and Feeding Issues
- Preterm Birth and Chorioamnionitis
- Sex and Gender in Healthcare
- Pregnancy and Medication Impact
- Child Development and Digital Technology
- Health Policy Implementation Science
- Ethics in Clinical Research
- Healthcare Systems and Reforms
- Food Security and Health in Diverse Populations
- Reproductive tract infections research
- Emergency and Acute Care Studies
- Blood Pressure and Hypertension Studies
- Syphilis Diagnosis and Treatment
- Diversity and Career in Medicine
- Advanced MRI Techniques and Applications
- Neurological and metabolic disorders
KLE University
2016-2025
Jawaharlal Nehru Medical College
2016-2025
King's College London
2019-2024
Jawaharlal Nehru Medical College Hospital
2023
Higher Education Academy
2022
Thomas Jefferson University
2021
University of Zimbabwe
2019
Government of India
2019
Health and Human Development (2HD) Research Network
2019
Sarojini Naidu Medical College
2016
Karnataka State continues to have the highest rates of maternal mortality in south India at 144/100,000 live births, but lower than national estimates 190-220/100,000 births. Various barriers exist timely and appropriate utilization services during pregnancy, childbirth postpartum. This study aimed describe patterns determinants routine emergency health care rural State, India.This was conducted 2012-2013. Purposive sampling used convene twenty three focus groups twelve individual interviews...
Background Poor representation of pregnant and lactating women people in clinical trials has marginalised their health concerns denied the maternal–fetal/infant dyad benefits innovation therapeutic research development. This mixed-methods systematic review synthesised factors affecting participation trials, across all levels ecosystem. Methods findings We searched 8 databases from inception to 14 February 2024 identify qualitative, quantitative, studies that described vaccine any setting....
Between 1990 and 2016 the number of adolescents with anemia world-wide increased by 20% to almost one in four. Iron deficiency adolescence results compromised growth, decreased cognitive function, depressed immune can increase risk negative outcomes pregnancy, especially case young adolescents. In India, despite several decades governmental investment prevention treatment, more than half women reproductive age are anemic, rates even higher adolescent population. Although awareness as a...
In 2015, an estimated 303 000 women died in pregnancy and childbirth. Obstetric haemorrhage, sepsis, hypertensive disorders of account for more than 50% maternal deaths worldwide. There are effective treatments these complications, but they require early detection by measurement vital signs timely administration to save lives. The primary aim this trial was determine whether implementation the CRADLE Vital Sign Alert education package into community facility maternity care low-resource...
Pregnancy hypertension is associated with 7.1% of maternal deaths in India. The objective this trial was to assess whether task-sharing care might reduce adverse pregnancy outcomes related delays triage, transport, and treatment. Indian Community-Level Interventions for Pre-eclampsia (CLIP) open-label cluster randomised controlled (NCT01911494) recruited pregnant women 12 clusters (initial four-cluster internal pilot) Belagavi Bagalkote, Karnataka. CLIP intervention (6 clusters) consisted...
Abstract Background Travel time to care is known influence uptake of health services. Generally, pregnant women who take longer transit facilities are the least likely deliver in facilities. It not clear if modelled access predicts fairly vulnerability seeking maternal across different spatial settings. Objectives This cross-sectional analysis aimed (i) compare travel times as a GIS environment with self-reported by Community Level Interventions for Pre-eclampsia: Mozambique, India and...
Background/Objectives: Iron deficiency anemia in pregnancy poses risks to mothers and infants. The study aims correlate maternal iron indices second trimester with cord blood outcomes. Methods: This prospective cohort was nested within the RAPIDIRON Trial (Reducing Anaemia Pregnancy India) at Jawaharlal Nehru Medical College, Karnataka, India. A total of 292 pregnant women moderate who received oral supplementation were enrolled from April 2021 May 2023. Maternal measured multiple time...
Objective To determine whether oral clindamycin reduces the risk of preterm birth (PTB) in women with abnormal vaginal microflora as evidenced by a pH ≥5.0. Design Randomised double‐blind placebo‐controlled trial. Setting Rural southern India. Population Pregnant singleton fetus between 13 +0/7 weeks and 20 +6/7 weeks. Methods were recruited during prenatal visits Karnataka, India, from October 2013 to July 2015. Women required have an elevated (≥5.0) colorimetric assessment. Participants...
