A5057926346- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Allergic Rhinitis and Sensitization
- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Obstructive Sleep Apnea Research
- Ocular Infections and Treatments
- Infrared Thermography in Medicine
- Global Healthcare and Medical Tourism
- Ophthalmology and Visual Impairment Studies
- Healthcare Policy and Management
- Diversity and Career in Medicine
- Nasal Surgery and Airway Studies
- Healthcare and Venom Research
- Ocular Diseases and Behçet’s Syndrome
- Salivary Gland Disorders and Functions
- Anesthesia and Pain Management
- Cardiovascular Syncope and Autonomic Disorders
- Flavonoids in Medical Research
- Skin Protection and Aging
- Pharmaceutical industry and healthcare
- Digital Imaging in Medicine
- Acne and Rosacea Treatments and Effects
- Health Services Management and Policy
Doylestown Hospital
2016-2024
Eye Care Associates
2018-2024
Philadelphia Eye Associates
2009-2022
Temple University
2020
Harvard Eye Associates
2020
EyePoint Pharmaceuticals (United States)
2020
Takeda (United States)
2019
Ophthalmic Consultants of Long Island
2018
The Ohio State University Wexner Medical Center
2016
Ophthalmology Associates (United States)
2015
Purpose To evaluate the effects of tear osmolarity on repeatability keratometry (K) measurements in patients presenting for cataract surgery. Setting Three clinical practices. Design Observational prospective nonrandomized study. Methods Subjects were prospectively recruited based (Tearlab Osmolarity System); that is, more than 316 mOsm/L at least 1 eye (hyperosmolar) and less 308 both eyes (normal). The baseline K value was measured, a second measurement taken same instrument (IOLMaster)...
To assess the effect of oral re-esterified omega-3 fatty acids on tear osmolarity, matrix metalloproteinase-9 (MMP-9), break-up time (TBUT), Ocular Surface Disease Index (OSDI), fluorescein corneal staining, Schirmer score, meibomian gland dysfunction (MGD) stage and index in subjects with dry eyes confirmed MGD.This was a multicenter, prospective, interventional, placebo-controlled, double-masked study. Subjects were randomized to receive 4 softgels containing total 1680 mg eicosapentaenoic...
To compare the safety and efficacy of IBI-10090 anterior chamber intracameral dexamethasone drug-delivery suspension (Dexycu) with those prednisolone acetate 1.0% ophthalmic drops in treating inflammation after cataract surgery.Eleven centers United States.Prospective randomized open-label multicenter trial.Patients were 2:1 to receive a 5 μL injection 517 μg eye or topical (1 drop 4 times daily for 3 weeks). The postoperative follow-up was 90 days. primary outcome safety, evaluated by...
This study aimed to assess the effects of thermal pulsation system (TPS) treatment on astigmatism management in meibomian gland dysfunction (MGD) patients undergoing cataract surgery.This single-center pilot included 25 eyes 23 who had visually significant and concomitant MGD-associated dry eye at least 1 were willing undergo TPS wait for 6 weeks tear film stabilization prior surgery. Post-TPS keratometric readings used presurgical planning, actual postoperative residual refractive (RRA) was...
To compare the ocular surface tolerability of latanoprost 0.005% preserved with 0.02% benzalkonium chloride (BAK), bimatoprost 0.03% BAK, and travoprost 0.004% proprietary preservative system sofZia in patients previously treated latanoprost.This randomized, multicenter, investigator-masked, parallel-group study enrolled open-angle glaucoma or hypertension who had been on monotherapy for at least 4 weeks. At baseline, were randomized to receive once-daily (n=35), (n=38), (n=33) 3 months....
To evaluate the efficacy and safety of iTEAR, a novel, portable, sonic external neuromodulation device, for treatment dry eye disease (DED).This was multicenter, open-label, single-arm clinical trial that included adult patients with DED Schirmer score ≤10 mm in at least one eye. Enrolled subjects were instructed to apply study device twice per day 30 seconds bilaterally nasal nerve. After initial baseline visit, followed up days 3, 14, 30, 90, 180. The primary endpoint index (change from...
