A5031964745- Analytical Methods in Pharmaceuticals
- Analytical Chemistry and Chromatography
- Antibiotics Pharmacokinetics and Efficacy
- Analytical Chemistry and Sensors
- Pesticide Residue Analysis and Safety
- Electrochemical sensors and biosensors
- Analytical chemistry methods development
- Computational Drug Discovery Methods
- Chemistry and Chemical Engineering
- Spectroscopy and Chemometric Analyses
- Electrochemical Analysis and Applications
- Pharmaceutical and Antibiotic Environmental Impacts
- Pharmaceutical Quality and Counterfeiting
- Advanced Chemical Sensor Technologies
- Essential Oils and Antimicrobial Activity
- Carbon and Quantum Dots Applications
- Microscopic Colitis
- Crystallization and Solubility Studies
- COVID-19 and Mental Health
- Forensic Fingerprint Detection Methods
- Heavy Metals in Plants
- Phytochemicals and Antioxidant Activities
- Chemical and Physical Properties in Aqueous Solutions
- Phenothiazines and Benzothiazines Synthesis and Activities
- Drug Solubulity and Delivery Systems
Syrian Private University
2023-2024
University of Aleppo
2019-2021
The cutting-edge combination of aspirin (ASA) and sildenafil citrate (SIC) has been presented as a suggested dosage form for the treatment thin endometrium erectile dysfunction, particularly in patients with cardiovascular diseases. However, ASA is highly sensitive to degradation into its major deterioration product, known salicylic acid (SA). Consequently, it eminently essential evolve approaches synchronous quantification SIC presence SA.The main objective this work develop three SA their...
Cardiovascular disorders are among the leading causes of death worldwide, especially hypertension, a silent killer syndrome requiring multiple drug therapy for appropriate management. Hydrochlorothiazide is an extensively utilized thiazide diuretic that combines with several antihypertensive drugs effective treatment hypertension. In this study, sustainable, innovative and accurate high performance liquid chromatographic methods diode array tandem mass detectors (HPLC-DAD LC-MS/MS) were...
Single tablet regimens (STRs) for hypertension suppression improve patient satisfaction, quality of life, medication and adherence compared to multi-tablet (MTRs). Development simple cost effective at the same time green an ecofriendly method analysis resolution multicomponent complex mixtures is increasingly important issue in field pharmaceutical industry general analytical chemistry specific. Thus, presented research deals with two main goals, first one concerned developing applying a...
Rifaximin (RFX) is a non-absorbable antibiotic with broad-spectrum efficacy. It treats travelers’ diarrhea, irritable bowel syndrome, non-systematic bacterial infections, overgrowth and enteric infections. In this work, carbon dots prepared from Ziziphus spina-christi leaves’ powders are utilized as green fluorometric biosensor for the assessment of RFX. The morphological lineaments were recognized by using TEM SEM techniques. manifest fluorescence emission peak at 432 nm after an excitation...
Abstract This study aims to prefer the suitability of an analytical approach developed for simultaneously determining ciprofloxacin hydrochloride (CIP) and hydrocortisone (HYD) in their ear drop dosage form. The preference between three known instruments was utilized, namely UV-spectrophotometry, reversed phase-high-performance liquid chromatography (RP-HPLC)-UV, thin-layer (TLC)-densitometry. instrumentational studies determined that mathematical UV methods (utilized various manipulation...
Green and sustainable scientific research is crucial for health environmental improvement. Electrochemical analysis simplifies complex processes, saving time cost. Ion selective electrode method, a key in green analytical chemistry, was utilized. A highly solid contact sensor developed two applications, detecting cinnarizine (CIN) dimenhydrinate (DMH) pharmaceuticals, identifying CIN diphenhydramine (DIP) human plasma. Careful selection of ionophores ensured accurate detection. Multi-wall...
This study presents a sustainable electrochemical investigation of pramipexole (PRA) in pharmaceuticals and human plasma, using cyclic differential pulse voltammetry. Key parameters, including potential range, buffer pH, accumulation period, scan rate were optimized, establishing efficient voltammetric methods for PRA analysis. The analytical range was 0.60–12.00 μ g ml −1 , with detection limit 0.14 correlation coefficient 0.9998. Recovery rates ranged from 98.60 ± 0.26% to 101.33 0.38%,...
Six spectrophotometric methods were developed to determine a new single-dose otic solution known as “Otovel®,” which consists of two components: the major one is ciprofloxacin (CIP) and minor fluocinolone acetonide (FLU). The ratio (FLU) in Otovel® 12 : 1, considered challengeable for UV determination. Thus, spectrum addition sample enrichment technique was required analysis low concentration. All these capable resolving spectra each component D 0 belonging fingerprint resolution technique....