Waste resulting from edible plants is considered one of the best sources valuable phytochemicals. A promising approach for using these appreciated wastes extracting precious medically important constituents, example, free quercetin. Two new cost-effective and green extraction methods are introduced in present study: ultrasound-assisted glycerol (UAGE) microwave-assisted (MAE). These protocols optimized factorial design to define highest yield extraction, HPLC-UV at 370 nm was used as a...

Green and sustainable scientific research is crucial for health environmental improvement. Electrochemical analysis simplifies complex processes, saving time cost. Ion selective electrode method, a key in green analytical chemistry, was utilized. A highly solid contact sensor developed two applications, detecting cinnarizine (CIN) dimenhydrinate (DMH) pharmaceuticals, identifying CIN diphenhydramine (DIP) human plasma. Careful selection of ionophores ensured accurate detection. Multi-wall...

Antazoline ( ANT ) is a H1 histamine receptor antagonist having anticholinergic properties used to decrease nasal congestion. It found in eye drops usually combination with either tetryzoline TET) or xylometazoline XLO ). In this work, novel electrochemical sensor based on carbon paste electrode (CPE) developed for simple, rapid, sensitive, and selective determination of antazoline pure form, different pharmaceutical formulations presence aqueous humor. CPE modified nanoparticles multiwalled...

Abstract Background The heterocyclic compounds are extremely important with wide array of synthetic, pharmaceutical, and industrial applications. Heterocyclic-containing have been reported for their broad spectrum biological activities including antibacterial, antifungal, antiviral, antiprotozoal, anthelmintic activity. Main text Several techniques used the quantitation in pharmaceutical samples such as high-performance liquid chromatography (HPLC) either equipped UV-visible or fluorescence,...

Solid contact ion-selective electrodes (SC-ISEs) have created a new, promising field in pharmaceutical and biological analysis, recognized as an energy-saving, straightforward, environmentally friendly technique. Hence, the present study, miniaturized solid-contact sensors been fabricated well designed for simultaneous in-line quantification of cationic amlodipine (AML) anionic valsartan (VAL) binary ternary mixtures with hydrochlorothiazide (HCT). A screen-printed carbon electrode PVC...

Abstract Different sensitive and selective spectrophotometric methods for the determination of ofloxacin dexamethasone in their binary mixture were presented. Ofloxacin was determined simply by zero order at its λmax 293.4 nm a linear range 1.5–12 μg mL−1 with mean percentage recovery 100.07 ± 0.66% without any interference even low or high concentrations. Dexamethasone first derivative ratio spectra 1DD 266.5 nm, subtraction centering 243 nm 2.5–27.5 μg mL−1 recoveries 100.09 ± 0.70%,...

Extraction is the leading critical stage in analysis of nutraceuticals. Ginkgo biloba (GB) has gained interest because its therapeutic usages.The aim was to develop four cost-effective extraction techniques for quercetin from GB a sachet containing mixture These are solid-phase (SPE), liquid-liquid extraction, inverted dispersive microextraction, and QuEChERS (quick, easy, cheap, effective, rugged, safe) method.Direct spectrophotometry used monitor recovery standard throughout optimization...

Phenazopyridine hydrochloride (PHZ) and Trimethoprim (TMP) are formulated together to treat urinary tract infections. The present work represents the first electrochemical sensor simultaneously determine with good anodic peak potential separation. A rapid, simple sensitive oxidation based on using multiwalled carbon nanotubes (CNT) sugar polymer (PS) as modifier paste (CNT/PS/MCPE) is described. method was developed validated in accordance guidelines of International Council for...

Valaciclovir hydrochloride (VAL) is an essential antiviral prodrug used to cure various types of herpes. Analysis VAL by different analytical techniques demonstrates a persuasive aspect that favorable in quality control application.This study describes comparison between colorimetric and chromatographic (RP-high performance liquid chromatography (HPLC) thin-layer (TLC)-densitometric) methods concerning selectivity specificity for the determination all possible degradation products (alkali-...

Two sensitive and selective methods were developed for the simultaneous determination of four commonly used non-steroidal anti-inflammatory drugs (NSAIDs), namely; paracetamol (PCM), diclofenac sodium (DCF), ibuprofen (IBP), indomethacin (IND) in wastewater effluents.The first method HPLC studied using a mobile phase consisting phosphate buffer (pH 3.0) acetonitrile at flow rate 1 mL/min.in gradient elution mode detection 220 nm.The separation process was performed on BDS Hypersil Cyano...

Activated platelets-rich plasma (A-PRP) was used extensively in various experimental and clinical models. However, the use of anticoagulant A-PRP preparation may interfere with healing process. Second generation were developed without adding anticoagulants or activators which where know as platelet rich fibrin (PRF). The PRF improved during known advanced-PRF (A-PRF). In vitro studies, A-PRF showed releasing significantly higher growth factors over time than however, limited studies document...

This work was conducted during 2020 and 2021 growing seasons on selected guava trees (8 years old) planted apart at (3 x 3 m) using traditional irrigation, a Randomized Block Design with plantfor each genotype.These received the recommended management private orchards in Alexandria, Qaluobyia El-Beheira governorates as well El Sabahia Research Station Laboratory.Theobjective of this is to be assess best genotype from four genotypes concerning vegetative, flowering, fruit quality yield.The...