Abstract Background Postoperative nausea and vomiting (PONV) is a significant problem following paediatric surgery, volatile anaesthetics are an important cause of this phenomenon. BIS-guided anaesthesia, by reducing the consumption anaesthetics, leads to decrease in PONV adult patients. Study objective Evaluate role anaesthesia incidence PONV. Design Prospective, randomized, double-blind study. Setting A single center study university hospital Czech republic, from June 2021 November 2022....

Emergence delirium (ED) is a postoperative complication in pediatric anesthesia characterized by perception and psychomotor disorder, with negative impact on recovery. As the use of inhalation associated higher incidence ED, we investigated whether titrating depth general BIS monitor can reduce ED. Randomized, prospective, double-blind. Patients undergoing endoscopic adenoidectomy under according to uniform protocol. A total 163 patients both sexes aged 3-8 years were enrolled over 18...

Abstract Objective Repetitive transcranial magnetic stimulation ( rTMS ) is currently being tested for suppressing the symptoms of subjective chronic primary tinnitus, although its effect controversial. The aim this randomized double‐blinded controlled trial was to determine with unique settings tinnitus treatment. Methods Fifty‐three adult patients suffering from unilateral or bilateral nonpulsatile at least 6 months were randomly assigned (group 1, n = 20), sham 2, 12), medicament therapy...

Background: The PeptestTM is a non-invasive diagnostic test for measuring the pepsin concentration in saliva, which thought to correlate with laryngopharyngeal reflux (LPR). aim of this study was investigate value Peptest detecting LPR based on 24-h multichannel intraluminal impedance-pH (MII-pH) monitoring using several hypopharyngeal episodes as criterion LPR. Methods: Patients suspected were examined Reflux Symptom Index (RSI), Finding Score (RFS), fasting Peptest, and MII-pH monitoring....

The human papillomavirus (HPV) causes recurrent respiratory papillomatosis (RRP). Although HPV prevalence is high, the incidence of low. Thus, factors other than infection probably contribute to RRP. This study investigated whether patients with are more often infected herpes simplex virus type 2 and chlamydia trachomatis (ChT) laryngopharyngeal reflux (LPR) occurs in this group often.Prospective case-control study.Department Otorhinolaryngology University Hospital.The included 20...

Objectives Mulberry‐like changes of the posterior inferior nasal turbinate (MPINT) can lead to obstruction. Extraesophageal reflux (EER) characterized by lower pH causes mucosal inflammation and therefore contribute sinonasal pathologies. No prior studies have objectively examined possible association between acidic MPINT formation. Therefore, this study is aimed investigate 24‐h pharyngeal value in patients with MPINT. Study design Prospective case–control multi‐center study. Methods...

OBJECTIVE: Recently, a 24-h impedance was used to detect laryngopharyngeal reflux (LPR). However, not every case of LPR is pathological. Thus, pathological pharyngeal values need be clearly established diagnose LPR. The aim our study establish pharyngoesophageal impedance/pH for the diagnosis METHODS: conducted in tertiary care setting. A total 30 patients who were referred microlaryngoscopy laryngeal pathology that might caused by included this prospective study. All off proton-pump...

To the authors' knowledge, no prior studies have examined association between inferior turbinate hypertrophy (ITH) and extraesophageal reflux (EER). If EER were a cause or cofactor of ITH, antireflux treatment can be considered to surgical intervention.To evaluate presence severity in patients with different degrees ITH.Prospective multicentric cohort study conducted at 3 referral centers treating certified for 24-hour monitoring oropharyngeal pH. The was performed October 2020 2021. A total...

The aim of this study was to determine the severity extraesophageal reflux (EER) in patients with various degrees chronic rhinosinusitis (CRS), and particularly simultaneous bronchial asthma. Patients different CRS were invited participate study. Group I consisted without nasal polyps or asthma; group II but III age, gender, Reflux Symptom Index, EER evaluated using Restech system, number previous functional endoscopic sinus surgeries (FESSs) compared between groups. A total 90 (30 each...

Objectives . Detection of extraesophageal reflux (EER) in children with chronic otitis media effusion (OME) using three different diagnostic methods. Methods Children between 1 and 7 years OME who underwent adenoidectomy myringotomy insertion a ventilation tube were included this prospective study. EER was detected methods: oropharyngeal pH monitored for 24 hours the Restech system; detection pepsin middle ear fluid obtained during done Peptest, an adenoid specimen immunohistochemically....

