A5047894464- Influenza Virus Research Studies
- Animal Virus Infections Studies
- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Virology and Viral Diseases
- Viral Infections and Vectors
- Coccidia and coccidiosis research
- Herpesvirus Infections and Treatments
- Bird parasitology and diseases
- Respiratory viral infections research
- Viral Infections and Immunology Research
- Animal Nutrition and Physiology
- Vector-Borne Animal Diseases
- Helminth infection and control
- interferon and immune responses
- Poxvirus research and outbreaks
- Selenium in Biological Systems
- Autism Spectrum Disorder Research
- Microbial infections and disease research
- Biosensors and Analytical Detection
- Rabbits: Nutrition, Reproduction, Health
- Peroxisome Proliferator-Activated Receptors
- vaccines and immunoinformatics approaches
- Bacteriophages and microbial interactions
- Essential Oils and Antimicrobial Activity
Agricultural Research Center
2020-2025
Ministry of Agriculture and Land Reclamation
2022
Animal Health Research Institute
2021
Cairo University
2021
ORCID
2020
The evolution and adaptation of highly pathogenic avian influenza (HPAI) viruses pose ongoing challenges for animal public health. We investigated the characteristics newly emerged H5N1/2022 H5N8/2022 clade 2.3.4.4b compared to previously circulating H5N1/2016 2.2.1.2 in Egypt using both murine models. All strains demonstrated a 100% mortality chickens after intranasal inoculation (106 EID50), while strain showing significantly higher viral shedding (8.34 ± 0.55 log10 EID50). Contact...
Widespread prevalence of avian influenza H9N2 subtype in the Middle East region and its detection Egypt quail early summer 2011 added another risk factor to Egyptian poultry industry addition highly pathogenic H5N1 subtype. This situation increases need for further surveillance investigation viruses commercial household chickens. work describes genetic characterization recently isolated from chicken flocks. Parallel infections has also been done compare two subtypes close geographic...
This study aimed to evaluate the efficacy of chitosan-silver nanocomposites in treatment experimentally infested pigeons with Pseudolynchia canariensis (P. canariensis) evaluation different immunological parameters before and after treatment. Therefore, fourteen birds were divided into 2 groups; group1(infested group including 12 birds) which subdivided 6 sub-groups each, five them treated sub-group number was deltamethrin while, two kept as control negative ones. P. flies distributed under...
Parasitism is a divesting problem that frequently overlooked and may result in severe prominent clinical manifestation. This study aimed to investigate the seasonal sexual prevalence of gastrointestinal nematode Ascaridia columbae (A. columbae) infection among domestic pigeons Giza governorate, Egypt, during period from 2020 2021. One hundred sixty suspected were clinically investigated. Blood & tissue samples collected infected birds estimate serum zinc concentration, malondialdehyde (MDA),...
This study aimed to investigate the prevalence and intensity of external parasites in domestic pigeons Giza, Egypt, from January 2020 December 2020. A total 300 (25 per month) were examined. The birds divided into groups based on their age. oxidative stress parameters; serum zinc concentration, malondialdehyde (MDA), Nitric oxide evaluated single mixed parasitic infestations. examined was 80.3%. detected Pseudolynchia canariensis (P. canariensis), Hippobosca equina (H. equina), Columbicola...
Highly pathogenic avian influenza (HPAI) is a serious viral infection that causes massive economic losses in poultry. The current study investigated the HPAI virus prevalence commercial broiler chicken flocks from 2019 to 2022. Organ samples, including trachea, cecal tonsils, spleen, brain, as well tracheal and cloacal swabs, were harvested 111 problematic suffered variable mortalities accompanied with respiratory signs (103 H5-vaccinated 8 nonvaccinated flocks) Egypt during observation...
Controlling avian influenza viruses (AIVs) is mainly based on culling of the infected bird flocks or via implementation inactivated vaccines in countries where AIVs are considered to be endemic. Over last decade, several virus subtypes, including highly pathogenic (HPAI) H5N1 clade 2.2.1.2, H5N8 2.3.4.4b and recent 2.3.4.4b, have been reported among poultry populations Egypt. This demanded utilization a nationwide routine vaccination program sector. Antigenic differences between available...
