A5060950502- Ear Surgery and Otitis Media
- Nasal Surgery and Airway Studies
- Ear and Head Tumors
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Sinusitis and nasal conditions
- Mesenchymal stem cell research
- Respiratory and Cough-Related Research
- Hearing Loss and Rehabilitation
- Congenital Ear and Nasal Anomalies
- Salivary Gland Tumors Diagnosis and Treatment
- Voice and Speech Disorders
- Oropharyngeal Anatomy and Pathologies
- Noise Effects and Management
- Head and Neck Anomalies
- Facial Nerve Paralysis Treatment and Research
- Mycobacterium research and diagnosis
- Meningioma and schwannoma management
- Hearing, Cochlea, Tinnitus, Genetics
- Olfactory and Sensory Function Studies
- Head and Neck Cancer Studies
- Infectious Diseases and Mycology
- Planarian Biology and Electrostimulation
- Vestibular and auditory disorders
- Dysphagia Assessment and Management
Charles University
2014-2024
University Hospital Hradec Králové
2014-2024
University of Hradec Králové
2022-2024
This study demonstrates morphological changes in the nasal mucosa as a consequence of functional cavity after total laryngectomy (TLE).Observation patients TLE.A cohort observational contained 30 TLE. These underwent endoscopy and cytological microbiological examination mucosa. The control group comprised patients.In who TLE, occurred hyperplasia cells basal zone was most remarkable change difference statistically significant (p=0.0002) comparison with group. No shown incidence squamous cell...
Balloon Eustachian tuboplasty (BET) appears to be a promising therapeutic option for tube dysfunction. However, data are lacking on its effect in adults with chronic otitis media effusion (COME) and whether it should combined tympanocentesis. The aim of our study was determine if there is beneficial BET tympanocentesis compared only provide the COME.Randomized clinical trial.Tertiary referral hospital.Adults COME lasting more than 6 months after tympanostomy exclusion. Among 40 eligible...
Objectives: Balloon eustachian tuboplasty (BET) is a promising therapeutic option for tube (ET) dysfunction. However, data are lacking on the effect of BET in adults with symptoms chronic ET dysfunction but without contributing pathology. This study investigated adult patients only Methods: prospective clinical trial included aerated physiological middle ears and more than 6 months. Compliance follow-up was 93.3%. We evaluated effects tympanometry, assessment Valsalva or Toynbee maneuver...
Canal wall down mastoidectomy is one of the most effective treatments for cholesteatoma. However, it results in anatomical changes external and middle ear with a negative impact on patient's quality life. To provide complete closure mastoid cavity normalize anatomy ear, we used human multipotent mesenchymal stromal cells (hMSCs), GMP grade, guinea pig model. A method preparing biomaterial composed hMSCs, hydroxyapatite, tissue glue was developed. Animals from treated group were implanted...
Abstract This study investigates the incidence of temporary and permanent recurrent laryngeal nerve palsy (RLNP) possible risk factors for patients with different types thyroid gland diseases. 1224 consecutive who underwent thyroidectomy treatment various diseases between years 2001–2005. The rates RLNP were evaluated. surgeon type disorder recognised as RLNP. temporary/permanent whole group was 4.5/0.8%. groups, classified multinodular goitre, Graves’ disease, cancer or Hashimoto’s disease...
Mucocutaneous mycotic infections are common complications in patients on IL-17 inhibitor therapy. We report a case of 33-year-old male with severe psoriasis and psoriatic arthritis secukinumab combined methotrexate prednisone swelling, otorrhea, pain the right ear external auditory canal. Due to progressive hypacusis, surgical solution was chosen. Tissue samples taken during surgery revealed presence Aspergillus fumigatus. Aspergillosis should be suspected prolonged especially...
Background: This study focuses on the hearing threshold for bone conduction (BC) after middle-ear surgery. Methods: A total of 92 patients (120 ears) were treated newly diagnosed chronic otitis media with cholesteatoma (2013−2018). BC was examined at frequencies 0.5, 1, 2, and 4 kHz prior to 1 year STAM classification location, EAONO/JOS stage, surgery according SAMEO-ATO applied. The compared individual in occurrence/absence different locations. Results: For occurrence attic (A), a...
Viktor Chrobok, Michal Homoláč, Jana Krtičková, Lukáš Školoudík, Miroslava Hloušková, Lenka Bilinová, Eva Čelakovská, Vít Blanař, Jan Malý, Pavel Komínek, Karel Hejduk, Renata Chloupková, Tomáš Májek, Jitka Jírová, Jakub Dršata
Background: During otosclerosis surgery, operative trauma can lead to decreased bone conduction. Aims: The study aims observe the conduction changes after operations and analyse possible factors affecting postoperative decrease in Material Methods: Authors retrospectively processed data of 109 patients evaluated pure tone audiometry before surgery consequently 2 days, 1 month year surgery. Results: We noted a deterioration >5 dB on second day 28% (30/109) patients, which persisted one 9%...
Abstract
Introduction: Nontuberculous mycobacterial (NTM) infection of lymph nodes in young children is a rare disease. The increasing incidence has been observed after termination vacciation Czech Republic November 2010. Aim the study: To provide an overview clinical picture, dia gnostic options and therapeutic approach with neck aff ected by non-tuberculous mycobacteria. Methods: Retrospective cohort study patients confi rmed NTM treated at Clinic Otorhinolaryngology Head Neck Surgery Faculty...
Pseudogout is characterized by the deposition of calcium pyrophosphate dihydrate crystals (CPPD), primarily affecting large joints. Extra‐articular manifestations, particularly in head and neck region, are exceedingly rare. We report a unique case bilateral isolated pseudogout middle ear manifesting with progressive conductive hearing loss as first only symptom pseudogout. Otoscopy CT scan often yield differential diagnosis that includes tumors or cholesteatoma, necessitating surgery...
Abstract The relationship of sinusitis and paranasal sinus mucoceles to optic neuritis (ON) remains a challenge for both the otolaryngologist ophthalmologist. Currently, ON is assumed be rare complication diseases. Three new cases associated with diseases are described. We postulate different pathophysiologic mechanisms in our three patients: compression nerve due sphenoid mucocele first patient; extension bacterial infection second invasion aspergillosis orbital apex third patient. assume...
In the cholesteatoma surgery ossicles can be replaced to reconstruct middle ear function. It is important that these are free of squamous epithelium, prevent residual disease. This study focuses on histological findings malleus and incus harvested during surgery.Eighty ears were examined in vivo histologically consider relationship ossicles, grade bone destruction invasion deeper layers bone.Serious ossicular was observed more frequently compared (p=0.0065). Difference between children...
Background. The availability and development of methods testing the vestibuloocular reflex (VOR) brought a broader view into lateral semicircular canal (L-SCC) function. However, higher number evaluated parameters makes more difficult specialist’s diagnose-making process. Purpose. To provide medical specialists, new diagnostic-graphic tool, Estimated Vestibulogram- EVEST, enabling quick easy-to-read visualization comparison VOR test results within L-SCC. Methods. EVEST involved 148...
Postižení krčních uzlin netuberkulózní mykobakteriózou je v České republice stále vzácné onemocnění, ale jeho incidence posledních letech prudce stoupá.Nárůst počtu nemocných dětí