Balloon Eustachian tuboplasty (BET) appears to be a promising therapeutic option for tube dysfunction. However, data are lacking on its effect in adults with chronic otitis media effusion (COME) and whether it should combined tympanocentesis. The aim of our study was determine if there is beneficial BET tympanocentesis compared only provide the COME.Randomized clinical trial.Tertiary referral hospital.Adults COME lasting more than 6 months after tympanostomy exclusion. Among 40 eligible...

Human papillomavirus (HPV) causes juvenile-onset recurrent respiratory papillomatosis (JORRP). Although HPV is common in children, the prevalence of JORRP low. It likely that other factors contribute to pathogenesis JORRP, during either activation or reactivation a latent infection. There evidence laryngopharyngeal reflux (LPR) might be such risk factor for adult-onset papillomatosis. This study investigated if LPR also JORRP.Children with larynx required microlaryngoscopy at tertiary...

Objectives: Balloon eustachian tuboplasty (BET) is a promising therapeutic option for tube (ET) dysfunction. However, data are lacking on the effect of BET in adults with symptoms chronic ET dysfunction but without contributing pathology. This study investigated adult patients only Methods: prospective clinical trial included aerated physiological middle ears and more than 6 months. Compliance follow-up was 93.3%. We evaluated effects tympanometry, assessment Valsalva or Toynbee maneuver...

Passage of nasal airflow during breathing is crucial in achieving accurate diagnosis and optimal therapy for patients with disorders. Computational fluid dynamics (CFD) the dominant method simulating studying airflow. The present study aimed to create a CFD model determine major routes through cavity thus help individualization surgical treatment three-dimensional was based on computed tomography scans an adult patient without problems. showed main inferior meatus part common meatus, but...

Juvenile-onset recurrent respiratory papillomatosis (JORRP) is the most common pediatric neoplastic disease of airway. Its estimated annual incidence 0.17–1.34 per 100,000 children. Although multiple treatment strategies for JORRP exist, surgical debulking remains therapeutic mainstay. In last 10 years, vascular endothelial growth factor (VEGF) inhibitor, bevacizumab, has been administered to adults and children with severe disease, it shown promising effects. For aggressive laryngeal...

Human papillomavirus (HPV) causes adult-onset recurrent respiratory papillomatosis (AORRP), but AORPP prevalence is much lower than HPV prevalence. Thus, infection necessary, not sufficient, to cause AORRP and other factors likely contribute its pathogenesis. The present study aimed investigate whether co-infection with herpetic viruses may the pathogenesis of AORRP.Prospective case-control conducted from January 2018 November 2019.Tertiary referral centre.Eighteen consecutive patients 18...

Abstract Purpose To evaluate voice quality evolution after a transoral laser cordectomy (TLC) for precancerous lesions and early glottic cancer. Methods This prospective study enrolled 18 patients scheduled TLC high-grade dysplasia, Tis, T1, T2 squamous cell cancers, from May 2017 to March 2020. Patients were grouped according the extent of TLC: Group I ( n = 11, 61.1%): unilateral subepithelial or subligamental cordectomy; II 7, 38.9%): transmuscular, total, extended cordectomy. Voice...

Abstract Purpose We evaluated the efficiency and toxicity of stereotactic hypofractionated boost in combination with conventionally fractionated radiotherapy treatment advanced floor mouth cancer. Methods Thirty-seven patients stage cancer, histologically confirmed squamous cell carcinoma (p16 negative) ineligible for surgical treatment, were indicated radiochemotherapy or hyperfractionated accelerated (HART). The protocol combined external beam (EBRT) a to primary tumor. dose delivered from...

Background During the past decade, extraesophageal reflux (EER) has been hypothesized to be one of possible factors that contribute worsening chronic rhinosinusitis (CRS). However, relationship remains indeterminate due its complexity, and it is not clear whether antireflux treatment indicated for patients with recurrent CRS who would benefit from it. Objective The aim study was determine severity EER in variable durations different numbers previous endoscopic endonasal surgeries (EES)....

Drug-induced sleep endoscopy (DISE) reveals epiglottic collapse to be a frequent cause of obstructive apnea (OSA) and intolerance positive airway pressure (PAP). These patients require different management. This prospective study aimed compare transoral laser epiglottopexy outcomes in with OSA caused by the patients’ previous PAP outcomes. Fifteen consecutive adult during DISE were included; ten analyzed. Before inclusion, was indicated ineffective six patients, one whom underwent...

Here, we report a unique case in which fibroepithelial polyp was found the cartilaginous part of external auditory canal 2-year-old child. The successfully treated by excision using an endaural approach and healed without complications. This is very first pediatric population. Although extremely rare diagnosis, it should be considered differential diagnosis child’s polyp.