The highly pathogenic avian influenza (HPAI) H5N8 virus was first detected in Egypt late 2016. Since then, the has spread rapidly among different poultry sectors, becoming dominant HPAI H5 subtype reported Egypt. Different genotypes of were Egypt; however, geographic patterns and molecular evolution Egyptian viruses are still unclear. Here, extensive epidemiological surveillance conducted, including more than half a million samples collected from sectors (farms/backyards/live bird markets)...
A proper vaccination against avian influenza viruses in chicken can significantly reduce the risk of human infection. Egypt has highest number recorded humans highly pathogenic (HPAI)-H5N1 infections worldwide despite widespread use homologous vaccines poultry. Enhancing H5N1 vaccine efficacy is ultimately required to better control HPAI-H5N1. The aim this study boost immunity by combined with inactivated HPAI-H5N1 selenium nanoparticles (SeNPs). chickens groups 1-3 were fed diets...
Duck hepatitis A virus (DHAV) causes acute and mortality, resulting in high economic losses the duck farm industry. The current study describes outbreak of DHAV vaccinated farms North Egypt during 2019 molecular characterization 3′ untranslated region (UTR) viral protein VP1 genes. 30 samples were collected from 7- to 28-day-old commercial Pekin ducks that showed a history nervous signs sudden deaths on 6 governorates. was typed by reverse transcription–polymerase chain reaction (RT-PCR) for...
Gumboro virus is one of the most dangerous immunosuppressant viruses that infect chickens and causes massive financial losses worldwide. The current study aims to conduct a molecular characterization chicken farms for infectious bursal disease (IBDV). Based on postmortem (PM) lesions, 125 samples from 25 were collected clinically diseased commercial with increased mortality suspected infection. Pooled IBD-vaccinated flocks tested IBDV by reverse transcriptase polymerase chain reaction...
Highly pathogenic avian influenza (HPAI) viruses continue to circulate worldwide, causing numerous outbreaks among bird species and severe public health concerns. H5N1 H5N8 are the two most fundamental HPAI subtypes detected in birds last decades. The may compete with each other while sharing same host population and, thus, suppress spread of one viruses. In this study, we performed a statistical analysis investigate temporal correlation using globally reported data 2015–2020. This was...
Avian influenza (AI) viruses pose a risk to the worldwide poultry industry. Ultimately, improving efficiency of H9N2 vaccine is necessary better control low-pathogenic avian influenza-H9N2 by using natural immunostimulant. Therefore, goal present study was examine varying doses cyanobacterium Spirulina extract on effectiveness vaccine. Thus, total 150 specific pathogen-free (SPF) chickens were allocated into 6 groups, 25 birds each, as follow: G1, G2, and G6 supplemented with 200, 400, 400...
Fifty broiler chicks were divided into five groups to study the antiviral and immune-stimulant effect of Allium cepa essential oils (ACEO). The administration single or combined with NVD vaccine in broilers, more than one parameter was studied this i.e., clinical symptoms that appeared on after experimental infection velogenic Newcastle disease virus, postmortem lesions, pathological lesions scoring, mortality rate (MR), viral shedding, birds immunity assessed by HI test protection percent...
The H9N2 subtype of avian influenza A virus (aIAV) is circulating among birds worldwide, leading to severe economic losses. cocirculation with other highly pathogenic aIAVs has the potential contribute rise new strains pandemic potential. Therefore, rapid detection H9 infection crucial control spread. qualitative reverse transcription recombinase polymerase amplification (RT-RPA) assay for aIAV was developed. All results were compared gold standard (real-time chain reaction (RT-PCR)). RT-RPA...
In late 2016, Egypt encountered multiple cases of the highly pathogenic avian influenza (HPAI) virus H5N8 subtype. a previous study, three distinct genotypes, including A/common-coot/Egypt/CA285/2016 (H5N8) (CA285), A/duck/Egypt/SS19/2017 (SS19), and A/duck/Egypt/F446/2017 (F446), were isolated from wild birds, backyard, commercial farm, respectively, during first wave infection. this current we investigated differences in pathogenicity, replication transmissibility genotypes...
Avian influenza (AI) is a respiratory disease complex syndrome recently recorded in vaccinated flocks causing high economic losses. This study aimed to prepare inactivated vaccine from isolated field strains [highly pathogenic avian (HPAI) (H5N8) and low (LPAI) (H9N2)] compare the efficiency of two experimental vaccines some commercial H5 H9N2 laying hens. The obtained results indicated that identified (H5N8 H9N2) were protected AI as compared H5N1, H5N3, vaccines, which showed protection...