A5100402617- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiovascular Syncope and Autonomic Disorders
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Renin-Angiotensin System Studies
- Acute Ischemic Stroke Management
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Lipoproteins and Cardiovascular Health
- Cardiac Fibrosis and Remodeling
- Heart Failure Treatment and Management
- Atherosclerosis and Cardiovascular Diseases
- Vitamin C and Antioxidants Research
- Kruppel-like factors research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Platelet Disorders and Treatments
- Neurological Disease Mechanisms and Treatments
- Neurological Disorders and Treatments
- Cardiomyopathy and Myosin Studies
- Nuclear Receptors and Signaling
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Hormonal Regulation and Hypertension
Huashan Hospital
2010-2025
Fudan University
2010-2025
First Affiliated Hospital of Xinjiang Medical University
2025
Xinjiang Medical University
2025
Second Hospital of Shandong University
2024
Weifang Medical University
2023
First Hospital of China Medical University
2022
China Medical University
2022
Affiliated Hospital of Qingdao University
2022
Qingdao University
2022
The purpose of this study was to investigate the effects hyperglycemia on atrial interstitial fibrosis, ionic remodeling and vulnerability fibrillation (AF) in alloxan-induced diabetic rabbits.Sixty Japanese rabbits were randomly assigned group (n=30) control (n=30). Ten each respectively used electrophysiological histological study, patch-clamp Western blotting analysis. Langendorff perfusion record inter-atrial conduction time (IACT), effective refractory period (AERP) dispersion (AERPD)...
Abstract Background Sepsis-induced myocardial injury is a serious complication of sepsis. QT prolongation proarrhythmic state which reflects in group heterogeneous disorders. However, the study on clinical value sepsis limited. Methods We aimed to investigate characteristics and predictors new-onset its impact outcome multicenter retrospective cohort study. Electrocardiographic data were collected from patients with wards intensive care units four centers after exclusion QT-influencing...
Previous studies have mostly investigated the risk factors affecting occurrence of leukoaraiosis and severity in patients with ischemic stroke, but there are relatively few on clinical characteristics population most common type first-episode stroke caused by intracranial atherosclerotic stenosis China.
To investigate the effects of metoprolol succinate combined with Entresto (Sacubitril Valsartan Sodium Tablets) on cardiac function and coagulation in patients congestive heart failure (CHF).About 120 CHF treated from April 2018 to 2021 were enrolled our hospital. The arbitrarily assigned into control group study group. was cured sustained-release tablets, tablets Entresto. curative effect, function, vascular endothelial oxidative stress, compared.First all, we compared general data, there...
Abstract Background and Objectives A novel wide-band dielectric mapping system, named as KODEX-EPD (EPD Solutions, Philips, Best, the Netherlands), was effectively used in EA for atrial fibrillation (AF) ablation. To date, only a few studies have concentrated on application of system ablating supraventricular tachycardia or ventricular premature beats (VPBs) human models. This study aims to assess applicability efficiency three-dimensional electro-anatomic (EA) improve success rate Methods...
Objective: The objective of this article is to investigate the possible role atrial natriuretic peptide (ANP) in Angiotensin-(1–7) (Ang-(1–7)) signaling pathway on electrical and structural remodeling a chronic rapid pacing canine model. Methods: Twenty-four dogs were randomly assigned four groups: sham group, paced control + Ang-(1–7) group A-71915 group. Atrial (ARP) at 600 bpm was maintained for 14 days except animals from During pacing, (6 μg•kg-1•h-1) or (ANP receptor antagonist, 0.30...
Background: Vitamin K antagonists (VKAs) have been recommended as first-line anticoagulants for patients with left ventricular thrombosis (LVT). Direct oral (DOACs) are used an alternative to the standard of care in anticoagulation. The aim this meta-analysis was compare efficacy and safety VKAs DOACs treatment LVT. Materials Methods: Studies were identified by searching PubMed, Web Science, Embase. main outcomes included stroke or systemic embolism (SSE), thrombus resolution, bleeding...
Background/aim: This study aimed to evaluate pulmonary vein (PV) anatomy using 256-slice computed tomography (CT), which may be necessary for electrophysiologists know before radiofrequency catheter ablation (RFCA) therapy.Materials and methods: A total of 102 patients with paroxysmal persistent atrial fibrillation underwent cardiac CT angiography prior ablation. PV morphology, ostial diameter, orientation, distance from ostium first bifurcation were evaluated three-dimensional...
Abstract Background The relationship between HbA 1c , blood pressure, and carotid atherosclerosis in nondiabetic patients is not clear. Hypothesis pressure can affect carotid‐artery patients. Methods This retrospective cross‐sectional study included 216 without diabetes mellitus. A positive ultrasonographic result was defined as intima‐media thickness of the common artery ≥ 0.9 mm, or presence plaque. Results Compared with atherosclerosis, had significantly higher levels systolic (SBP)....
Objective This study aimed to evaluate the effects of moderate chronic kidney disease (CKD) and left atrial enlargement on risks thromboembolic events, all-cause cardiovascular mortalities in elderly patients with fibrillation (AF). Methods We retrospectively studied 751 (82.16% men, mean age: 79.0±9.1 years) AF who were followed up for an average 34.5 months at a single center. Adjusted hazard ratios (HRs) risk factors adverse clinical events calculated using Cox proportional hazards model....
Nonvalvular atrial fibrillation (NVAF) and intracranial atherosclerotic stenosis (ICAS) are major causes of ischemic stroke. Relatively few studies have focused on the risk factors clinical features stroke caused by NVAF combined with ICAS.We retrospectively evaluated and/or ICAS in patients acute admitted within 72 h after All underwent diffusion-weighted magnetic resonance imaging (DWI), angiography (MRA), computed tomography (CTA), digital subtraction (DSA). was detected routine...
Aberrant conduction during orthodromic reciprocating tachycardia (ORT) prolongs the ventriculoatrial time, which can be essential for maintenance of in specific cases. We searched ORT relying on aberrancy among 220 cases our center. Three patients showed phenomenon aberrancy-dependent ORT. All accessory pathways were located at lateral regions atrioventricular annulus. None them had a baseline bundle branch block (BBB). Creating functional BBB was necessary to induce tachycardias. In two...
Oral anticoagulation is efficient to prevent ischemic stroke in atrial fibrillation (AF), but very old patients, physicians always remain cautious use anticoagulants concerning the bleeding risk. This research aims investigate current situation of oral therapy (≥ 80 years) AF patients.We carried out a cross-sectional study an urban area China from 2014 2016. Characteristics patients (age ≥ and younger < were compared. Logistic analysis was used estimate association between CHA2DS2-VASc...