Saad H. Alotaibi

ORCID: 0000-0003-4212-2041
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About
Contact & Profiles
Research Areas
  • Synthesis and biological activity
  • Synthesis and Biological Evaluation
  • Click Chemistry and Applications
  • Congenital Diaphragmatic Hernia Studies
  • Adsorption and biosorption for pollutant removal
  • Advanced ceramic materials synthesis
  • Advanced materials and composites
  • Neonatal Respiratory Health Research
  • Antimicrobial Peptides and Activities
  • Intermetallics and Advanced Alloy Properties
  • Computational Drug Discovery Methods
  • Heavy Metals in Plants
  • Nanoparticles: synthesis and applications
  • Chemical Synthesis and Characterization
  • Essential Oils and Antimicrobial Activity
  • Biochemical and Structural Characterization
  • Photochromic and Fluorescence Chemistry
  • Coccidia and coccidiosis research
  • Synthesis and Reactivity of Heterocycles
  • Pomegranate: compositions and health benefits
  • Extraction and Separation Processes
  • Pharmacological Effects of Natural Compounds
  • Medical Imaging Techniques and Applications
  • Multicomponent Synthesis of Heterocycles
  • Respiratory Support and Mechanisms

Ministry Of Health
2025

Taif University
2016-2024

King Saud University
2024

King Fahad Specialist Hospital
2024

Hera General Hospital
2024

King Saud bin Abdulaziz University for Health Sciences
2024

Security Forces Hospital
2024

Arabian Gulf University
2023

Armed Forces Hospital
2023

Riyadh Armed Forces Hospital
2023

Nemours effective management tactics were used to reduce world crop losses caused by plant-parasitic nematodes. Nowadays the metallic nanoparticles are easily developed with desired size and shape. Nanoparticles (NPs) technology becomes a recognized need for researchers. Ecofriendly biosafe SiNPs from microorganisms. Recently, silicon (SiNPs) have gained novel pesticide properties against numerous agricultural pests. This study assessed biosynthesis of

10.1016/j.sjbs.2021.10.013 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2021-10-12

Soil potassium (K) supplement depends intensively on the application of chemical fertilizers, which have substantial harmful environmental effects. However, some bacteria can act as inoculants by converting unavailable and insoluble K forms into plant-accessible forms. Such are an eco-friendly approach for enhancing plant absorption consequently reducing utilization fertilization. Therefore, present research was undertaken to isolate, screen, characterize solubilizing (KSB) from rhizosphere...

10.3390/molecules26195758 article EN cc-by Molecules 2021-09-23

The intensive use of antimicrobial agents has led to the emergence multidrug resistance (MDR) among microbial pathogens. Such infections become more problematic in chronic diseases which efficacy chemotherapeutic is highly reduced. To combat problem drug resistance, inhibition bacterial quorum sensing (QS) and biofilms are considered as promising strategies development anti-infective agents. In this study, gold nanoparticles (AuNPs-CA) were biofabricated using Capsicum annuum aqueous extract...

10.1021/acsomega.1c02297 article EN cc-by-nc-nd ACS Omega 2021-06-16

Chemical insecticides have many harmful effects, including as foodborne residues and environmental contaminants, well side effects on natural enemies serious risks for human health. The use of plant-derived essential oils (EOs) effective bio-agents has become an component integrated pest management. In this study, the contact toxicity, deterrent, repellent activities were evaluated obtained from Mentha piperita, longifolia, Salvia officinalis, rosmarinus, grown at high altitudes in Taif...

10.3390/plants11030463 article EN cc-by Plants 2022-02-08

Abstract A new series of nucleosides, moieties, and Schiff bases were synthesized from sulfadimidine. Infrared (IR), 1 HNMR, 13 C NMR, mass spectrometry techniques elemental analysis employed to elucidate the compounds. The prepared analogues purified by different chromatographic (preparative TLC column chromatography). Molecular docking studies compounds 3a, 4b, 6a, 6e demonstrated binding mode involved in active site DNA gyrase. Finally, all tested against selected bacterial strains. most...

10.1038/s41598-021-97297-1 article EN cc-by Scientific Reports 2021-09-09

This study aims to evaluate the functionalization of chitosan biopolymer with heterocyclic moieties 2-thioxodihydropyrimidine-4,6(1H,5H)-dione used for enhancing sorption Cr ions from aqueous solution. A synthesized sorbent is a nanoscale particle (around 5–7 nm), which explains fast kinetics sorption. The specified using elemental analysis (EA), FTIR, BET (nitrogen desorption isotherms), TGA, and SEM-EDX analyses. Sorption properties are investigated ultraviolet emission (UV) but also...

10.3390/catal12070678 article EN Catalysts 2022-06-21

The synthesis and developments of magnetic chitosan nanoparticles for high efficiency removal the cadmium ions from aquatic medium are one most challenging techniques. Highly adsorptive composite (MCH-ATA) was produced by reaction with formaldehyde amino thiazole derivative. sorbent characterized FTIR, elemental analyses (EA), SEM-EDX, TEM analysis, TGA titration (volumetric). modified material includes nitrogen sulfur contents (i.e., 4.64 1.35 mmol g−1, respectively), compared to pristine...

