A5000004356- Animal Disease Management and Epidemiology
- Influenza Virus Research Studies
- Virology and Viral Diseases
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Mosquito-borne diseases and control
- Virus-based gene therapy research
- vaccines and immunoinformatics approaches
- Vector-Borne Animal Diseases
- Animal Virus Infections Studies
- Herpesvirus Infections and Treatments
- RNA and protein synthesis mechanisms
- Viral Infections and Vectors
- Syphilis Diagnosis and Treatment
Animal Health Research Institute
2023
Agricultural Research Center
2022-2023
Wild migratory birds have the capability to spread avian influenza virus (AIV) over long distances as well transmit domestic birds. In this study, swab and tissue samples were obtained from 190 during close surveillance in Egypt response recent outbreaks of highly pathogenic (HPAI) H5N1 virus. The collected tested for a variety AIV subtypes (H5N1, H9N2, H5N8, H6N2) other pathogens such NDV, IBV, ILT, IBDV, WNV. Among all samples, HPAI was found six samples; be negative pathogens. Egyptian...
Avian reovirus (ARV) strains cause a variety of symptoms in chickens, including viral arthritis/tenosynovitis, disease that has emerged as significant economic losses commercial chicken flocks recent years various countries, Egypt. Furthermore, ARV are frequently isolated from birds suffering malabsorption. In the actual study, seventy-five samples were collected 2021 and 2022 broiler vaccinated breeder at different farms Giza Province, Egypt, with reovirus-like such weight fluctuation...
Since the detection of antigenically atypical very virulent Infectious bursal disease viruses (vvIBDV) in Egypt 1999, country has been experiencing recurrent outbreaks with high mortality rates and typical gross lesions associated vvIBDV. However, a significant change occurred 2023, marked by notable increase reported subclinical IBDV cases. To evaluate field situation, samples from 21 farms 2023 18 2021 2022, all which had experienced IBD based on clinical diagnosis, were collected,...
The very virulent infectious bursal disease virus (vvIBDV) induces an acute, highly contagious and immunosuppressive in younger chicken causing massive economic losses globally. A major challenge the field’s clinical diagnosis is distinguishing gross lesions caused by vvIBDV from those induced classic IBDV (cIBDV), commonly used as live attenuated vaccines. This study introduces a one-step multiplex real-time PCR assay designed to distinguish between non-vvIBDV viruses. Via simultaneously...
The polymerase complex proteins (PB2, PB1, and PA) are responsible primarily for the replication of avian influenza virus play an important role in virulence, mammalian adaptation, interspecies transmission. In this study; eight Egyptian LPAI-H9N2 viruses isolated from apparent healthy chickens quails 2014 to 2016. Characterization complete nucleotide sequences, phylogenetic mutation analysis were carried out. measurement thermodynamic stability H9N2 protein comparison human H3N2 H1N1 was...
Since it was first discovered, the low pathogenic avian influenza (LPAI) H9N2 subtype has established linages infecting poultry population globally and become one of most prevalent subtypes in domestic poultry. Several different variants genotypes LPAI viruses have been reported Egypt, but little is known about their pathogenicity how they evolved. In this study, four Egyptian were genetically antigenically characterized compared to representative from G1 lineage. Furthermore, three distinct...
Abstract Infectious bursal disease viruses (IBDVs) have a profound impact on poultry production worldwide, directly causing mortality rates of up to 100%, and indirectly through their immunosuppressive effects. Since the emergence antigenically modified very virulent IBDV (vvIBDV) in Egypt late 1999, country has experienced recurrent outbreaks with high typical vvIBDV gross lesions. However, notable shift occurred 2023, characterized by substantial increase reported subclinical cases...
I nfectious bursal disease (IBD) viruses continue to cause considerable eco- nomic losses in the Egyptian poultry industry.The purpose of this study was investigate molecular features IBDV isolated Egypt from 2021 march 2022, and assess pathogenicity, immunogenicity, protection IBD immune-complex vaccinations (Transmune®-CEVA vaccine).Twenty-three field samples (bursa Fabricius) were collected broiler farms a highly variable region encompassing VP2 gene targeted for screening utilizing...