A5022862433- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Lipoproteins and Cardiovascular Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Health and Disease Prevention
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Disease and Adiposity
- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Heart Failure Treatment and Management
- Blood Pressure and Hypertension Studies
- Stoma care and complications
- Advanced MRI Techniques and Applications
- Adipokines, Inflammation, and Metabolic Diseases
- Climate Change and Health Impacts
- Cardiac Valve Diseases and Treatments
- Galectins and Cancer Biology
- Eicosanoids and Hypertension Pharmacology
- Conducting polymers and applications
- Heart Rate Variability and Autonomic Control
- Parathyroid Disorders and Treatments
Shinshu University
2024-2025
Ome Municipal General Hospital
2024
Kumamoto University
2013-2022
SUNY Downstate Health Sciences University
2022
State University of New York
2022
Kumamoto University Hospital
2014-2020
Fukuoka University
2020
Weatherford College
2019
Suzuki (Japan)
2019
Providence College
2018
Background Endothelial dysfunction is a key component of vascular vulnerability. Reactive hyperemia index ( RHI ), as assessed by the peripheral arterial tonometry, can noninvasively evaluate endothelial function. This study was designed to determine additional prognostic value function Synergy Between PCI With Taxus and Cardiac Surgery Score SYNTAX sc) Framingham Risk FRS ) in predicting cardiovascular events high‐risk patients. Methods Results We undertook two‐center prospective 528 stable...
Sirt (Sirtuin) 7, the most recently identified mammalian sirtuin, has been shown to contribute appropriate wound healing processes after acute cardiovascular insult. However, its role in development of cardiac remodeling pressure overload is unclear. Cardiomyocyte-specific Sirt7-knockout and control mice were subjected induced by transverse aortic constriction. Cardiac hypertrophy functions then examined these mice. Sirt7 protein expression was increased myocardial tissue overload....
Angina without significant stenosis, or nonobstructive coronary artery disease, attracts clinical attention. Microvascular spasm (microvascular CAS) can cause disease. We investigated the features of microvascular CAS and therapeutic efficacy calcium channel blockers.Three hundred seventy consecutive, stable patients with suspected angina presenting arteries (<50% diameter) in angiography were intracoronary acetylcholine provocation test, simultaneous measurements transcardiac lactate...
Statin therapy reduces the risk of cardiovascular events in patients with obstructive coronary artery disease. The aim present study was to determine effects statins on prognosis vasospastic angina (VSA) free significant atherosclerotic stenosis.After exclusion 475 from 1877 consecutive who underwent an acetylcholine-provocation test between January 1991 and December 2010, data 640 VSA without organic stenosis remaining 1402 were analyzed retrospectively. Propensity score matching performed...
Abstract Background The H2FPEF score is recognized as a simple method to diagnose heart failure (HF) with preserved left ventricular ejection fraction (HFpEF). We investigated the value of in predicting subsequent cardiovascular events HFpEF patients. Methods This study was retrospective, single-center, observational study. calculated scores for 404 consecutive Subjects were subdivided into low- (0–3), intermediate- (4–6), and high-score (7–9) groups followed 50 months. primary secondary...
With the advancement in successfully treating different types of cancers, there is an immediate and increased need to focus on risk complexity cardiovascular events cancer survivors. This has led emergence onco-cardiology/cardio-oncology field. We examined varying incidence after percutaneous coronary intervention (PCI) patients with or without cancer.Participants were divided into a non-malignant group malignant group, consisting who receiving had ever received treatment. The primary...
Background:Endothelial dysfunction plays a crucial role in heart failure (HF), but the association between peripheral microvascular endothelial function assessed by reactive hyperemia arterial tonometry (RH-PAT) and prognosis remains unknown HF with reduced left ventricular (LV) ejection fraction (HFREF). We prospectively investigated HF-related near-future cardiovascular outcomes HFREF patients.Methods Results:The 362 patients (LVEF <50%) were followed for events (composite of death...
Air pollution including particulate matter with an aerodynamic diameter ≤2.5 µm (PM2.5) increases the risk of acute myocardial infarction. However, whether short-term exposure to PM2.5 triggers onset infarction nonobstructive coronary arteries, compared artery disease, has not been elucidated. This study aimed estimate association between and admission for infarction, arteries.This was a time-stratified case-crossover multicenter validation study.This used nationwide administrative database...
In a survey of intestinal bacteria capable metabolizing glycyrrhizin (GL), Ruminococcus sp. PO1-3 and Clostridium innocuum ES24-06 were isolated from human feces. The former strain had the ability to hydrolyze GL glycyrrhetic acid (GA) reduce 3-dehydroglycyrrhetic (DGA) GA while latter DGA 3-epiglycyrrhetic (EGA). A mixture two strains could not only both EGA, but also epimerize EGA vice versa, possibly through 3-dehydro intermediate.
Background Non–vitamin K antagonist oral anticoagulants are used to prevent thromboembolism in patients with atrial fibrillation. The T‐ TAS “Total Thrombus‐formation Analysis System” (Fujimori Kogyo Co Ltd) was developed for quantitative analysis of thrombus formation using microchips thrombogenic surfaces (collagen, platelet chip [ PL ] ; collagen plus tissue factor, atheroma AR] ). We evaluated the utility predicting periprocedural bleeding fibrillation undergoing catheter ablation ( CA...
A recent study revealed a high prevalence of transthyretin (TTR) cardiac amyloidosis (CA) in elderly patients.