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Dry eye disease (DED) prevalence is estimated at 9.3% of the US adult population, although diagnosed rate much lower. This study examined real-world incidence rates (IR) and (PR) DED in adults using continuous positive airway pressure (CPAP) or nasal mask therapy (NMT) devices to treat sleep apnea.Using IBM MarketScan Commercial Medicare Supplemental claims databases, this identified with ≥1 claim CPAP other NMT device between January 1, 2014 June 30, 2018, diagnosis apnea during a 12-month...
To evaluate the efficacy of topical cyclosporine 0.1% in chondroitin sulfate emulsion for treatment dry eye.This retrospective multicenter study included 100 eyes 50 eye patients aged ≥18 years, with preoperative ocular surface disease index (OSDI) score >12 or corneal staining grade >1 (in either eye) who underwent (Klarity-C, ImprimisRx) 3 months. Postoperative evaluation comparison changes OSDI and after months from baseline.From baseline to months, a statistically significant improvement...
Dry eye disease (DED) is a disorder characterized by loss of tear film homeostasis that causes ocular surface inflammation and damage. The incidence DED increases with age. Cyclosporine ophthalmic solution 0.09% (CEQUA®; OTX-101), cyclosporine emulsion 0.05% (Restasis®; CsA), lifitegrast 5% (Xiidra®; LFT) are anti-inflammatory agents indicated for DED. This analysis compared treatment patterns in patients receiving OTX-101, CsA, or LFT.This real-world, retrospective, longitudinal cohort...
The purpose was to characterize the biomarkers associated with Sjögren's syndrome (SS) identified in serological samples of patients recalcitrant dry eye disease; additionally, modalities utilized treatment disease were evaluated for subsets and without SS.Data this retrospective, single-center, pilot study based on a chart review 48 sequential who SS via analysis. Data presented include presence autoantibodies through biomarker analysis identification concurrent modalities.Eleven out (23%)...
Patients implanted with a range-of-vision intraocular lens (IOL) (multifocal or extended depth of focus, EDOF) may be more susceptible to visual disturbances from poor tear film quality, and prophylactic treatment meibomian gland dysfunction (MGD) has been recommended. The purpose was evaluate whether vectored thermal pulsation (LipiFlow™) prior cataract surgery IOL safely improves postoperative outcomes. This is prospective, randomized, open-label, crossover, multicenter study patients...
Purpose: To assess the presence and severity of acquired blepharoptosis (ptosis) among patients visiting an eye care clinic receptivity eligible to pharmacologic treatment with oxymetazoline 0.1% ophthalmic solution.Patients Methods: Patients aged 50 years or older who had a scheduled appointment for any reason (eg, dry eye, cataract surgery consultation) were asked respond written questions about lid position select whether their upper most closely matched one 4 images shown them...
Purpose: To characterize intraocular pressure (IOP) response after treatment with dexamethasone suspension 9% vs placebo (vehicle) injection or topical prednisolone acetate 1% and to identify factors associated increased IOP cataract surgery. Setting: Data were pooled from two multicenter phase 3 clinical trials of patients undergoing routine Design: Randomized, double-blind study open-label study. Methods: Subjects randomized in the 1 2. who experienced 10 mm Hg greater, 15 20 greater...
To describe the early real-world experience of physicians with an intracanalicular dexamethasone insert (DEX) in patients undergoing cataract surgery and to capture clinical impact adopting this therapy.23 United States sites including Ambulatory Surgical Center Setting (ASC) Outpatient Clinical settings. Respondents were who had DEX patients. This was a Phase 4 experiential cross-sectional survey study comprised 3 sequential online physician surveys. Descriptive statistics summarized...
Purpose: To evaluate both the early experience of real-world patients treated with dexamethasone ophthalmic insert (0.4 mg; DEXTENZA ® ), hereafter referred to as DEX, after cataract surgery well staff/practice integration DEX relative eyedrops. Patients and Methods: This was a cross-sectional survey study 23 practices in United States. Respondents were practice staff who had following surgery. Both completed an online survey. Descriptive statistics summarized responses portray respondents....
Current trends and recent legislative changes have increased the pressure to control healthcare costs, especially those associated with running ophthalmic practices. These factors driven practice consolidation, reduced consultation times, use of electronic health record systems, encouraged more meaningful technology. At same time, patient expectations standards clinical care are both rising. This climate could discourage investment in new technology encourage intensity service, higher...