A5009532031- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Systemic Sclerosis and Related Diseases
- Adhesion, Friction, and Surface Interactions
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular and Diving-Related Complications
- Ion channel regulation and function
Medtronic (United States)
2022-2025
Medtronic (Ireland)
2021
Maastricht University
2010-2016
Early recurrence of atrial tachyarrhythmias (ERAT) within 3 months thermal ablation for fibrillation (AF) is common and often considered transient. Pulsed field (PFA) a nonthermal energy source in which ERAT not well described. The purpose this study was to analyze patients with AF undergoing PFA the Field Ablation Irreversibly Electroporate Tissue Treat (PULSED AF) trial. This analysis included 154 (52.4%) paroxysmal 140 (47.6%) persistent who had ≥10 rhythm assessments during 90-day...
Abstract Background and aims Early rhythm-control therapy in atrial fibrillation (AF) results higher freedom from arrhythmia (AA) recurrence improved cardiovascular outcomes. The optimal timing of Cryoballoon ablation (CBA) is unknown. Methods We evaluated AA procedure-related complications early vs. late CBA (≤12 >12 months diagnosis) patients enrolled the prospective Cryo Global Registry (121 centers 37 countries, NCT02752737). Results A total 3447 subjects were followed through 12...
ABSTRACT Introduction Freedom from recurrences of atrial tachyarrhythmia (ATA) is suboptimal after pulmonary vein isolation (PVI) in patients with persistent fibrillation (PsAF). This sub‐analysis the Cryo Global Registry sought to investigate predictors ablation success PVI using cryoballoon (CBA) for PsAF. Methods and Results ATA recurrence was defined as ≥ 30 s fibrillation, flutter or tachycardia a 90‐day blanking period through 12‐months. Univariate multivariable Cox regression analysis...
Little is known about how atrial oxygen supply responds to increased demand, and under which conditions it falls short (supply-demand mismatch). Here, we have investigated the vasodilator response, extraction, lactate production of left atrium (LA) ventricle (LV) in response pacing fibrillation (AF).Series A (n = 9 Dutch landrace pigs) was instrumented measure LA LV vascular conductance branches circumflex artery. Coronary reserve (CCR) calculated as ratio between during adenosine infusion...
Atrial fibrillation (AF), the most common atrial arrhythmia (AA), is an increasing healthcare burden in Korea. The objective of this sub-analysis Cryo Global Registry was to evaluate long-term efficacy, symptom burden, quality life (QoL), and utilization outcomes factors associated with AA recurrence Korean patients treated cryoballoon ablation (CBA).
Cryoballoon catheter ablation for the treatment of patients with symptomatic atrial fibrillation (AF) has been adopted globally, but there are limited multicenter reports 12-month outcomes in Korean patient population. This analysis evaluated clinical performance and safety cryoballoon (CBA) according to standard-of-care practices Korea.This evaluation AF was conducted within larger Cryo Global Registry, which is a prospective, multicenter, post-market registry. Freedom from ≥30-second...
Abstract Background Cryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). Although widely adopted, regional variations standards of care have not been well characterized. Methods Patients AF were enrolled the Cryo Global Registry (NCT02752737) from May 2016 to Sept 2021 at 128 sites 37 countries and treated cryoballoon according local clinical practice. Baseline patient procedural characteristics...
Background. Pulmonary vein isolation (PVI) with cryoballoon catheter ablation (CBA) is a well-established and widely adopted method for the treatment of patients atrial fibrillation (AF) to prevent recurrences AF. CBA adoption in South Africa (SA) outcome data SA are limited.Objectives. To evaluate real-world usage, safety effectiveness SA. Methods. In this sub-analysis Cryo Global Registry, 81 participants paroxysmal AF (PAF) persistent (PsAF) were enrolled between 2017 2021 across two...
Background: Cryoablation is superior to antiarrhythmic drugs (AAD) for the prevention of arrhythmia recurrence in drug naïve (first-line) patients with paroxysmal atrial fibrillation (AF). The adoption and outcomes first-line cryoablation a real-world setting are unknown. Purpose: To describe global usage, safety, efficacy, healthcare utilization treated management AF. Methods: Cryo Global Registry (NCT02752737) an ongoing, prospective, multicenter registry. AF index cryoballoon ablation...