Maternal deaths have been attributed in large part to delays recognition of illness, timely transport facility, and treatment once there. As community perceptions pregnancy their complications are critical averting maternal morbidity mortality, this study sought contribute the literature explore community-based understandings pre-eclampsia eclampsia. The was conducted rural Karnataka State, India, 2012–2013. Fourteen focus groups were held with following stakeholders: three leaders (n = 27),...
BackgroundIncomplete vital registration systems mean that causes of death during pregnancy and childbirth are poorly understood in low-income middle-income countries. To inform global efforts to reduce maternal mortality, we compared physician review computerised analysis verbal autopsies (interpreting [InterVA] software), understand their agreement on cause circumstances mortality categories (COMCATs) the Community-Level Interventions for Pre-eclampsia (CLIP) cluster randomised...
Pre-eclampsia is a leading cause of maternal and perinatal mortality. Evidence regarding interventions in low-income or middle-income setting scarce. We aimed to evaluate whether planned delivery between 34+ 0 36+ 6 weeks' gestation can reduce mortality morbidity without increasing complications India Zambia.In this parallel-group, multicentre, open-label, randomised controlled trial, we compared versus expectant management women with pre-eclampsia from gestation. Participants were recruited...
ABSTRACT Objective To explore factors affecting participation of pregnant women in randomised clinical trials Belagavi, Karnataka, India. Design A qualitative study using semi‐structured in‐depth interviews and focus group discussions as data collection methods. Setting Primary, secondary tertiary health facilities their community catchment areas Belagavi district. Sample Thirty‐three with workers previous participants a pregnancy‐focused trial, 12 currently who had not previously...
Background . A Nugent score > 7 has been defined as the gold standard for diagnosis bacterial vaginosis (BV), though it is resource intensive and impractical point of care testing. We sought to determine if colorimetric assessment vaginal pH can accurately predict occurrence BV. Methods performed a planned subanalysis 1,216 pregnant women between 13 0/7 19 6/7 weeks who underwent examination part randomized controlled trial. Using standardized technique, specimens were obtained two...
Globally, pre-eclampsia and eclampsia are major contributors to maternal perinatal mortality; of which the vast majority deaths occur in less developed countries. In addition, a disproportionate number morbidities mortalities due delayed access health services. The Community Level Interventions for Pre-eclampsia (CLIP) Trial aims task-shift community workers identification emergency management improve timely care. Literature revealed paucity published feasibility assessments prior initiating...
Blood pressure measurement is a marker of antenatal care quality. In well resourced settings, lower blood cutoffs for hypertension are associated with adverse pregnancy outcomes. We aimed to study the associations between thresholds and outcomes diagnostic test properties these in low-resource settings.We did secondary analysis data from 22 intervention clusters Community-Level Interventions Pre-eclampsia (CLIP) cluster randomised trials (NCT01911494) India (n=6), Mozambique Pakistan (n=10)....
The CRADLE-3 trial is a stepped-wedge randomised controlled aiming to reduce maternal mortality and morbidity by implementing novel vital sign device (CRADLE Vital Sign Alert) training package into routine maternity care in 10 low-income sites. MRC Guidance on complex interventions proposes that implementation strategies be shaped early phase piloting development work. We present the findings of three-month mixed-methodology feasibility study for this trial, describe how was informed...
Anaemia is a worldwide problem and iron deficiency the most common cause. In pregnancy, anaemia increases risk of adverse maternal, foetal neonatal outcomes. India's rate among highest in world with National Family Health Survey indicating over 50% pregnant women were affected by anaemia. Mukt Bharat-Intensified Iron Plus Initiative aims to reduce prevalence reproductive-age women, adolescents children 3% per year facilitate achievement Global World Assembly 2025 objective achieve reduction...
Abstract Background Iron-deficiency anemia is a known risk factor for several adverse perinatal outcomes, but data on its impact specific maternal morbidities less robust. Further, information associations between in early pregnancy and subsequent outcomes are understudied. Methods The study population was derived from the Community Level Interventions Pre-eclampsia (CLIP) trial Karnataka State, India (NCT01911494). Included were women who enrolled either arm, delivered by end date, had...