10.3390/polym14061240 article EN Polymers 2022-03-18

This study aims to assess the deterioration aspects of a historical manuscript dating back 14th century that was deposited in Library Arabic Language Academy, Cairo, Egypt. The at exploration role various fungal strains had colonized this deteriorated its biodeterioration through their efficacy secretion hydrolytic enzymes. To evaluate deterioration, techniques, including visual inspection, attenuated total reflectance Fourier transform infrared (ATR-FTIR), scanning electron microscopy...

10.3390/life12111821 article EN cc-by Life 2022-11-08

Background: Chronic or complex wounds present a significant healthcare challenge due to their multifactorial etiology and the nature of healing process. These often fail heal with standard treatments, causing prolonged suffering for patients considerable costs. This review discusses nursing intervention protocols management wounds, emphasizing both local systemic factors that influence wound healing. The need multidisciplinary approach is evident in improving outcomes wounds. Aim: aim this...

10.62754/joe.v3i8.5788 article EN cc-by-nc-nd Journal of Ecohumanism 2025-01-11

An experiment was carried out to investigate the effects of different mineral fertilizers on contents in turmeric rhizomes and soil enzyme activities properties under field conditions Uzbekistan. The present study is first report impact enzymes with four treatments: T1—Control, T2—N75P50K50 kg/ha, T3—N125P100K100 T4—N100P75K75 + B3Zn6Fe6 kg/ha. Turmeric samples were collected from experiments at Surkhandarya scientific experimental station vegetable, melon crops potato research institute,...

10.3390/su13169437 article EN Sustainability 2021-08-23

In this work, we design and then synthesis of new derivatives nucleosides, oxadiazoline containing acetylated sugars α-aminophosphonate derivatives. The synthesized compounds have been elucidated by different spectroscopic analysis, such as, elemental 13C NMR, infrared (IR) 1H NMR. previously were purified tested against breast cancer cells (MCF-7). results showed that the 5d, 6b, 7a 9h moderate to very high activity cancer, with incidence rates 78.45%, 84.60%, 93.45% 95.78%, respectively....

10.1016/j.arabjc.2021.103348 article EN cc-by Arabian Journal of Chemistry 2021-07-29

The aim of this study was to examine the effect some natural compounds against multidrug-resistant bacteria.Forty-three bacterial strains were collected. Disc diffusion and minimum inhibitory concentration (MIC) tests carried out for including quercetin, Acacia nilotica, Syzygium aromaticum, Holothuria atra. Scanning electron microscope analysis DNA apoptosis assays performed.Staphylococcus aureus resistant imipenim, ampicillin, penicillin. Most Escherichia coli amoxicillin, clavulanat,...

10.1177/1559325820936189 article EN cc-by-nc Dose-Response 2020-07-01

This study aimed to investigate the prevalence and intensity of external parasites in domestic pigeons Giza, Egypt, from January 2020 December 2020. A total 300 (25 per month) were examined. The birds divided into groups based on their age. oxidative stress parameters; serum zinc concentration, malondialdehyde (MDA), Nitric oxide evaluated single mixed parasitic infestations. examined was 80.3%. detected Pseudolynchia canariensis (P. canariensis), Hippobosca equina (H. equina), Columbicola...

10.1016/j.sjbs.2021.10.042 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2021-10-22

Globally, there is a rising demand for water purification. This driven by numerous factors, including economic growth, increasing population, shortage, and deterioration of quality. The current work highlights the manufacturing environmentally friendly highly efficient sorbent based on chitosan nanoparticles after successive crosslinking (using glutaraldehyde) modification through grafting 4-aminoazobenzene-3,4′-disulfonic acid (AZDS) as source sulfonic groups. First, produced was thoroughly...

10.3390/catal12070721 article EN Catalysts 2022-06-30

Women's health is affected by breast cancer worldwide and Saudi Arabia (SA) no exception. Malignancy has enormous consequences for social, psychological public health. The aim of this study was to examine the risk factors women from using logistic regression models. In 135 patient cases different stages used case management, 270 healthy King Abd Alla Medical City, Mecca, SA were taken predict probability developing cancer, analyzed taking such as age, marital status, family history, parity,...

10.1016/j.sjbs.2020.02.012 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2020-03-02

Amorphous solid dispersion (ASD) has emerged to be an outstanding strategy among multiple options available for improving solubility and consequently biological activity. Interestingly several binary SD systems continue exhibit insufficient over time. Therefore, the goal of current research was design ternary amorphous dispersions (ASDs) hydrophobic model drug curcumin (CUR) enhance dissolution rate in turn, presenting enhanced anti-bacterial, antioxidant anti-inflammatory For this purpose...

10.1016/j.heliyon.2024.e34636 article EN cc-by-nc Heliyon 2024-07-01
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