A5077369215- Oral and Maxillofacial Pathology
- Oral microbiology and periodontitis research
- Head and Neck Surgical Oncology
- Endodontics and Root Canal Treatments
- Dental Radiography and Imaging
- Cytomegalovirus and herpesvirus research
- Periodontal Regeneration and Treatments
- Herpesvirus Infections and Treatments
- dental development and anomalies
- Anesthesia and Pain Management
- Dental Anxiety and Anesthesia Techniques
- Dental Implant Techniques and Outcomes
- Bone Tumor Diagnosis and Treatments
- Hedgehog Signaling Pathway Studies
- Viral-associated cancers and disorders
- Inflammatory mediators and NSAID effects
- Plasma Applications and Diagnostics
- Bone Tissue Engineering Materials
- Regional Development and Management Studies
- Parvovirus B19 Infection Studies
- NF-κB Signaling Pathways
- Corneal Surgery and Treatments
- Osteomyelitis and Bone Disorders Research
- Electrospun Nanofibers in Biomedical Applications
- Tunneling and Rock Mechanics
University of Belgrade
2014-2023
Grade Medical (Czechia)
2013
This study aimed to compare the levels of tumour necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β) and interleukin-6 (IL-6) between apical periodontitis lesions with different clinical histological features. Based on data history disease, 100 human were categorised as either asymptomatic or symptomatic lesions. According examination, divided into periapical granulomas radicular cysts. Pulp tissues 25 impacted wisdom teeth used controls. Homogenised tissue samples centrifuged...
To investigate whether apical periodontitis lesions infected by Epstein-Barr virus (EBV) exhibit higher levels of oxidative stress biomarkers [8-hydroxydeoxyguanosine (8-OHdG) and oxidized glutathione (GSSG)] bone resorption regulators [receptor activator nuclear factor (NF-κB) ligand (RANKL) osteoprotegerin (OPG)] compared to EBV-negative periapical healthy pulp tissues.The experimental group consisted 30 EBV-positive collected in conjunction with apicoectomy. The tissues 20 impacted third...
Objectives This study aimed to analyse Epstein–Barr virus ( EBV ) and human cytomegalovirus HCMV viral loads in symptomatic asymptomatic apical periodontitis lesions, determine levels of TNF ‐α, IL ‐1β ‐6 these lesions investigate a possible correlation between herpesviral copy numbers proinflammatory cytokines. Materials Methods A total 100 samples were subjected analysis by nested polymerase chain reaction PCR TaqMan real‐time . The concentrations determined ELISA method. SPSS software was...
Introduction: Recent studies suggest that some viruses, including human cytomegalovirus (CMV), may be involved in the pathogenesis of periapical lesions. Since cysts (PCs) represent next stage evolution granuloma, it seemed reasonable to investigate presence CMV PCs and any possible relationship between its clinical features those cysts, as well compare results obtained with corresponding findings non‐inflammatory lesions, like odontogenic keratocysts (OKCs). Methods: Samples 33 10 OKCs, at...
ABSTRACT Objective: To analyze radiographic predictors for lower third molar eruption among subjects with different anteroposterior skeletal relations and of age groups. Materials Methods: In total, 300 molars were recorded on diagnostic digital orthopantomograms (DPTs) lateral cephalograms (LCs). The radiographs grouped according to sagittal intermaxillary angle (ANB), subject age, level eruption. DPT was used retromolar space, mesiodistal crown width, space/width ratio, second angulation...
To investigate the possible association between TNFα (-308 G/A) and IL-1β (-511 C/T) single nucleotide polymorphisms (SNPs) GSTT GSTM deletion risk of apical periodontitis (AP) development, determine different genotypes with presence herpesviral infection in AP.The study included 120 periapical lesions 200 control samples. Gene polymorphism analysis was performed using either polymerase chain reaction (PCR) or PCR/ restriction fragment length (RFLP). Relative gene expression TNF-α analysed...
The aim of this study was to investigate the expression survivin, an inhibitor apoptosis, in odontogenic keratocysts and compare it findings non-neoplastic jaw cysts - periapical cysts, as well establish a possible relationship between survivin human cytomegalovirus presence within these cysts.Samples 10 (five positive five negative for cytomegalovirus, determined by polymerase chain reaction) presence) were analysed. assessed immunohistochemical methods, using monoclonal antibody that...
Andric M, Nikolic N, Boskovic Milicic B, Skodric S, Basta Jovanovic G, Milasin J. Survivin gene promoter polymorphism ‐ 31G/C as a risk factor for keratocystic odontogenic tumor development. Eur J Oral Sci 2012; 120: 9–13. © 2012 Several single nucleotide polymorphisms in survivin promoters, notably ‐31G/C, have been shown to modulate the expression and activity of protein. Consequently, ‐31G/C has identified development several types tumors. The aim this study was investigate possible...
Background: Surgical removal of impacted lower third molars is a common oral surgical procedure, generally followed by moderate to severe postoperative pain.Transdermal drug delivery as concept offers interesting possibilities for pain control.The aim this study was evaluate the efficacy transdermal system with fentanyl in relieving following molar surgery.Material and Methods: Seventeen patients bilateral were included preliminary study.For control, randomly received patch plus placebo...
Objectives: This study aimed to investigate whether Epstein-Barr virus (EBV) positive periapical lesions exhibited higher mRNA levels of Notch signalling molecules (Notch2 and Jagged1), bone resorption regulators (receptor activator nuclear factor kappa-β ligand (RANKL) osteoprotegerin (OPG)), proinflammatory cytokines (tumour necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β) IL-6) compared EBV negative lesions. Additionally, the potential correlation between investigated in was...
Objectives: Bone vascularity is an important factor in process of osseointegration. The aim this study was to find whether or not blood perfusion the bone around prepared implant sites influences subsequent stability. Methods: Patients with bilaterally edentulous mandible were treated dental implants. previously noted using Laser Doppler Flowmetry (LDF). Implant stability quotient (ISQ) measured during follow-up period 26th week. Statistical distribution and correlation between LDF ISQ...